Zobrazeno 1 - 10
of 1 903
pro vyhledávání: '"William A, Wood"'
Autor:
William A. Wood, Carly Bailey, Brianna Castrogivanni, Diana Mehedint, Ashley Leak Bryant, Kyle Lavin, Xianming Tan, Jaime Richardson, Yiqing Qian, Kelly R. Tan, Erin E. Kent
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8804-8814 (2023)
Abstract Background Cancer supportive care interventions often have limited generalizability, goal misalignment, and high costs. We developed and piloted a health coaching intervention, UNC HealthScore, in patients undergoing cancer treatment (Clinic
Externí odkaz:
https://doaj.org/article/935630da927f40fe8e23cbfd9a8d079d
Autor:
Marina Weiler, Kevin C. Stieger, Kavisha Shroff, Jessie P. Klein, William H. Wood, Yongqing Zhang, Prabha Chandrasekaran, Elin Lehrmann, Simonetta Camandola, Jeffrey M. Long, Mark P. Mattson, Kevin G. Becker, Peter R. Rapp
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
IntroductionTranscranial Magnetic Stimulation (TMS) is a noninvasive technique that uses pulsed magnetic fields to affect the physiology of the brain and central nervous system. Repetitive TMS (rTMS) has been used to study and treat several neurologi
Externí odkaz:
https://doaj.org/article/34f79dae29cb47b98cb8b8caed4990f0
Autor:
Barbara Savoldo, Gianpietro Dotti, Allison M Deal, Jonathan S Serody, Christopher Dittus, Nicholas P Tschernia, Hillary Heiling, Catherine Cheng, Caroline Babinec, Megan Gonzalez, J Kaitlin Morrison, Anne W Beaven, William A Wood, Natalie S Grover
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Chimeric antigen receptor (CAR)-T cells targeting CD30 have demonstrated high response rates with durable remissions observed in a subset of patients with relapsed/refractory CD30+ hematologic malignancies, particularly classical Hodgkin lymphoma. Th
Externí odkaz:
https://doaj.org/article/37ff0a870b1541c7ae281d7f0e1e2333
Autor:
Benyam Muluneh, Michele A Muir, James Bernard Collins, Darrian Proco, Emily Mackler, Ashley Leak Bryant, William A Wood, Michael Tilkens, Jeffrey S Reichard, Matthew Foster, Justin Gatwood, Stephanie B Wheeler, Leah L Zullig, Jennifer Elston Lafata
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0286630 (2023)
PurposeThe goal of this study is to determine barriers and facilitators to the implementation of medication adherence interventions to support cancer patients taking novel, targeted oral anticancer agents (OAAs).MethodsWe conducted qualitative interv
Externí odkaz:
https://doaj.org/article/fd29ebf62052481291363b91f3edfc74
Autor:
Smit Patel, Jennifer C Goldsack, Grace Cordovano, Andrea Downing, Karen K Fields, Cindy Geoghegan, Upinder Grewal, Jorge Nieva, Nikunj Patel, Dana E Rollison, Archana Sah, Maya Said, Isabel Van De Keere, Amanda Way, Dana L Wolff-Hughes, William A Wood, Edmondo J Robinson
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e43404 (2023)
Although health care delivery is becoming increasingly digitized, driven by the pursuit of improved access, equity, efficiency, and effectiveness, progress does not appear to be equally distributed across therapeutic areas. Oncology is renowned for l
Externí odkaz:
https://doaj.org/article/6e56181c278f47708e805209d9b5bb9e
Autor:
William A Wood, Deepika Dilip, Andriy Derkach, Natalie S Grover, Olivier Elemento, Ross Levine, Gita Thanarajasingam, John A Batsis, Charlotte Bailey, Arun Kannappan, Steven M Devine, Andrew S Artz, Jennifer A Ligibel, Ethan Basch, Erin Kent, Jacob Glass
Publikováno v:
PLOS Digital Health, Vol 2, Iss 1, p e0000178 (2023)
Clinical performance status is designed to be a measure of overall health, reflecting a patient's physiological reserve and ability to tolerate various forms of therapy. Currently, it is measured by a combination of subjective clinician assessment an
Externí odkaz:
https://doaj.org/article/e0deabaf558f4a148b9ed629f56db538
Autor:
Amanda J Stock, Ross A McDevitt, Chandrakala Puligilla, Yajun Wang, Yongqing Zhang, Kun Wang, Chongkui Sun, Kevin G Becker, Elin Lehrmann, William H Wood, Yi Gong, Mohammad Aqdas, Myong-Hee Sung, Victoria Hoffmann, Chengyu Liu, Myriam Gorospe, Lea Harrington, Luigi Ferrucci, Yie Liu
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010506 (2022)
Short telomeres induce a DNA damage response (DDR) that evokes apoptosis and senescence in human cells. An extant question is the contribution of telomere dysfunction-induced DDR to the phenotypes observed in aging and telomere biology disorders. One
Externí odkaz:
https://doaj.org/article/42f878754db94ac392eb2d05bf6182d1
Autor:
Elena S. Izmailova, William A. Wood, Qi Liu, Vadim Zipunnikov, Daniel Bloomfield, Jason Homsy, Steven C. Hoffmann, John A. Wagner, Joseph P. Menetski
Publikováno v:
Digital Biomarkers, Vol 5, Iss 1, Pp 103-113 (2021)
Clinical safety findings remain one of the reasons for attrition of drug candidates during clinical development. Cardiovascular liabilities are not consistently detected in early-stage clinical trials and often become apparent when drugs are administ
Externí odkaz:
https://doaj.org/article/be50585e4af844f08bb9c2e2dbbc3169
Autor:
Robert A. Tumasian, Abhinav Harish, Gautam Kundu, Jen-Hao Yang, Ceereena Ubaida-Mohien, Marta Gonzalez-Freire, Mary Kaileh, Linda M. Zukley, Chee W. Chia, Alexey Lyashkov, William H. Wood, Yulan Piao, Christopher Coletta, Jun Ding, Myriam Gorospe, Ranjan Sen, Supriyo De, Luigi Ferrucci
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
As human skeletal muscle ages, gene expression programs change and reflect damage accumulation and homeostatic resilience mechanisms. Here, the authors present a detailed framework of the global transcriptome that characterizes skeletal muscle during
Externí odkaz:
https://doaj.org/article/fe1b133469394d2ea2f9de8c7479f7a6
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Oligodendrocyte precursor cell (OPC) proliferation and differentiation is greater in white matter than gray matter. Here, the authors show regulation of OPC proliferation in white matter involved trans-activation of PDGFRα on OPCs via Nrp1 expressed
Externí odkaz:
https://doaj.org/article/3fe090a54fae4abb94913b0060155aa9