Výsledky vyhledávání - "William A. Pace"

Akademický článek

Development and characterization of an intra‐articular fracture mediated model of post‐traumatic osteoarthritis

Autor: Michael S. Valerio, William A. Pace, Connor P. Dolan, Jorge B. Edwards, Naveena B. Janakiram, Benjamin K. Potter, Christopher L. Dearth, Stephen M. Goldman

Publikováno v: Journal of Experimental Orthopaedics, Vol 10, Iss 1, Pp n/a-n/a (2023)

Abstract Purpose This study aimed to develop and characterize a closed intra‐articular fracture (IAF) mediated post‐traumatic osteoarthritis (PTOA) model in rats to serve as a testbed for putative disease modifying interventions. Methods Male rat

Externí odkaz: https://doaj.org/article/1e4fcf24e98346fcb7327fb4551df014

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Akademický článek

Pharmacological blockade of the EP3 prostaglandin E2 receptor in the setting of type 2 diabetes enhances β-cell proliferation and identity and relieves oxidative damage

Autor: Karin J. Bosma, Spencer R. Andrei, Liora S. Katz, Ashley A. Smith, Jennifer C. Dunn, Valerie F. Ricciardi, Marisol A. Ramirez, Sharon Baumel-Alterzon, William A. Pace, Darian T. Carroll, Emily M. Overway, Elysa M. Wolf, Michelle E. Kimple, Quanhu Sheng, Donald K. Scott, Richard M. Breyer, Maureen Gannon

Publikováno v: Molecular Metabolism, Vol 54, Iss , Pp 101347- (2021)

Objective: Type 2 diabetes is characterized by hyperglycemia and inflammation. Prostaglandin E2, which signals through four G protein-coupled receptors (EP1-4), is a mediator of inflammation and is upregulated in diabetes. We have shown previously th

Externí odkaz: https://doaj.org/article/938250ff8f6d4937886d25473129e45f

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Pharmacological blockade of the EP3 prostaglandin E2 receptor in the setting of type 2 diabetes enhances β-cell proliferation and identity and relieves oxidative damage

Autor: Liora S. Katz, Donald K. Scott, William A. Pace, Maureen Gannon, Richard M. Breyer, Elysa M. Wolf, Michelle E. Kimple, Karin J. Bosma, Ashley A. Smith, Valerie F. Ricciardi, Darian T. Carroll, Quanhu Sheng, Jennifer C. Dunn, Spencer R. Andrei, Sharon Baumel-Alterzon, Marisol A. Ramirez, Emily M. Overway

Publikováno v: Molecular Metabolism, Vol 54, Iss, Pp 101347-(2021)
Molecular Metabolism

Objective Type 2 diabetes is characterized by hyperglycemia and inflammation. Prostaglandin E2, which signals through four G protein-coupled receptors (EP1-4), is a mediator of inflammation and is upregulated in diabetes. We have shown previously tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06e0b046831955a56ff09322b5523b4
http://www.sciencedirect.com/science/article/pii/S2212877821001940

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2064-P: Pharmacological Modulation of Prostaglandin E2 Receptor Activity Enhances ß-Cell Mass and Maintains ß-Cell Identity in a Mouse Model of Type 2 Diabetes

Autor: Ashley A. Christensen, Spencer R. Andrei, William A. Pace, Jennifer C. Dunn, Richard M. Breyer, Maureen Gannon, Valerie F. Ricciardi

Publikováno v: Diabetes. 69

Type 2 diabetes (T2D) is a chronic condition characterized by hyperglycemia and inflammation. This condition arises in response to a failure to increase β-cell mass in the face of insulin resistance. Prostaglandin E2 (PGE2), which signals through fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acfc4112a59f2a1c66dd46206c8b2422
https://doi.org/10.2337/db20-2064-p

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196-OR: Pharmacological Modulation of Prostaglandin E2 Receptor Activity Enhances ß-Cell Mass in a Mouse Model of Type 2 Diabetes and Human Islets

Autor: Richard M. Breyer, Valerie F. Ricciardi, William A. Pace, Ashley A. Christensen, Jennifer C. Dunn, Maureen Gannon, Spencer R. Andrei

Publikováno v: Diabetes. 68

Type 2 diabetes (T2D) is characterized by chronic hyperglycemia and low-grade inflammation. Failure to expand β-cell mass in response to insulin resistance can lead to T2D. The hyperglycemia and chronic inflammation observed in T2D is associated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::125d0248488f4b7a661692fcf2ef56d9
https://doi.org/10.2337/db19-196-or

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A Redesigned Engagement and Recruitment Strategy forEngineering Technology Programs at a Regional Campus

Autor: Megan E. Prygoski, Gene L. Harding, Randall J. Budreau, William M. Pace, John A. Piller, James D. Burns

Publikováno v: ASEE IL-IN Section Conference

While enrollment in engineering programs is generally strong nationwide, maintaining or increasing enrollment in Engineering Technology programs at smaller regional campuses can be challenging. The problem appears to be multi-faceted, with the rising

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01c51cf6ccb31f03a58a5becfd0889d
https://docs.lib.purdue.edu/aseeil-insectionconference/2018/transf/1

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