Zobrazeno 1 - 10
of 231
pro vyhledávání: '"William A. Brownell"'
Autor:
Tetsuji Yamashita, Pierre Hakizimana, Siva Wu, Ahmed Hassan, Stefan Jacob, Jamshid Temirov, Jie Fang, Marcia Mellado-Lagarde, Richard Gursky, Linda Horner, Barbara Leibiger, Sara Leijon, Victoria E Centonze, Per-Olof Berggren, Sharon Frase, Manfred Auer, William E Brownell, Anders Fridberger, Jian Zuo
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005500 (2015)
Nature's fastest motors are the cochlear outer hair cells (OHCs). These sensory cells use a membrane protein, Slc26a5 (prestin), to generate mechanical force at high frequencies, which is essential for explaining the exquisite hearing sensitivity of
Externí odkaz:
https://doaj.org/article/ae9f8a167b014b09ac6113b4a1b70ee8
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57147 (2013)
Protrusions are deformations that form at the surface of living cells during biological activities such as cell migration. Using combined optical tweezers and fluorescent microscopy, we quantified the mechanical properties of protrusions in adherent
Externí odkaz:
https://doaj.org/article/6ee27c2f6e1a443cb438e71df754404c
Publikováno v:
The Journal of General Physiology
By comparing the measured displacement charge with a voltage-sensing model, Farrell et al. identify two hyperpolarized states and two reaction pathways in OHCs, suggesting that multiple pathways may allow these cells to amplify acoustic vibrations th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f78cc5323e488fe95151112743ade7
https://doi.org/10.1085/jgp.201912447
https://doi.org/10.1085/jgp.201912447
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37667 (2012)
The membrane protein prestin is native to the cochlear outer hair cell that is crucial to the ear's amplification and frequency selectivity throughout the whole acoustic frequency range. The outer hair cell exhibits interrelated dimensional changes,
Externí odkaz:
https://doaj.org/article/577fe455cf5f42f1a052e620b27ce652
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 7, p e1000444 (2009)
Cochlear outer hair cells (OHCs) are fast biological motors that serve to enhance the vibration of the organ of Corti and increase the sensitivity of the inner ear to sound. Exactly how OHCs produce useful mechanical power at auditory frequencies, gi
Externí odkaz:
https://doaj.org/article/a9930b898a3a49488895efd190577e3b
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5201 (2009)
Microvilli (stereocilia) projecting from the apex of hair cells in the inner ear are actively motile structures that feed energy into the vibration of the inner ear and enhance sensitivity to sound. The biophysical mechanism underlying the hair bundl
Externí odkaz:
https://doaj.org/article/aab1c11a3ad14d7394232b91d3b3e087
Autor:
Dmitri A. Tsyboulski, Neil Ball, Paolo Bianchini, Natalia Orlova, Gaddum D. Reddy, Vijay Iyer, James Brockill, William E. Brownell, Olga Gliko, James R. Cotton, Andreas S. Tolias, Alberto Diaspro, Martí Duocastella, Peter Saggau
Publikováno v:
Fourteenth School on Acousto-Optics and Applications.
This review presents a selection of advanced microscope designs employing acousto-optical deflectors (AODs). In the designs covered, AODs are used as tunable diffraction gratings to control complex illumination patterns at the Fourier plane of an obj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c77990d7e0dd9b4dd4f378dcd1c8b78b
https://doi.org/10.1117/12.2538419
https://doi.org/10.1117/12.2538419
Publikováno v:
Biophysical journal. 114(11)
The organization of the plasma membrane of cells in lipid domains affects the way the membrane interacts with the underlying protein skeleton, which in turn affects the lateral mobility of lipid and protein molecules in the membrane. Membrane fluidit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f2d97d879bd7fbdcd73fbd749612f8
https://pubmed.ncbi.nlm.nih.gov/16603502
https://pubmed.ncbi.nlm.nih.gov/16603502
Autor:
William E, Brownell
Publikováno v:
Acoustics today. 13(1)
Experiments on an inner ear sensory cell revealed that it converts electrical energy directly into mechanical energy at acoustic frequencies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91c89a8ea0423a03f014ceca40c44b0d
https://pubmed.ncbi.nlm.nih.gov/29051713
https://pubmed.ncbi.nlm.nih.gov/29051713
Publikováno v:
Biophysical Journal. 114:671a-672a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49df4b8fd734c406934b364c75ebfe8e
https://doi.org/10.1016/j.bpj.2017.11.3621
https://doi.org/10.1016/j.bpj.2017.11.3621