Zobrazeno 1 - 10
of 16
pro vyhledávání: '"William A. Dittman"'
Autor:
William A. Dittman
Publikováno v:
Trends in Cardiovascular Medicine. 1:331-336
Thrombomodulin on endothelial surfaces is the major cofactor for the activation of the anticoagulant protein C by thrombin. Recent studies of the structure and regulation of thrombomodulin provide important clues as to its mechanism of action. These
Autor:
William A. Dittman, Mitsuhiro Osame, Takahiko Ito, Hidehiko Saito, Yasuko Soejima, Ikuro Maruyama, Kohei Ogawa, Shuji Yamamoto
Publikováno v:
Thrombosis Research. 61:301-310
We previously reported that the expression of thrombomodulin on the MEG-01, a cell line from human megakaryoblastic leukemia, was increased by agents that increase intracellular cAMP. In this paper we examine the effect of these agents on cultured hu
Autor:
William A. Dittman, Philip W. Majerus
Publikováno v:
Blood. 75:329-336
Publikováno v:
Human pathology. 31(3)
Transient myeloproliferative disease (TMD) of the newborn is a rare hematologic abnormality associated with trisomy 21. It is frequently difficult to distinguish the disorder from true congenital leukemia (TCL). Unlike leukemia, which has a clinicall
Autor:
Danial E. Baker, Christopher M. Starr, William A. Dittman, Gordon Ens, John C. Klock, Lyle D. Broemeling, Marcia R. Mielke, John R. White, Matt Wacksman, Sylvia A. Oliver, Dawn Devereaux, Patrick R. Gavin, C. Harold Mielke
Publikováno v:
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 5(4)
A number of investigations have noted that func tional biological assays for heparin are not always reliable and may not reflect the actual biochemical level of heparin in pa tients receiving anticoagulant therapy. This creates the possi bility that
Autor:
William A. Dittman
Publikováno v:
Blood. 122:4732-4732
Context Pyknotic lymphocytes were infrequently observed in routine blood film evaluation of patients with clinical infectious mononucleosis. A marked increase in frequency was observed in 1995-1997. Objective To characterize the cause of these change
Publikováno v:
Biochemistry. 29(47)
Thrombomodulin is an endothelial cell surface receptor for thrombin that acts as a physiological anticoagulant. The properties of recombinant human thrombomodulin were studied in COS-7, CHO, CV-1, and K562 cell lines. Thrombomodulin was expressed on
Publikováno v:
Journal of Biological Chemistry. 263:15815-15822
Thrombomodulin is an endothelial membrane anticoagulant protein that is a cofactor for protein C activation. We have evaluated the expression of thrombomodulin in cultured mouse hemangioma cells before and after treatment with phorbol myristate aceta
Autor:
William I. Dittman, Anatolio B. Cruz, Robert P. Saylor, Lynn H. Banowsky, Michael F. Sarosdy, Harold V. Gaskill
Publikováno v:
Urology. 26(4)
Upper gastrointestinal bleeding has been shown to be a common complication of renal transplantation and one which carries a significant risk of mortality. In a retrospective review of 200 consecutive renal transplants in 194 patients, we found an inc
Autor:
William A. Dittman, Philip W. Majerus
Publikováno v:
Nucleic acids research. 17(2)
Thrombomodulin is an endothelial cell surface anticoagulant cofactor for activation of the serum protease protein C. The authors have previously described a complete cDNA for human thrombomodulin, and a partial cDNA for mouse thrombomodulin. They now