Zobrazeno 1 - 10
of 964
pro vyhledávání: '"William A. Russell"'
Autor:
Ravi R. Sonani, Lee K. Palmer, Nathaniel C. Esteves, Abigail A. Horton, Amanda L. Sebastian, Rebecca J. Kelly, Fengbin Wang, Mark A. B. Kreutzberger, William K. Russell, Petr G. Leiman, Birgit E. Scharf, Edward H. Egelman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract A contractile sheath and rigid tube assembly is a widespread apparatus used by bacteriophages, tailocins, and the bacterial type VI secretion system to penetrate cell membranes. In this mechanism, contraction of an external sheath powers the
Externí odkaz:
https://doaj.org/article/8ffa8b55ddc8423ca2316eb1e94a3daa
Autor:
Henock M. Deberneh, Doaa R. Abdelrahman, Sunil K. Verma, Jennifer J. Linares, Andrew J. Murton, William K. Russell, Muge N. Kuyumcu-Martinez, Benjamin F. Miller, Rovshan G. Sadygov
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract Metabolic stable isotope labeling with heavy water followed by liquid chromatography coupled with mass spectrometry (LC-MS) is a powerful tool for in vivo protein turnover studies. Several algorithms and tools have been developed to determin
Externí odkaz:
https://doaj.org/article/0900532a627d440b99e27ccff0f8914b
Autor:
Henock M. Deberneh, Doaa R. Abdelrahman, Sunil K. Verma, Jennifer J. Linares, Andrew J. Murton, William K. Russell, Muge N. Kuyumcu-Martinez, Benjamin F. Miller, Rovshan G. Sadygov
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Heavy water metabolic labeling followed by liquid chromatography coupled with mass spectrometry is a powerful high throughput technique for measuring the turnover rates of individual proteins in vivo. The turnover rate is obtained from the e
Externí odkaz:
https://doaj.org/article/2fd9fe96ab7f42029f30a4b802d31e12
Autor:
Myriah L. Acuña, Andrea García-Morin, Rebeca Orozco-Sepúlveda, Carlos Ontiveros, Alejandra Flores, Arely V. Diaz, Isabel Gutiérrez-Zubiate, Abhijeet R. Patil, Luis A. Alvarado, Sourav Roy, William K. Russell, Germán Rosas-Acosta
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-24 (2023)
Abstract Substantial increases in the conjugation of the main human SUMO paralogs, SUMO1, SUMO2, and SUMO3, are observed upon exposure to different cellular stressors, and such increases are considered important to facilitate cell survival to stress.
Externí odkaz:
https://doaj.org/article/f7f21198a0ec44db8146fd2e31608b84
Autor:
Wenhui Wu, Jeong Seon Kim, Aaron O. Bailey, William K. Russell, Stephen J. Richards, Tiantian Chen, Tingfei Chen, Zhenhang Chen, Bo Liang, Mitsuo Yamauchi, Houfu Guo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Humans and Acanthamoeba polyphaga mimivirus share numerous homologous genes, including collagens and collagen-modifying enzymes. To explore this homology, we performed a genome-wide comparison between human and mimivirus using DELTA-BLAST (D
Externí odkaz:
https://doaj.org/article/cb6af35921514888996b0d19a1c51b8e
Autor:
Lauren G. Mascibroda, Mohammad Shboul, Nathan D. Elrod, Laurence Colleaux, Hanan Hamamy, Kai-Lieh Huang, Natoya Peart, Moirangthem Kiran Singh, Hane Lee, Barry Merriman, Jeanne N. Jodoin, Poojitha Sitaram, Laura A. Lee, Raja Fathalla, Baeth Al-Rawashdeh, Osama Ababneh, Mohammad El-Khateeb, Nathalie Escande-Beillard, Stanley F. Nelson, Yixuan Wu, Liang Tong, Linda J. Kenney, Sudipto Roy, William K. Russell, Jeanne Amiel, Bruno Reversade, Eric J. Wagner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The integrator complex is required for the synthesis of protein coding and non-coding RNA and contains the protein INTS13. Here, the authors find germline mutations in INTS13 in two families with oral facial digital syndrome and show that the mutatio
Externí odkaz:
https://doaj.org/article/35883c108c1d4e72ba468a3fd1444767
Autor:
Xiaochao Tan, Guan-Yu Xiao, Shike Wang, Lei Shi, Yanbin Zhao, Xin Liu, Jiang Yu, William K. Russell, Chad J. Creighton, Jonathan M. Kurie
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Hypersecretory malignant cells underlie therapeutic resistance, metastasis, and poor clinical outcomes. However, the molecular basis for malignant hypersecretion remains obscure. Here, we showed that epithelial-mesenchymal transition (EMT) initiates
Externí odkaz:
https://doaj.org/article/bf7521c5ce53496a9c18099d6e3fb8f7
Autor:
Priyam Banerjee, Guan-Yu Xiao, Xiaochao Tan, Veronica J. Zheng, Lei Shi, Maria Neus Bota Rabassedas, Hou-fu Guo, Xin Liu, Jiang Yu, Lixia Diao, Jing Wang, William K. Russell, Jason Roszik, Chad J. Creighton, Jonathan M. Kurie
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The way in which metastatic tumour cells control endocytic vesicular trafficking networks to establish a front-rear polarity axis that facilitates motility remains unclear. Here, the authors show that the EMT activator ZEB1 influences vesicular traff
Externí odkaz:
https://doaj.org/article/f1d2c3cc69384dc7bdd8b00a1be1cda5
Autor:
Evagelia C. Laiakis, Maisa Pinheiro, Tin Nguyen, Hung Nguyen, Afshin Beheshti, Sucharita M. Dutta, William K. Russell, Mark R. Emmett, Richard A. Britten
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
NASA’s planned mission to Mars will result in astronauts being exposed to ∼350 mSv/yr of Galactic Cosmic Radiation (GCR). A growing body of data from ground-based experiments indicates that exposure to space radiation doses (approximating those t
Externí odkaz:
https://doaj.org/article/b5001e1d600844f98944e471e71838fd
Autor:
Selorm A. Dei-Tutu, Adoma Manful, Douglas C. Heimburger, Hawa Malechi, Daniel J. Moore, Samuel A. Oppong, William E. Russell, Muktar H. Aliyu
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Congenital hypothyroidism is a common, yet easily treatable cause of poor growth and intellectual disability. Newborn screening programs play an important role in the early detection and treatment of congenital hypothyroidism. How
Externí odkaz:
https://doaj.org/article/d1fd85f31c39404baa8f15d228c6e1f9