Zobrazeno 1 - 10
of 79
pro vyhledávání: '"William A. W. Walters"'
Publikováno v:
Australian and New Zealand Journal of Obstetrics and Gynaecology. 51:210-215
Background: There appears to be a rise in the rate of emergency peripartum hysterectomy (EPH) in the developed world. Aims: To determine the incidence, indications, risk factors, complications and management of EPH in our tertiary level teaching hosp
Publikováno v:
The Journal of Physiology. 569:903-912
Increased intrauterine prostaglandin (PG) production is crucial for the initiation of parturition. To investigate the mechanisms controlling intrauterine PG synthesis, we examined the expression of the key PG biosynthetic isoenzymes, PG-H2 synthase (
Publikováno v:
Placenta. 22:526-533
The effects of 8-epi-prostaglandin F(2alpha)(8-epi-PGF(2alpha)) and the thromboxane A(2)-mimetic U46619 were examined on isolated human fetal placental arteries obtained from normal pregnancies and from those complicated by pre-eclampsia. The effects
Autor:
Ian M. Leitch, M.A. Read, Roger Smith, Jacqueline F. Donoghue, A.L.A. Boura, William A. W. Walters, Warwick B. Giles
Publikováno v:
Placenta. 21:711-717
In this study, using the human placenta perfused in vitro with Krebs' bicarbonate solution, we have examined the effects of changes in oxygen tension on the vasoreactivity of fetal placental blood vessels to corticotropin releasing hormone (CRH). Vas
Publikováno v:
The Australian and New Zealand Journal of Obstetrics and Gynaecology. 39:401-410
Symptoms of normal pregnancy have received scant attention in the literature and what is reported is largely unsubstantiated. Yet this is an important aspect of antenatal counselling and care which deserves further investigation if symptoms are to be
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:4510-4513
Urocortin, is a recently isolated peptide belonging to the CRH family that binds with high affinity to the CRH2 receptor. Like CRH, urocortin causes hypotension in the rat, but its vasoactive actions have not yet been studied in the human. We have co
Publikováno v:
Hypertension in Pregnancy. 16:367-378
Objective: Reduced placental output of nitric oxide (NO) may contribute to increased vascular resistance and abnormally elevated corticotropin-releasing hormone (CRH) levels in umbilical cord plasma in pregnancies complicated by pregnancy-induced hyp
Publikováno v:
The Australian and New Zealand Journal of Obstetrics and Gynaecology. 36:267-271
The anticonvulsant magnesium and the antihypertensives clonidine and nifedipine are extensively used for the clinical treatment of preeclampsia and eclampsia. Little, however, is known about the possible effects of these agents on human fetal-placent
Autor:
William A. W. Walters, Nicholas A. Buckley, Anthony J. Smith, Jean McPherson, Lorraine Gallagher, Anne Mason
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 102:900-906
Objective By combining serial measurements of the circulating concentrations of thromboxane A, and prostacyclin with measurements of venous distensibility (taken during the pregnancies of both normal women and those with pregnancy induced hypertensio
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 21:737-748
SUMMARY 1. Humans have a haemochorial, villous placenta. Uterine blood passes through maternal sinuses, bathing placental villi through which fetal blood circulates. Blood flow through each circulation is high and vascular resistance low. This haemod