Zobrazeno 1 - 10
of 53
pro vyhledávání: '"William A. Bridger"'
Autor:
William A. Bridger, Leslie D. Hicks, William T. Wolodko, Edward R. Brownie, Michael N.G. James, Kim Oikawa, Cyril M. Kay, Jean-Christophe Rochet, Marie E. Fraser
Publikováno v:
Biochemistry. 39:11291-11302
Pig heart CoA transferase (EC 2.8.3.5) has been shown previously to adopt a homodimeric structure, in which each subunit has a molecular weight of 52 197 and consists of N- and C-domains linked by a hydrophilic linker or "hinge". Here we identify and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70fc69bb3e014be7cace5c3c275dcee
https://doi.org/10.1021/bi0003184
https://doi.org/10.1021/bi0003184
Publikováno v:
Journal of Molecular Biology. 285:1633-1653
Succinyl-CoA synthetase (SCS) carries out the substrate-level phosphorylation of GDP or ADP in the citric acid cycle. A molecular model of the enzyme from Escherichia coli, crystallized in the presence of CoA, has been refined against data collected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e389cbc287f4e4bae932d5cf4cd9e9fd
https://doi.org/10.1006/jmbi.1998.2324
https://doi.org/10.1006/jmbi.1998.2324
Autor:
Marie E. Fraser, Michael N.G. James, William A. Bridger, Darrin L. Bailey, William T. Wolodko
Publikováno v:
Journal of Molecular Biology. 285:1655-1666
Succinyl-CoA synthetase (SCS) catalyzes the substrate-level phosphorylation step of the citric acid cycle. The enzyme from Escherichia coli is an (αβ)2-heterotetramer with two active sites, one in each αβ-dimer. To determine whether the two activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15c67299adfd1465e2c3484d910647a2
https://doi.org/10.1006/jmbi.1998.2325
https://doi.org/10.1006/jmbi.1998.2325
Publikováno v:
Journal of Biological Chemistry. 272:21151-21159
We have identified two distinct cDNAs encoding the alpha-subunit of pig heart succinyl-CoA synthetase. The derived amino acid sequence of one of these, PHalpha57, is highly similar to the alpha-subunit of the rat liver precursor enzyme. The second cD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83f59a34e5e1f18df448f6a65d5a722
https://doi.org/10.1074/jbc.272.34.21151
https://doi.org/10.1074/jbc.272.34.21151
Autor:
Kim Oikawa, Jean-Christophe Rochet, Leslie D. Hicks, Cyril M. Kay, William T. Wolodko, William A. Bridger
Publikováno v:
Biochemistry. 36:8807-8820
The enzyme CoA transferase from porcine heart (EC 2.8.3.5) is a homodimer; each subunit consists of two domains linked by a hydrophilic "hinge" region. We have prepared separate DNA segments encoding each of these domains. Incorporation of these two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2401128398ccfc43fd9bad2e51da96
https://doi.org/10.1021/bi9703002
https://doi.org/10.1021/bi9703002
Publikováno v:
The Breast Journal. 3:142-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7538bf6f8997bf50466add7687d998f
https://doi.org/10.1111/j.1524-4741.1997.tb00158.x
https://doi.org/10.1111/j.1524-4741.1997.tb00158.x
Publikováno v:
Protein Science. 3:975-981
The enzyme CoA transferase (succinyl-CoA:3-ketoacid coenzyme A transferase [3-oxoacid CoA transferase], EC 2.8.3.5) is essential for the metabolism of ketone bodies in the mammalian mitochondrion. It is known that its catalytic mechanism involves the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::127348888d43923605a0a0a4ef484066
https://doi.org/10.1002/pro.5560030613
https://doi.org/10.1002/pro.5560030613
Publikováno v:
Protein Science. 2:1255-1262
The form of succinyl-CoA synthetase found in mammalian mitochondria is known to be an alpha beta dimer. Both GTP- and ATP-specific isozymes are present in various tissues. We have isolated essentially identical complementary DNA clones encoding the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f6ee5d850fd298d84aefcfeff80dc7
https://doi.org/10.1002/pro.5560020808
https://doi.org/10.1002/pro.5560020808
Autor:
Guohua Fong, William A. Bridger
Publikováno v:
Biochemistry. 31:5661-5664
Succinyl-CoA synthetase of Escherichia coli (alpha 2B2 subunit structure) has been shown to fold and assemble without participation by molecular chaperones. Renaturation experiments showed that purified bacterial chaperone GroEL has no effect on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2385556bcc330e7300bf45b6279747b9
https://doi.org/10.1021/bi00139a033
https://doi.org/10.1021/bi00139a033
Autor:
William A. Bridger, Tianwei Lin
Publikováno v:
Journal of Biological Chemistry. 267:975-978
We have isolated a full-length cDNA clone encoding the cytoplasmic precursor to pig heart mitochondrial CoA transferase (succinyl-CoA:3-ketoacid coenzyme A transferase (3-oxoacid CoA transferase, EC 2.8.3.5], a key enzyme for ketone body catabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2083d8dfca5a5deb7599185922f517a
https://doi.org/10.1016/s0021-9258(18)48381-0
https://doi.org/10.1016/s0021-9258(18)48381-0