Zobrazeno 1 - 10
of 27
pro vyhledávání: '"William B. Wead"'
Autor:
Kevin G. Soucy, Guruprasad A. Giridharan, Carlo R. Bartoli, Dustin Phillips, Michael A. Sobieski, Robert D. Dowling, Zhongjun J. Wu, William B. Wead, Steven C. Koenig, Mark S. Slaughter, Sumanth D. Prabhu
Publikováno v:
Annals of Biomedical Engineering. 45:1475-1486
Continuous-flow left ventricular assist devices (CF LVADs) are rotary blood pumps that improve mean blood flow, but with potential limitations of non-physiological ventricular volume unloading and diminished vascular pulsatility. In this study, we te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec909404320a9eb0f808b5464eb1f80e
https://doi.org/10.1007/s10439-017-1804-x
https://doi.org/10.1007/s10439-017-1804-x
Bovine Model of Chronic Ischemic Cardiomyopathy: Implications for Ventricular Assist Device Research
Autor:
Steven C. Koenig, Leslie C. Sherwood, Carlo R. Bartoli, William B. Wead, Guruprasad A. Giridharan, Mark S. Slaughter, Sumanth D. Prabhu
Publikováno v:
Artificial Organs. 37:E202-E214
Ventricular assist devices (VADs) have emerged as a successful treatment option for advanced heart failure. The objective of this study was to develop a clinically relevant model of chronic ischemic cardiomyopathy to investigate functional, histologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c2c358a3379d8017b747086b73f5ca1
https://doi.org/10.1111/aor.12129
https://doi.org/10.1111/aor.12129
Autor:
Robert D. Dowling, Carlo R. Bartoli, Sumanth D. Prabhu, Steven C. Koenig, Guruprasad A. Giridharan, William B. Wead
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 144:402-408
Objective An ectopic coronary artery that courses between the aortic root and the pulmonary trunk may lead to sudden cardiac death, especially in athletes. It has been speculated that during exercise, compression of the coronary artery between the gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c23a5f774d171de9d7a5e9d86bde53f
https://doi.org/10.1016/j.jtcvs.2011.08.056
https://doi.org/10.1016/j.jtcvs.2011.08.056
Autor:
Jeff C. Falcone, Gary L. Anderson, Richard W. Stremel, Dale A. Schuschke, John C. Passmore, William B. Wead
Publikováno v:
Medical Science Educator. 21:8-20
The teaching faculty of the Department of Physiology and Biophysics at the University of Louisville School of Medicine have designed and implemented various “active learning” approaches within three different courses that teach physiology to medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bcf64bb4e28bb1eefafc4f1ef58bc89
https://doi.org/10.1007/bf03341589
https://doi.org/10.1007/bf03341589
Autor:
Galia K. Soukhova-O'Hare, David Gozal, William B. Wead, Lihua Li, Zixi Jack Cheng, Robert D. Wurster, Y. Lin, Binbin Yan
Publikováno v:
Neuroscience. 153:709-720
Chronic intermittent hypoxia (CIH) attenuates baroreflex control of heart rate (HR). In this study, we assessed whether CIH exposure reduced nucleus ambiguus (NA) control of HR and induced neural degeneration in the NA. Fischer 344 (age: 3-4 months)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27371245a0f66bebd2675d5d83d642ea
https://doi.org/10.1016/j.neuroscience.2008.01.066
https://doi.org/10.1016/j.neuroscience.2008.01.066
Autor:
Zixi Jack Cheng, David Gozal, Chenghui Huang, William B. Wead, Mark W. Chapleau, Lihua Li, Min Lin, Jing Ai, Rugao Liu, Robert D. Wurster
Publikováno v:
The Journal of Comparative Neurology. 509:103-117
The baroreflex control of heart rate (HR) is reduced following chronic intermittent hypoxia (CIH). Since the nucleus ambiguus (NA) plays a key role in baroreflex control of HR, we examined whether CIH remodels vagal efferent projections to cardiac ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9e37426bb11789e9f1d778ec13c61a
https://doi.org/10.1002/cne.21732
https://doi.org/10.1002/cne.21732
Autor:
Mark W. Chapleau, David Gozal, William B. Wead, Rugao Liu, Robert D. Wurster, Min Lin, Zixi Jack Cheng
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H997-H1006
Chronic intermittent hypoxia (CIH) leads to increased sympathetic nerve activity and arterial hypertension. In this study, we tested the hypothesis that CIH impairs baroreflex (BR) control of heart rate (HR) in mice, and that decreased cardiac chrono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea715a7b05bf64645effe477eeeb759
https://doi.org/10.1152/ajpheart.01124.2006
https://doi.org/10.1152/ajpheart.01124.2006
Autor:
Carlo R. Bartoli, William B. Wead, Guruprasad A. Giridharan, Sumanth D. Prabhu, Steven C. Koenig
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 144(6):1531-1533
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7268eb54449b14706aae23076c40702
Autor:
Roberto Bolli, Irving G. Joshua, Jason M. Pass, Jun Zhang, Yuting Zheng, Jiuming Gao, Peipei Ping, W. Keith Jones, William B. Wead, Christopher P. Baines, Xin Wu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 281:H2500-H2510
Recent investigations have established a role for the βII-isoform of protein kinase C (PKCβII) in the induction of cardiac hypertrophy and failure. Although receptors for activated C kinase (RACKs) have been shown to direct PKC signal transduction,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7852a774519973a6c7aa7353a83c7677
https://doi.org/10.1152/ajpheart.2001.281.6.h2500
https://doi.org/10.1152/ajpheart.2001.281.6.h2500
Autor:
William B. Wead, Shuang Huang, Peipei Ping, Yuting Zheng, Jiahuai Han, Roberto Bolli, Jun Zhang, Jiuming Gao, Xinan Cao, Richard C. Li
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 279:H1679-H1689
We have previously shown that protein kinase C (PKC)-epsilon, nuclear factor (NF)-kappaB, and mitogen-activated protein kinases (MAPKs) are essential signaling elements in ischemic preconditioning. In the present study, we examined whether activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c318469b592523f551b1718f28e816d
https://doi.org/10.1152/ajpheart.2000.279.4.h1679
https://doi.org/10.1152/ajpheart.2000.279.4.h1679