Zobrazeno 1 - 10
of 42
pro vyhledávání: '"William A. Rosche"'
Publikováno v:
Journal of Bacteriology. 186:3270-3273
A temperate, type IV pilus-dependent, double-stranded DNA bacteriophage named DMS3 was isolated from a clinical strain of Pseudomonas aeruginosa . A clear-plaque variant of this bacteriophage was isolated. DMS3 is capable of mediating generalized tra
Publikováno v:
Trends in Genetics, 19, 365-369
Trends in Genetics, 19, 7, pp. 365-369
Trends in Genetics, 19, 7, pp. 365-369
Quasipalindromes, or imperfect inverted repeats, undergo spontaneous mutation to more-perfect inverted repeats. These mutations have been observed in many organisms, ranging from bacteria to humans, where they are associated with mutations leading to
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 502:39-46
Escherichia coli has provided an important model system for understanding the molecular basis for genetic instabilities associated with repeated DNA. Changes in triplet repeat length during growth following transformation in E. coli have been used as
Publikováno v:
Journal of Biological Chemistry. 275:2174-2184
The influence of mutations in the 3' to 5' exonucleolytic proofreading epsilon-subunit of Escherichia coli DNA polymerase III on the genetic instabilities of the CGG.CCG and the CTG.CAG repeats that cause human hereditary neurological diseases was in
Autor:
Patricia L. Foster, William A. Rosche
Publikováno v:
Proceedings of the National Academy of Sciences. 96:6862-6867
Microbial populations under nonlethal selection can give rise to mutations that relieve the selective pressure, a phenomenon that has come to be called “adaptive mutation.” One explanation for adaptive mutation is that a small proportion of the c
Autor:
Patricia L. Foster, William A. Rosche
Publikováno v:
Genetics. 152:15-30
Adaptive mutation has been studied extensively in FC40, a strain of Escherichia coli that cannot metabolize lactose (Lac-) because of a frameshift mutation affecting the lacZ gene on its episome. recD mutants of FC40, in which the exonuclease activit
Publikováno v:
Annals of the New York Academy of Sciences. 870:173-189
The fidelity of replication has evolved to reproduce B-form DNA accurately, while allowing a low frequency of mutation. The fidelity of replication can be compromised, however, by defined order sequence DNA (dosDNA) that can adopt unusual or non B-DN
Autor:
Patricia L. Foster, William A. Rosche
Publikováno v:
Journal of Genetics. 78:7-11
Mutations can arise in static populations of cells that are subjected to nonlethal selective pressure, a phenomenon that has been called ‘adaptive mutation’. This phenomenon has been extensively studied in FC40, a strain ofEscherichia coli that c
Publikováno v:
Journal of Molecular Biology. 264:82-96
Instabilities that are intrinsic to natural repetitive DNA sequences produce high frequencies of length changes in vivo. Triplet repeats cloned in plasmids in Escherichia coli undergo expansions and deletions, and this instability is affected by mult
Autor:
William A. Rosche, Patricia L. Foster
Publikováno v:
Journal of Bacteriology. 180:1944-1946
Vsr endonuclease, which initiates very short patch repair, has been hypothesized to regulate mutation in stationary-phase cells. Overexpression of Vsr does dramatically increase the stationary-phase reversion of a Lac − frameshift allele, but the a