Zobrazeno 1 - 10
of 28
pro vyhledávání: '"William A. Segraves"'
Publikováno v:
Developmental Cell. 3:209-220
Isoform-specific null mutations were used to define the functions of three orphan members of the nuclear receptor superfamily, E75A, E75B, and E75C, encoded by the E75 early ecdysteroid-inducible gene. E75B mutants are viable and fertile, while E75C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07ad949b859f20006298debabcf4181
https://doi.org/10.1016/s1534-5807(02)00204-6
https://doi.org/10.1016/s1534-5807(02)00204-6
Autor:
Marianna Zinovjevna Kapitskaya, Alexander S. Raikhel, Ken Miura, Chao Li, Jinsong Zhu, William A. Segraves
Publikováno v:
Developmental Biology. 224:96-110
In the mosquito Aedes aegypti, the adult female becomes competent for a vitellogenic response to ecdysone after previtellogenic development. Here, we show that βFTZ-F1, the nuclear receptor implicated as a competence factor for stage-specific respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4366f9ab0942cddaf3c64c2d413bfaf9
https://doi.org/10.1006/dbio.2000.9792
https://doi.org/10.1006/dbio.2000.9792
Autor:
Chao Li, Alexander S. Raikhel, Ken Miura, Marianna Zinovjevna Kapitskaya, William A. Segraves
Publikováno v:
Molecular and Cellular Endocrinology. 160:25-37
The insect steroid hormone, 20-hydroxyecdysone (20E), is a key factor controlling critical developmental events of embryogenesis, larval molting, metamorphosis, and, in some insects, reproduction. We are interested in understanding the molecular basi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6497dd45b5c168bf3a9338cdb46db3e6
https://doi.org/10.1016/s0303-7207(99)00253-1
https://doi.org/10.1016/s0303-7207(99)00253-1
Publikováno v:
American Zoologist. 39:722-735
Synopsis. Vitellogenesis in insects involves the coordinated activity of the fat body, which produces large amounts of yolk protein precursors (YP), and oocytes, which specifically accumulate these proteins. The expression of YP genes is achieved thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d6447ca32b314d0e38752aebcf574a
https://doi.org/10.1093/icb/39.4.722
https://doi.org/10.1093/icb/39.4.722
Autor:
Ken Miura, Alexander S. Raikhel, Chao Li, William A. Segraves, William E. Pierceall, Avraham Biran
Publikováno v:
Molecular and Cellular Endocrinology. 150:73-89
The steroid hormone ecdysone controls genetic regulatory hierarchies underlying insect molting, metamorphosis and, in some insects, reproduction. Cytogenetic and molecular analysis of ecdysone response in Drosophila larval salivary glands has reveale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb6afddae93cedfd36b581e658c4fda
https://doi.org/10.1016/s0303-7207(99)00022-2
https://doi.org/10.1016/s0303-7207(99)00022-2
Autor:
William A. Segraves
Publikováno v:
Seminars in Cell Biology. 5:105-113
Drosophila steroid receptors and related receptor-like proteins show remarkable conservation of structure and function relative to vertebrate homologues. While those proteins are involved in numerous embryonic and post-embryonic developmental process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f6f3bbad03c01ed0d712a42eb6f623
https://doi.org/10.1006/scel.1994.1014
https://doi.org/10.1006/scel.1994.1014
Autor:
Christine Woldin, William A. Segraves
Publikováno v:
Insect Biochemistry and Molecular Biology. 23:91-97
The ecdysone-inducible E75 gene responsible for the 75B puff of Drosophila melanogaster encodes a family of proteins which are members of the steroid receptor superfamily. These proteins are believed to be involved in the regulation of ecdysone respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c676504e5afd488c499694bc14584f
https://doi.org/10.1016/0965-1748(93)90086-8
https://doi.org/10.1016/0965-1748(93)90086-8
Publikováno v:
Proceedings of the National Academy of Sciences. 89:6167-6171
In Drosophila the steroid hormone ecdysone triggers a genetic regulatory hierarchy in which ecdysone combines with a receptor protein to form a complex that induces the transcription of a small class of "early" genes, which encode transcription facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db132d590070bb8d6a4d9fda9fbb713
https://doi.org/10.1073/pnas.89.13.6167
https://doi.org/10.1073/pnas.89.13.6167
Autor:
William A. Segraves, Geoff Richards
Publikováno v:
Invertebrate Reproduction & Development. 18:67-76
Summary The IXth Ecdysone Workshop marked a turning point in studies of ecdysone and gene regulation, as there has been significant progress in our understanding both of the regulatio9n and function of ecdysone-inducible genes. A number of reports co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35086c8c4045e8c67ef62909d681a45c
https://doi.org/10.1080/07924259.1990.9672129
https://doi.org/10.1080/07924259.1990.9672129
Autor:
David S. Hogness, William A. Segraves
Publikováno v:
Genes & Development. 4:204-219
A pulse of the steroid hormone ecdysone at the end of Drosophila larval development triggers coordinate changes in both larval and imaginal tissues that result in metamorphosis to the adult fly. In larval salivary glands, this pulse activates a genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd906b749d3fc96128a7548168633f5
https://doi.org/10.1101/gad.4.2.204
https://doi.org/10.1101/gad.4.2.204