Zobrazeno 1 - 10
of 60
pro vyhledávání: '"William B. Lott"'
Autor:
Melissa E. Monterosso, Kathryn Futrega, William B. Lott, Ian Vela, Elizabeth D. Williams, Michael R. Doran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platfor
Externí odkaz:
https://doaj.org/article/2f5eb33aec0547329c75ee64f3601dbc
Autor:
Darren Leahy, Cameron Grant, Alex Jackson, Alex Duff, Nicholas Tardiota, Jessica Van Haeften, Xingchen Chen, Jonathan M. Peake, Michael D. Kruppa, Eliot T. Smith, David A. Johnson, William B. Lott, Jonathan M. Harris
Publikováno v:
Molecules, Vol 26, Iss 17, p 5344 (2021)
Human neutrophil elastase (HNE) is a uniquely destructive serine protease with the ability to unleash a wave of proteolytic activity by destroying the inhibitors of other proteases. Although this phenomenon forms an important part of the innate immun
Externí odkaz:
https://doaj.org/article/06c08418647744e288d41d3b67a423b3
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202079 (2018)
A mathematical model was developed for mesenchymal stromal cell (MSC) growth in a packed bed bioreactor that improves oxygen availability by allowing oxygen diffusion through a gas-permeable wall. The governing equations for oxygen, glucose and lacta
Externí odkaz:
https://doaj.org/article/78537c0c3afd4673a095740902b93739
Autor:
David A. Johnson, Cameron Grant, Xingchen Chen, Alex Jackson, Eliot T Smith, William B. Lott, Jonathan M. Peake, Alex Duff, Michael D. Kruppa, Darren Leahy, Jonathan M. Harris, Jessica Van Haeften, Nicholas Tardiota
Publikováno v:
Molecules
Volume 26
Issue 17
Molecules, Vol 26, Iss 5344, p 5344 (2021)
Volume 26
Issue 17
Molecules, Vol 26, Iss 5344, p 5344 (2021)
Human neutrophil elastase (HNE) is a uniquely destructive serine protease with the ability to unleash a wave of proteolytic activity by destroying the inhibitors of other proteases. Although this phenomenon forms an important part of the innate immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9168b5096ff4616f8c7247707edcaca
Autor:
William B. Lott, Kathryn Futrega, Michael R. Doran, Ian Vela, Melissa E. Monterosso, Elizabeth D. Williams
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platform, the Mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53e6943fc0caf892acf9d0c213ab7d3
https://doi.org/10.1038/s41598-021-84154-4
https://doi.org/10.1038/s41598-021-84154-4
Publikováno v:
Nature.
Written grant proposals are inefficient to prepare and review, and scoring is notoriously unreliable. It’s time to consider audio-visual alternatives. Written grant proposals are inefficient to prepare and review, and scoring is notoriously unrelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d33fb917d829868b1d57553327423df2
https://doi.org/10.1038/d41586-021-00341-3
https://doi.org/10.1038/d41586-021-00341-3
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
A previous study identified kartogenin (KGN) as a potent modulator of bone marrow mesenchymal stem/stromal cell (BMSC) chondrogenesis. This initial report did not contrast KGN directly against transforming growth factor-beta 1 (TGF-β1), the most com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5175607e12840fbc53afaa79e19ee8f3
https://doi.org/10.1038/s41598-020-65283-8
https://doi.org/10.1038/s41598-020-65283-8
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18197 (2011)
Infectious cDNA clones of RNA viruses are important research tools, but flavivirus cDNA clones have proven difficult to assemble and propagate in bacteria. This has been attributed to genetic instability and/or host cell toxicity, however the mechani
Externí odkaz:
https://doaj.org/article/d848f82ff91a4397905674aa9467ee9a
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19447 (2011)
While much of the genetic variation in RNA viruses arises because of the error-prone nature of their RNA-dependent RNA polymerases, much larger changes may occur as a result of recombination. An extreme example of genetic change is found in defective
Externí odkaz:
https://doaj.org/article/21b9da125dfb4ca6b410e6bdddbb9f32
Autor:
James W. Marsh, Peter Timms, Wilhelmina M. Huston, Vanissa A. Ong, William B. Lott, Joel D. A. Tyndall
Publikováno v:
Future Microbiology
© 2017 Future Medicine Ltd. Chlamydia trachomatis is the most prevalent sexually transmitted bacterial infection worldwide and the leading cause of preventable blindness. Reports have emerged of treatment failure, suggesting a need to develop new an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5cc83c3c5aad491e2c4351e45afef0
https://doi.org/10.2217/fmb-2017-0017
https://doi.org/10.2217/fmb-2017-0017