Specific Cryptosporidium antigens associate with reinfection immunity and protection from cryptosporidiosis

Autor: Carol A. Gilchrist, Joseph J. Campo, Jozelyn V. Pablo, Jennie Z. Ma, Andy Teng, Amit Oberai, Adam D. Shandling, Masud Alam, Mamun Kabir, A.S.G. Faruque, Rashidul Haque, William A. Petri Jr.

Publikováno v: The Journal of Clinical Investigation, Vol 133, Iss 16 (2023)

There is no vaccine to protect from cryptosporidiosis, a leading cause of diarrhea in infants in low- and middle-income countries. Here, we comprehensively identified parasite antigens associated with protection from reinfection. A Cryptosporidium pr

Externí odkaz: https://doaj.org/article/02afb00b6ae54b5eb3845685dd07d781

Microbiota-Regulated IL-25 Increases Eosinophil Number to Provide Protection during Clostridium difficile Infection

Autor: Erica L. Buonomo, Carrie A. Cowardin, Madeline G. Wilson, Mahmoud M. Saleh, Patcharin Pramoonjago, William A. Petri Jr.

Publikováno v: Cell Reports, Vol 16, Iss 2, Pp 432-443 (2016)

Clostridium difficile infection (CDI) is the most common cause of hospital-acquired infection in the United States. Host susceptibility and the severity of infection are influenced by disruption of the microbiota and the immune response. However, how

Externí odkaz: https://doaj.org/article/b0629d5debc54cc69b7a02c215a85d41

Causal Pathways from Enteropathogens to Environmental Enteropathy: Findings from the MAL-ED Birth Cohort Study

Autor: Margaret N. Kosek, Tahmeed Ahmed, Zulfiquar Bhutta, Laura Caulfield, Richard Guerrant, Eric Houpt, Gagandeep Kang, Margaret Kosek, Gwenyth Lee, Aldo Lima, Benjamin J.J. McCormick, James Platts-Mills, Jessica Seidman, Rebecca R. Blank, Michael Gottlieb, Stacey L. Knobler, Dennis R. Lang, Mark A. Miller, Karen H. Tountas, Zulfiqar A. Bhutta, William Checkley, Richard L. Guerrant, Carl J. Mason, Laura E. Murray-Kolb, William A. Petri, Jr., Jessica C. Seidman, Pascal Bessong, Rashidul Haque, Sushil John, Aldo A.M. Lima, Estomih R. Mduma, Reinaldo B. Oriá, Prakash Sunder Shrestha, Sanjaya Kumar Shrestha, Erling Svensen, Anita K.M. Zaidi, Cláudia B. Abreu, Angel Mendez Acosta, Imran Ahmed, A.M. Shamsir Ahmed, Asad Ali, Ramya Ambikapathi, Leah Barrett, Aubrey Bauck, Eliwaza Bayyo, Ladaporn Bodhidatta, Anuradha Bose, J. Daniel Carreon, Ram Krishna Chandyo, Vivek Charu, Hilda Costa, Rebecca Dillingham, Alessandra Di Moura, Viyada Doan, Jose Quirino Filho, Jhanelle Graham, Christel Hoest, Iqbal Hossain, Munirul Islam, M. Steffi Jennifer, Shiny Kaki, Beena Koshy, Álvaro M. Leite, Noélia L. Lima, Bruna L.L. Maciel, Mustafa Mahfuz, Cloupas Mahopo, Angelina Maphula, Monica McGrath, Archana Mohale, Milena Moraes, Francisco S. Mota, Jayaprakash Muliyil, Regisiana Mvungi, Gaurvika Nayyar, Emanuel Nyathi, Maribel Paredes Olortegui, Reinaldo Oria, Angel Orbe Vasquez, William K. Pan, John Pascal, Crystal L. Patil, Laura Pendergast, Silvia Rengifo Pinedo, Stephanie Psaki, Mohan Venkata Raghava, Karthikeyan Ramanujam, Muneera Rasheed, Zeba A. Rasmussen, Stephanie A. Richard, Anuradha Rose, Reeba Roshan, Barbara Schaefer, Rebecca Scharf, Srujan L. Sharma, Binob Shrestha, Rita Shrestha, Suzanne Simons, Alberto M. Soares, Rosa M.S. Mota, Sajid Soofi, Tor Strand, Fahmida Tofail, Rahul J. Thomas, Ali Turab, Manjeswori Ulak, Vivian Wang, Ladislaus Yarrot, Pablo Peñataro Yori, Didar Alam, Caroline Amour, Cesar Banda Chavez, Sudhir Babji, Rosa Rios de Burga, Julian Torres Flores, Jean Gratz, Ajila T. George, Dinesh Hariraju, Alexandre Havt, Priyadarshani Karunakaran, Robin P. Lazarus, Ila F. Lima, Dinesh Mondal, Pedro H.Q.S. Medeiros, Rosemary Nshama, Josiane Quetz, Shahida Qureshi, Sophy Raju, Anup Ramachandran, Rakhi Ramadas, A. Catharine Ross, Mery Siguas Salas, Amidou Samie, Kerry Schulze, E. Shanmuga Sundaram, Buliga Mujaga Swema, Dixner Rengifo Trigoso

Publikováno v: EBioMedicine, Vol 18, Iss C, Pp 109-117 (2017)

Background: Environmental enteropathy (EE), the adverse impact of frequent and numerous enteric infections on the gut resulting in a state of persistent immune activation and altered permeability, has been proposed as a key determinant of growth fail

Externí odkaz: https://doaj.org/article/c3ea0668870d4a51b813fae7c0c03278

Amebiasis

Autor: A Bhattacharya, D Campbell, M Espinosa Cantellano, Kris Chadee, C Graham Clark, T F Jackson, K C Kain, J S Keystone, David Mirelman, D R Pillai, Girija Ramakrishan, Jonathan I Ravdin, S L Reed, Samuel L Stanley Jr, William A Petri Jr

Amebiasis presents the most up-to-date overview of the field, encompassing all aspects of epidemiology, clinical management, and research. The most authoritative physicians and scientists worldwide have contributed to this effort. Future research dir

Global disability-adjusted life-year estimates of long-term health burden and undernutrition attributable to diarrhoeal diseases in children younger than 5 years

Autor: Christopher Troeger, MPH, Danny V Colombara, PhD, Puja C Rao, MPH, Ibrahim A Khalil, MD, Alexandria Brown, MA, Thomas G Brewer, MD, Richard L Guerrant, MD, Eric R Houpt, MD, Karen L Kotloff, ProfMD, Kavita Misra, PhD, William A Petri, Jr, MD, James Platts-Mills, MD, Mark S Riddle, MD, Scott J Swartz, MS, Mohammad H Forouzanfar, MD, Robert C Reiner, Jr, PhD, Simon I Hay, ProfFMedSci, Ali H Mokdad, ProfPhD

Publikováno v: The Lancet Global Health, Vol 6, Iss 3, Pp e255-e269 (2018)

Summary: Background: Diarrhoea is a leading cause of death and illness globally among children younger than 5 years. Mortality and short-term morbidity cause substantial burden of disease but probably underestimate the true effect of diarrhoea on pop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::e77ec3f5d23f78d16d3fef0de0788780
http://www.sciencedirect.com/science/article/pii/S2214109X18300457