Zobrazeno 1 - 2
of 2
pro vyhledávání: '"William B Fernandes"'
Autor:
Leandro A A Avelar, Cristian D Camilo, Sérgio de Albuquerque, William B Fernandes, Cristiana Gonçalez, Peter W Kenny, Andrei Leitão, James H McKerrow, Carlos A Montanari, Erika V Meñaca Orozco, Jean F R Ribeiro, Josmar R Rocha, Fabiana Rosini, Marta E Saidel
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003916 (2015)
A series of compounds based on the dipeptidyl nitrile scaffold were synthesized and assayed for their inhibitory activity against the T. cruzi cysteine protease cruzain. Structure activity relationships (SARs) were established using three, eleven and
Externí odkaz:
https://doaj.org/article/c07c0749619b40c0b5dab804ecd2bd13
Autor:
Helton J Wiggers, Josmar R Rocha, William B Fernandes, Renata Sesti-Costa, Zumira A Carneiro, Juliana Cheleski, Albérico B F da Silva, Luiz Juliano, Maria H S Cezari, João S Silva, James H McKerrow, Carlos A Montanari
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2370 (2013)
A multi-step cascade strategy using integrated ligand- and target-based virtual screening methods was developed to select a small number of compounds from the ZINC database to be evaluated for trypanocidal activity. Winnowing the database to 23 selec
Externí odkaz:
https://doaj.org/article/f12209661acd4a60a2472e7ba9b7fbeb