Zobrazeno 1 - 10
of 34
pro vyhledávání: '"William A. Alaynick"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
The spinal cord of vertebrate animals is comprised of intrinsic circuits that are capable of sensing the environment and generating complex motor behaviors. There are two major perspectives for understanding the biology of this complicated structure.
Externí odkaz:
https://doaj.org/article/95623797f5c74ef0ac4f5b26ad7b4cc6
Autor:
William A. Alaynick, Massimiliano de Zambotti, Negin Sattari, Fiona C. Baker, Sara C. Mednick, Aimee Goldstone
Publikováno v:
Neurobiology of Learning and Memory. 160:118-131
Age and sex are two of the three major risk factors for Alzheimer’s disease (ApoE-e4 allele is the third), with women having a twofold greater risk for Alzheimer’s disease after the age of 75 years. Sex differences have been shown across a wide r
Publikováno v:
Proceedings of the National Academy of Sciences of USA, vol 118, iss 51
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significant Sleep facilitates both long-term episodic memory consolidation and short-term working memory functioning. However, the mechanism by which the sleeping brain performs both complex feats and which sleep features are associated with these pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e397540666d2298a417bdc3bfcf75ef
https://doi.org/10.1101/2021.03.31.437952
https://doi.org/10.1101/2021.03.31.437952
Autor:
Brooke Curtis, Kefeng Li, Jane C. Naviaux, A. Taylor Bright, Marissa Westerfield, Cynthia Adams, Edmund V. Capparelli, Feng He, Jeanne Townsend, Sonia Jain, Suzanne Goh, Lisa E. Mash, Leanne Chukoskie, Robert K. Naviaux, Lin Wang, Alan J. Lincoln, William A. Alaynick, Ji Sun, Deyna A. Arellano, Gail E. Reiner
Publikováno v:
Annals of Clinical and Translational Neurology
Objective No drug is yet approved to treat the core symptoms of autism spectrum disorder (ASD). Low-dose suramin was effective in the maternal immune activation and Fragile X mouse models of ASD. The Suramin Autism Treatment-1 (SAT-1) trial was a dou
Autor:
Hui Zhong, Takuma Sonoda, V. Reggie Edgerton, Emi Embler, Claire Jang, Roland R. Roy, Gabriel Gomez, Jung A. Kim, Ronald M. Evans, William A. Alaynick
Publikováno v:
Muscle & Nerve. 53:287-296
Introduction Skeletal muscle oxidative capacity decreases and fatigability increases after spinal cord injury. Transcription factor peroxisome proliferator-activated receptor δ (PPARδ) promotes a more oxidative phenotype. Methods We asked whether P
Autor:
Shawn P. Driscoll, William A. Alaynick, Marito Hayashi, Samuel L. Pfaff, Benjamin W. Gallarda, Christopher A. Hinckley, Kathryn L. Hilde, Tatyana O. Sharpee, Joseph D. Dekker, Haley O. Tucker
Publikováno v:
Neuron. 87:1008-1021
SummaryThe coordination of multi-muscle movements originates in the circuitry that regulates the firing patterns of spinal motorneurons. Sensory neurons rely on the musculotopic organization of motorneurons to establish orderly connections, prompting
Publikováno v:
Current Physical Medicine and Rehabilitation Reports. 3:206-213
The spinal cord is often underappreciated as part of the central nervous system. Like the brain, the spinal cord can independently carry out relatively complex behaviors, such as left–right and flexor–extension alternation of the limbs, through a
Autor:
Jae Myoung Suh, Ruth T. Yu, Ronald M. Evans, Jane C. Naviaux, Annette R. Atkins, Christopher Liddle, Andrew Taylor Bright, Robert K. Naviaux, Michael Downes, Kefeng Li, Brett Collins, Christopher E. Wall, William A. Alaynick, Weiwei Fan, Jamie Whyte
Publikováno v:
Proceedings of the National Academy of Sciences. 112:8714-8719
Mitochondria are highly adaptable organelles that can facilitate communication between tissues to meet the energetic demands of the organism. However, the mechanisms by which mitochondria can nonautonomously relay stress signals remain poorly underst
Autor:
Wayne F. Anderson, Jane C. Naviaux, Eric M Gordon, Robert K. Naviaux, A. Taylor Bright, Neil Nathan, Kefeng Li, William A. Alaynick, Lin Wang, Asha Baxter
We thank Vogt et al. for their comments (1). We respond to their three points in order. First, we are aware of the need to extend future metabolomics studies to include other disease groups. We stated this fact in the discussion of ref. 2 and are val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e00e29743465dc704f5d13a5150100
https://europepmc.org/articles/PMC5135342/
https://europepmc.org/articles/PMC5135342/
Autor:
Jane C. Naviaux, Robert K. Naviaux, Kefeng Li, A. Taylor Bright, William A. Alaynick, Wayne F. Anderson, Asha Baxter, Eric M Gordon, Neil Nathan, Lin Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 37
More than 2 million people in the United States have myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We performed targeted, broad-spectrum metabolomics to gain insights into the biology of CFS. We studied a total of 84 subjects using the