Zobrazeno 1 - 10
of 2 307
pro vyhledávání: '"William A Scott"'
Autor:
William A Scott, Erum Z Dhanji, Boris J A Dyakov, Ema S Dreseris, Jonathon S Asa, Laura J Grange, Mila Mirceta, Christopher E Pearson, Grant S Stewart, Anne-Claude Gingras, Eric I Campos
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009909 (2021)
The ATRX ATP-dependent chromatin remodelling/helicase protein associates with the DAXX histone chaperone to deposit histone H3.3 over repetitive DNA regions. Because ATRX-protein interactions impart functions, such as histone deposition, we used prox
Externí odkaz:
https://doaj.org/article/af68af506bd142f7b6d8a3e341ef58e4
Autor:
Chengyu Zhang, Benjamín J Sánchez, Feiran Li, Cheng Wei Quan Eiden, William T Scott, Ulf W Liebal, Lars M Blank, Hendrik G Mengers, Mihail Anton, Albert Tafur Rangel, Sebastián N Mendoza, Lixin Zhang, Jens Nielsen, Hongzhong Lu, Eduard J Kerkhoven
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 10, Pp 1134-1150 (2024)
Abstract Genome-scale metabolic models (GEMs) can facilitate metabolism-focused multi-omics integrative analysis. Since Yeast8, the yeast-GEM of Saccharomyces cerevisiae, published in 2019, has been continuously updated by the community. This has inc
Externí odkaz:
https://doaj.org/article/6ceac2e6fd9f4f218e5ca5c7ed65211e
Autor:
Libor Pastika, Arunashis Sau, Konstantinos Patlatzoglou, Ewa Sieliwonczyk, Antônio H. Ribeiro, Kathryn A. McGurk, Sadia Khan, Danilo Mandic, William R. Scott, James S. Ware, Nicholas S. Peters, Antonio Luiz P. Ribeiro, Daniel B. Kramer, Jonathan W. Waks, Fu Siong Ng
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The electrocardiogram (ECG) can capture obesity-related cardiac changes. Artificial intelligence-enhanced ECG (AI-ECG) can identify subclinical disease. We trained an AI-ECG model to predict body mass index (BMI) from the ECG alone. Develope
Externí odkaz:
https://doaj.org/article/9f47d99e612f4498bb4017febf439586
Autor:
Ekaterine Berishvili, Lorenzo Piemonti, Eelco J. P. de Koning, Sandra Lindstedt, Hanne Scholz, William E. Scott, Celine Auxenfans, Paul Johnson, Dominique E. Martin, Penilla Gunther, Devi Mey, Luciano Potena, Olivier Thaunat
Publikováno v:
Transplant International, Vol 37 (2024)
The field of organ transplantation is experiencing a transformative shift with the rise of Advanced Therapy Medicinal Products (ATMPs), which include gene therapies, somatic cell therapies, and tissue-engineered products. These therapies offer new, p
Externí odkaz:
https://doaj.org/article/3197a6c4257d4e74a3e8072cf5a2021f
Following the tug of the audience from complex to simplified hazards maps at Cascade Range volcanoes
Autor:
Carolyn L. Driedger, David W. Ramsey, William E. Scott, Lisa M. Faust, Joseph A. Bard, Patti Wold
Publikováno v:
Journal of Applied Volcanology, Vol 13, Iss 1, Pp 1-18 (2024)
Abstract Volcano-hazard maps are broadly recognized as important tools for forecasting and managing volcanic crises and for disseminating spatial information to authorities and people at risk. As scientists, we might presume that hazards maps can be
Externí odkaz:
https://doaj.org/article/6f39560cf5044926887c155505ae2091
Autor:
Efstathios S. Avgoustiniatos, Kate R. Mueller, William E. Scott III, Jennifer P. Kitzmann, Thomas M. Suszynski, Brian E. Perrault, Eric J. Falde, A. N. Balamurugan, Bernhard J. Hering, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
IntroductionConventional culture conditions, such as in T-flasks, require that oxygen diffuse through the medium to reach the islets; in turn, islet surface area density is limited by oxygen availability. To culture a typical clinical islet preparati
Externí odkaz:
https://doaj.org/article/6e961f6e73b748fc88ec72a36aad0d63
Autor:
Katharina F. Heil, Anze Zupanic, Chris T. Evelo, Carole Goble, Kristel Van Steen, Tadeja Rezen, Hans V Westerhoff, Rahuman S. Malik Sheriff, Maria Suarez Diez, Henning Hermjakob, Marco Pagni, Damjana Rozman, Barbara Szomolay, Miguel Rocha, Jasper Koehorst, Alexey Kolodkin, Victoria Dominguez Del Angel, David Šafránek, Dirk Fey, Ilja Arts, Rui Benfeitas, Vitor Martins dos Santos, Mihail Anton, Marek Ostaszewski, Ulrike Wittig, John M. Hancock, Brane Leskošek, Katherine Wolstencroft, Martin Golebiewski, Wolfgang Müller, Polonca Ferk, Kristina Gruden, William T. Scott, Elena Domínguez-Romero, Martina Kutmon, Maria I. Klapa, Sébastien Moretti, Pascal Kahlem
Publikováno v:
F1000Research, Vol 11 (2024)
In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community beli
Externí odkaz:
https://doaj.org/article/231bbdc173f041d7b339528a06d2b5e4
Autor:
Julian D. Dallmeier, Ryan Gober, Regina T. Vontell, Ayled Barreda, Daniel A. Dorfsman, David A. Davis, Xiaoyan Sun, Daniel Brzostowicki, Illiana Bennett, Susanna P. Garamszegi, Connor M. Wander, Todd Cohen, William K. Scott
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionSeverity and distribution of aggregated tau and neurofibrillary tangles (NFT) are strongly correlated with the clinical presentation of Alzheimer’s disease (AD). Clearance of aggregated tau could decrease the rate of NFT formation and d
Externí odkaz:
https://doaj.org/article/d606ce4d937341f9881e87e417b730aa
Autor:
Madeline Alizadeh, Uni Wong, Bernadette C. Siaton, Seema A. Patil, Lauren George, Jean-Pierre Raufman, William H. Scott, Erik C. von Rosenvinge, Jacques Ravel, Raymond K. Cross
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26571- (2024)
Background: Inflammatory Bowel Disease (IBD)-associated arthritis is a frequent and potentially debilitating complication of IBD, that can affect those with or without active intestinal disease, and is often difficult to treat. The microbiome is know
Externí odkaz:
https://doaj.org/article/326a44670ac74751b5faba920544b242
Autor:
Liam McAllan, Damir Baranasic, Sergio Villicaña, Scarlett Brown, Weihua Zhang, Benjamin Lehne, Marco Adamo, Andrew Jenkinson, Mohamed Elkalaawy, Borzoueh Mohammadi, Majid Hashemi, Nadia Fernandes, Nathalie Lambie, Richard Williams, Colette Christiansen, Youwen Yang, Liudmila Zudina, Vasiliki Lagou, Sili Tan, Juan Castillo-Fernandez, James W. D. King, Richie Soong, Paul Elliott, James Scott, Inga Prokopenko, Inês Cebola, Marie Loh, Boris Lenhard, Rachel L. Batterham, Jordana T. Bell, John C. Chambers, Jaspal S. Kooner, William R. Scott
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract DNA methylation variations are prevalent in human obesity but evidence of a causative role in disease pathogenesis is limited. Here, we combine epigenome-wide association and integrative genomics to investigate the impact of adipocyte DNA me
Externí odkaz:
https://doaj.org/article/ea82019d0abe4ca49fb6dbbbe87cd979