Zobrazeno 1 - 10
of 432
pro vyhledávání: '"William A. Bauman"'
Autor:
Carlos A. Toro, Rita De Gasperi, Katherine Vanselow, Lauren Harlow, Kaitlin Johnson, Abdurrahman Aslan, William A. Bauman, Christopher P. Cardozo, Zachary A. Graham
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Traumatic spinal cord injury (SCI) results in the disruption of physiological systems below the level of the spinal lesion. Connexin hemichannels (CxHCs) are membrane-bound, non-selective pore proteins that are lost in mature myofibers but reappear d
Externí odkaz:
https://doaj.org/article/91e5e650b69b49fd9ba9378f869e5e6f
Autor:
Yuanzhen Peng, Helen M. Bramlett, W. Dalton Dietrich, Alex Marcillo, Juliana Sanchez-Molano, Ofelia Furones-Alonso, Jay J. Cao, Jenney Huang, Andrew A. Li, Jian Q. Feng, William A. Bauman, Weiping Qin
Publikováno v:
Bone Reports, Vol 23, Iss , Pp 101808- (2024)
We previously reported an ability of low-intensity vibration (LIV) to improve selected biomarkers of bone turnover and gene expression and reduce osteoclastogenesis but lacking of evident bone accrual. In this study, we demonstrate that a prolonged c
Externí odkaz:
https://doaj.org/article/d83b87086c9640078c1c19b0393202c4
Autor:
Yuanzhen Peng, Solomon Langermann, Priyanka Kothari, Linda Liu, Wei Zhao, Yizhong Hu, Zihao Chen, Mariana Moraes de Lima Perini, Jiliang Li, Jay Cao, X. Edward Guo, Lieping Chen, William A. Bauman, Weiping Qin
Publikováno v:
JBMR Plus, Vol 7, Iss 12, Pp n/a-n/a (2023)
ABSTRACT Rapid and extensive sublesional bone loss after spinal cord injury (SCI) is a difficult medical problem that has been refractory to available interventions except the antiresorptive agent denosumab (DMAB). While DMAB has shown some efficacy
Externí odkaz:
https://doaj.org/article/6c5438c0c2fa41ba8b85c1bb24c33ffb
Autor:
Rita De Gasperi, Chenglin Mo, Daniella Azulai, Zhiying Wang, Lauren M. Harlow, Yating Du, Zachary Graham, Jiangping Pan, Xin‐hua Liu, Lei Guo, Bin Zhang, Fred Ko, Ashleigh M. Raczkowski, William A. Bauman, Chris N. Goulbourne, Wei Zhao, Marco Brotto, Christopher P. Cardozo
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 454-466 (2022)
Abstract Background The role of Numb, a protein that is important for cell fate and development and that, in human muscle, is expressed at reduced levels with advanced age, was investigated; adult mice skeletal muscle and its localization and functio
Externí odkaz:
https://doaj.org/article/e3de719d0af0427d8b54e419b4474d11
Autor:
Yuanzhen Peng, Wei Zhao, Yizhong Hu, X. Edward Guo, Jun Wang, Ke Hao, Zhiming He, Carlos Toro, William A. Bauman, Weiping Qin
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 592-602 (2021)
The administration of high-dose methylprednisolone (MP) for 24?48?h after traumatic spinal cord injury (SCI) has been shown to improve functional recovery. The known adverse effects of MP on skeletal muscle and the immune system, though, have raised
Externí odkaz:
https://doaj.org/article/171dbbee28cd46cd89b59ed2e141ae26
Autor:
Zachary A. Graham, Xin-hua Liu, Lauren Harlow, Jiangping Pan, Daniella Azulai, Hesham A. Tawfeek, Russell D. Wnek, Alex J. Mattingly, William A. Bauman, Joshua F. Yarrow, Christopher P. Cardozo
Publikováno v:
Neurotrauma Reports, Vol 1, Iss 1, Pp 17-31 (2020)
Spinal cord injury (SCI) is associated with obesity and is a risk factor for type 2 diabetes mellitus (T2DM). Immobilization, muscle atrophy, obesity, and loss of sympathetic innervation to the liver are believed to contribute to risks of these abnor
Externí odkaz:
https://doaj.org/article/994cd3d0413242809a7a25ee08c61800
Autor:
Xin-Hua Liu, Zachary A. Graham, Lauren Harlow, Jiangping Pan, Daniella Azulai, William A. Bauman, Joshua Yarrow, Christopher P. Cardozo
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Spinal cord injury (SCI) results in dysregulation of carbohydrate and lipid metabolism; the underlying cellular and physiological mechanisms remain unclear. Fibroblast growth factor 21 (FGF21) is a circulating protein primarily secreted by the liver
Externí odkaz:
https://doaj.org/article/8801932ce00d4b0abb6cbad015707bb6
Autor:
Zachary A. Graham, Abigail Goldberger, Daniella Azulai, Christine F. Conover, Fan Ye, William A. Bauman, Christopher P. Cardozo, Joshua F. Yarrow
Publikováno v:
Physiological Reports, Vol 8, Iss 3, Pp n/a-n/a (2020)
Abstract To determine whether muscle disuse after a spinal cord injury (SCI) produces elevated markers of cellular senescence and induces markers of the senescence‐associated secretory phenotypes (SASPs) in paralyzed skeletal muscle. Four‐month
Externí odkaz:
https://doaj.org/article/3381b354e5b547e59c494fb0e86d9729
Autor:
Jesse A. Lieberman, Jacquelyn W. McClelland, David C. Goff, Elizabeth Racine, Michael F. Dulin, William A. Bauman, Janet Niemeier, Mark A. Hirsch, H. James Norton, Charity G. Moore
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background Individuals with chronic spinal cord injuries (SCIs) have an increased prevalence of cardiovascular disease (CVD) and associated risk factors compared with age-matched control subjects. Exercise has been shown to improve selected
Externí odkaz:
https://doaj.org/article/ba93ef5b4e474f449507f2354dd47851
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 273-280 (2017)
Myostatin is small glycopeptide that is produced and secreted by skeletal muscle. It is a potent negative regulator of muscle growth that has been associated with conditions of frailty. In C2C12 cells, myostatin limits cell differentiation. Myostatin
Externí odkaz:
https://doaj.org/article/336483b5654d4edba26df93cf8964509