Zobrazeno 1 - 10
of 2 210
pro vyhledávání: '"William A. Murphy"'
Autor:
William A. Murphy, Anna Mae Diehl, Matthew Shane Loop, Dong Fu, Cynthia D. Guy, Manal F. Abdelmalek, Georgia Sofia Karachaliou, Noora Sjöstedt, Sibylle Neuhoff, Paavo Honkakoski, Kim L. R. Brouwer
Publikováno v:
Hepatology Communications, Vol 8, Iss 3 (2024)
Background:. NAFLD is highly prevalent with limited treatment options. Bile acids (BAs) increase in the systemic circulation and liver during NAFLD progression. Changes in plasma membrane localization and zonal distribution of BA transporters can inf
Externí odkaz:
https://doaj.org/article/aac573e3c0734319af4532863a1f9a55
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 128-132 (2020)
Introduction: Immune checkpoint inhibitors (ICIs) are often associated with inflammatory toxicities known as immune-related adverse events (irAEs). Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is an atypical inflammatory ar
Externí odkaz:
https://doaj.org/article/8a04eb7df57142d08870123cc02d64e1
Publikováno v:
Bone Reports, Vol 5, Iss , Pp 163-167 (2016)
Because of the increasing trend of body contour enhancements with injections, implants, and fillers, clinicians should be on high alert for the possibility of silicone-induced hypercalcemia as one of the differential diagnoses in a patient with histo
Externí odkaz:
https://doaj.org/article/b2935cdb201e407191ee31866331390d
Autor:
Nian Jiang, Bowen Xie, Wenwu Xiao, Ming Fan, Shanxiu Xu, Yixin Duan, Yamah Hamsafar, Angela C. Evans, Jie Huang, Weibing Zhou, Xuelei Lin, Ningrong Ye, Siyi Wanggou, Wen Chen, Di Jing, Ruben C. Fragoso, Brittany N. Dugger, Paul F. Wilson, Matthew A. Coleman, Shuli Xia, Xuejun Li, Lun-Quan Sun, Arta M. Monjazeb, Aijun Wang, William J. Murphy, Hsing-Jien Kung, Kit S. Lam, Hong-Wu Chen, Jian Jian Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Acquired radioresistance is a challenge for the cure of glioblastoma. Here, the authors show that radioresistant glioblastoma boosts mitochondrial fatty acid oxidation that fuels cell proliferation and induces immunosuppression via CD47 mediated anti
Externí odkaz:
https://doaj.org/article/9ea4ad505be945a8af46118fb26c43d3
Autor:
Susan L Stewart, William J Murphy, Robert J Canter, Cordelia Dunai, Ellen E Sparger, Michael S Kent, Sean J Judge, Alicia A Gingrich, Robert B Rebhun, Daniel York, Sylvia Margret Cruz, Aryana M Razmara, Lauren E Farley, Rachel V Brady, Eric G Johnson, Jenna H Burton, Jennifer Willcox, Luke A Wittenburg, Kevin Woolard, Sita S Withers, Katherine A Skorupski, Sami Al-Nadaf, Amandine T LeJeune, William TN Culp
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/b7909ec5216c40509e05a8b62eafd4c7
Autor:
Alexandra N Myers, Sara D Lawhon, Alison B Diesel, Charles W Bradley, Aline Rodrigues Hoffmann, William J Murphy, Lives Cat Genome Consortium
Publikováno v:
PLoS Genetics, Vol 18, Iss 2, p e1010062 (2022)
Dermatophytosis, also known as ringworm, is a contagious fungal skin disease affecting humans and animals worldwide. Persian cats exhibit severe forms of the disease more commonly than other breeds of cat, including other long-haired breeds. Certain
Externí odkaz:
https://doaj.org/article/b774b170c44b42cc8d95364f1ec2561e
Autor:
Gianluca Fontana, Hannah L. Martin, Jae Sung Lee, Kristen Schill, Peiman Hematti, William L. Murphy
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 455-464 (2019)
The regenerative potential of bone marrow cells could be harnessed for tissue engineering applications. Bone marrow can be easily collected from patients, providing a valuable autologous source of therapeutic cells. However, years of delivery of bone
Externí odkaz:
https://doaj.org/article/c68b178531eb42019ad50b72cd9d1dba
Autor:
Catherine T. Le, William J. Murphy
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-5 (2019)
Abstract The tremendous clinical success of immune checkpoint inhibition (ICI), particularly targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1/2 (PD-L1/2) pathway, has resulted in application to multiple cancers, as a mon
Externí odkaz:
https://doaj.org/article/b256ebe432a74d7fa6d073e20ef2837b
Autor:
Pengfei Xu, Logan J. Wasielewski, Joy C. Yang, Demin Cai, Christopher P. Evans, William J. Murphy, Chengfei Liu
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1778 (2022)
Prostate cancer is one of the most common malignant tumors in men. Initially, it is androgen-dependent, but it eventually develops into castration-resistant prostate cancer (CRPC), which is incurable with current androgen receptor signaling target th
Externí odkaz:
https://doaj.org/article/3a3654ce0e524217895a066031c11c82
Autor:
Daniel J. Hellenbrand, Kaitlyn A. Reichl, Benjamin J. Travis, Mallory E. Filipp, Andrew S. Khalil, Domenic J. Pulito, Ashley V. Gavigan, Elizabeth R. Maginot, Mitchell T. Arnold, Alexander G. Adler, William L. Murphy, Amgad S. Hanna
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Abstract Background The anti-inflammatory cytokine interleukin-10 (IL-10) has been explored previously as a treatment method for spinal cord injury (SCI) due to its ability to attenuate pro-inflammatory cytokines and reduce apoptosis. Primary limitat
Externí odkaz:
https://doaj.org/article/10bb43dc4ae14a92b90d7a8dfada947c