Zobrazeno 1 - 10
of 68
pro vyhledávání: '"William B. Upholt"'
Autor:
Stephen E. Harris, Mina Mina, Inga Marijanović, Haitao Li, William B. Upholt, Mary Louise Stover, Ivo Kalajzic, Jelica Gluhak Heinrich, Ivana Erceg, Alexander C. Lichtler, Mark S. Kronenberg, Dimitrios Velonis
Publikováno v:
Developmental Biology. 316:458-470
Our laboratory and others have shown that overexpression of Dlx5 stimulates osteoblast differentiation. Dlx5−/−/Dlx6−/− mice have more severe craniofacial and limb defects than Dlx5−/−, some of which are potentially due to defects in oste
Autor:
Minoru Omi, Robert A. Kosher, Gail Lizarraga, Chi-Kuang Leo Wang, Deborah Ferrari, William B. Upholt, Hsu-Chen Cheng, Caroline N. Dealy, Hsian-Jean Chin
Publikováno v:
Developmental Biology. 269:109-122
Several bone morphogenetic proteins (BMPs) are expressed in the apical ectodermal ridge (AER), a critical signaling center that directs the outgrowth and patterning of limb mesoderm, but little is known about their function. To study the functions of
Publikováno v:
Developmental Dynamics. 223:333-352
The mandibular processes are specified as at least two independent functional regions: two large lateral regions where morphogenesis is dependent on fibroblast growth factor (FGF)-8 signaling, and a small medial region where morphogenesis is independ
Autor:
Lauro Sumoy, Mark S. Kronenberg, Alexander C. Lichtler, Blanka Rogina, William B. Upholt, ZhongZong Pan, Dah-Yeou Huang
Publikováno v:
Biochemical and Biophysical Research Communications. 290:955-961
The apical ectodermal ridge (AER) is a specialized ectodermal region essential for limb outgrowth. Msx2 expression patterns in limb development strongly suggest an important role for Msx2 in the AER. Our previous studies identified a 348-bp fragment
Publikováno v:
Developmental Dynamics. 216:320-335
BMP-7 is a member of the BMP family of signaling molecules that are thought to play key roles in mediating inductive events during embryogenesis. In the present study the possible roles of BMP-7 in mediating inductive events during the initiation pha
Autor:
Thomas F. Linsenmayer, Eileen Gibney, David E. Birk, Nah, Bernard Dublet, William B. Upholt, Francis Igoe, Hyun-Duck, Jeffrey K. Marchant, Marion K. Gordon, Joseph W Foley, Michel van der Rest, Meyer Barembaum, Elida Rodriguez, Jeanne C. Myers
Publikováno v:
Matrix Biology. 18:481-486
Chicken alpha1(V) collagen cDNAs have been cloned by a variety of methods and positively identified. We present here the entire translated sequence of the chick polypeptide and compare selected regions to other collagen chains in the type V/XI family
Publikováno v:
Developmental Dynamics. 213:386-397
Previous observations have shown that, during the initiation phase of odontogenesis, signals from mouse odontogenic epithelium can elicit teeth in non-odontogenic but neural crest-derived mesenchyme isolated from ectopic sites including chick mandibu
Autor:
Deborah Ferrari, Alexander C. Lichtler, Caroline N. Dealy, William B. Upholt, Robert A. Kosher, ZhongZong Pan
Publikováno v:
Developmental Biology. 197(1):12-24
During early stages of chick limb development, the homeobox-containing gene Msx-2 is expressed in the mesoderm at the anterior margin of the limb bud and in a discrete group of mesodermal cells at the midproximal posterior margin. These domains of Ms
Autor:
Yi-Hsin Liu, Zhong Zong Pan, Rob Maxon, K. Mack, Alexander C. Lichtler, Stephen H. Clark, William B. Upholt, Mark S. Kronenberg, David W. Rowe, Antonio Bedalov, Gloria Gronowicz, Barbara E. Kream, Milan Dodig
Publikováno v:
Journal of Biological Chemistry. 271:16422-16429
Our previous studies have shown that the 49-base pair region of promoter DNA between -1719 and -1670 base pairs is necessary for transcription of the rat COL1A1 gene in transgenic mouse calvariae. In this study, we further define this element to the
Autor:
Robert A. Kosher, David W. Rowe, Alexander C. Lichtler, Stephen H. Clark, K. Mack, William B. Upholt, M. Reza Seghatoleslami
Publikováno v:
Matrix Biology. 14:753-764
To investigate the regulation of type II collagen gene expression in cells undergoing chondrogenic differentiation, we have employed a 5-kbp genomic fragment of the human type II collagen gene which contains 1.8 kbp of upstream sequences, the transcr