Zobrazeno 1 - 10
of 103
pro vyhledávání: '"William B Lott"'
Autor:
Melissa E. Monterosso, Kathryn Futrega, William B. Lott, Ian Vela, Elizabeth D. Williams, Michael R. Doran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platfor
Externí odkaz:
https://doaj.org/article/2f5eb33aec0547329c75ee64f3601dbc
Autor:
Darren Leahy, Cameron Grant, Alex Jackson, Alex Duff, Nicholas Tardiota, Jessica Van Haeften, Xingchen Chen, Jonathan M. Peake, Michael D. Kruppa, Eliot T. Smith, David A. Johnson, William B. Lott, Jonathan M. Harris
Publikováno v:
Molecules, Vol 26, Iss 17, p 5344 (2021)
Human neutrophil elastase (HNE) is a uniquely destructive serine protease with the ability to unleash a wave of proteolytic activity by destroying the inhibitors of other proteases. Although this phenomenon forms an important part of the innate immun
Externí odkaz:
https://doaj.org/article/06c08418647744e288d41d3b67a423b3
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202079 (2018)
A mathematical model was developed for mesenchymal stromal cell (MSC) growth in a packed bed bioreactor that improves oxygen availability by allowing oxygen diffusion through a gas-permeable wall. The governing equations for oxygen, glucose and lacta
Externí odkaz:
https://doaj.org/article/78537c0c3afd4673a095740902b93739
Autor:
David A. Johnson, Cameron Grant, Xingchen Chen, Alex Jackson, Eliot T Smith, William B. Lott, Jonathan M. Peake, Alex Duff, Michael D. Kruppa, Darren Leahy, Jonathan M. Harris, Jessica Van Haeften, Nicholas Tardiota
Publikováno v:
Molecules
Volume 26
Issue 17
Molecules, Vol 26, Iss 5344, p 5344 (2021)
Volume 26
Issue 17
Molecules, Vol 26, Iss 5344, p 5344 (2021)
Human neutrophil elastase (HNE) is a uniquely destructive serine protease with the ability to unleash a wave of proteolytic activity by destroying the inhibitors of other proteases. Although this phenomenon forms an important part of the innate immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9168b5096ff4616f8c7247707edcaca
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0122250 (2015)
We and others have published on the rapid manufacture of micropellet tissues, typically formed from 100-500 cells each. The micropellet geometry enhances cellular biological properties, and in many cases the micropellets can subsequently be utilized
Externí odkaz:
https://doaj.org/article/fca69fa74cdf4cd4a8a6fd7dd4ed4e91
Autor:
Md Abu Choudhury, William B Lott, Shahera Banu, Anthony Youzhi Cheng, Yik-Ying Teo, Rick Twee-Hee Ong, John Aaskov
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142473 (2015)
Dengue virus (DENV) populations are characteristically highly diverse. Regular lineage extinction and replacement is an important dynamic DENV feature, and most DENV lineage turnover events are associated with increased incidence of disease. The role
Externí odkaz:
https://doaj.org/article/e95bc840c3cb4330a5e9415381cec0e9
Autor:
Michael J Osiecki, Thomas D Michl, Betul Kul Babur, Mahboubeh Kabiri, Kerry Atkinson, William B Lott, Hans J Griesser, Michael R Doran
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144941 (2015)
Large numbers of Mesenchymal stem/stromal cells (MSCs) are required for clinical relevant doses to treat a number of diseases. To economically manufacture these MSCs, an automated bioreactor system will be required. Herein we describe the development
Externí odkaz:
https://doaj.org/article/e57d14b843ff4ac0aa9dc044fdbec3af
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107264 (2014)
Genetically diverse RNA viruses like dengue viruses (DENVs) segregate into multiple, genetically distinct, lineages that temporally arise and disappear on a regular basis. Lineage turnover may occur through multiple processes such as, stochastic or d
Externí odkaz:
https://doaj.org/article/de807441acfc40d4987d61beccf32c9b
Autor:
William B. Lott, Kathryn Futrega, Michael R. Doran, Ian Vela, Melissa E. Monterosso, Elizabeth D. Williams
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platform, the Mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53e6943fc0caf892acf9d0c213ab7d3
https://doi.org/10.1038/s41598-021-84154-4
https://doi.org/10.1038/s41598-021-84154-4
Publikováno v:
Nature.
Written grant proposals are inefficient to prepare and review, and scoring is notoriously unreliable. It’s time to consider audio-visual alternatives. Written grant proposals are inefficient to prepare and review, and scoring is notoriously unrelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d33fb917d829868b1d57553327423df2
https://doi.org/10.1038/d41586-021-00341-3
https://doi.org/10.1038/d41586-021-00341-3