Zobrazeno 1 - 10
of 58
pro vyhledávání: '"William L. Mitchell"'
Autor:
William L. Mitchell, Dante Abate, Kevin S. Colls, Marina Faka, Caroline Sturdy Colls, Nikolas Bakirtzis
Publikováno v:
Heritage, Vol 5, Iss 1, Pp 260-285 (2022)
In the framework of the IH-AT (Invisible Heritage Analysis and Technology) project, a cluster of churches ranging from the 11th to the 16th centuries, located in the Troodos Mountain range of Cyprus, designated by UNESCO as World Heritage monuments,
Externí odkaz:
https://doaj.org/article/77f3b9ac44ce4ae0a8d98eab09a2745e
Autor:
Vimal Dhokia, Matthew Young, James L. J. Bilzon, William L. Mitchell, Elena Seminati, David Canepa Talamas
Publikováno v:
Procedia CIRP. 60:476-481
The objective of personalization is to create a product that matches the exacting requirements of the individual consumer. Where these products must interface with the changing dynamics of the human form, traditional manufacturing techniques, coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b92ed0800334b97775524e9d6eccf64
https://doi.org/10.1016/j.procir.2017.02.049
https://doi.org/10.1016/j.procir.2017.02.049
Autor:
Robert M. Clark, William L. Mitchell
'The chapters on the exercises are a treasure chest of material to work with, covering a whole array of scenarios.... I think virtually every page and topic could spark robust and spirited classroom discussion starting with the text title itself.'—
Autor:
Robert M. Clark, William L. Mitchell
In Target-Centric Network Modeling: Case Studies in Analyzing Complex Intelligence Issues, authors Robert Clark and William Mitchell take an entirely new approach to teaching intelligence analysis. Unlike any other book on the market, it offers case
Autor:
Gerard Martin Paul Giblin, Paul Goldsmith, Andrew John Eatherton, William L. Mitchell, Brian Peter Slingsby, Andrew Billinton, Alan Naylor, Alex W. Wilson, Andrew J. Brown, Carl Haslam, Matthew R. Johnson, Iain P. Chessell, Alcide Perboni, Michael A. Briggs, Nick M. Clayton
Publikováno v:
Journal of Medicinal Chemistry. 52:5785-5788
We report the synthesis and SAR of a series of novel azaindole CB(2) agonists. 6-Azaindole 18 showed activity in an acute pain model but was inactive in a chronic model. 18 is a Pgp substrate with low brain penetration. The template was redesigned, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d31fdf1a41880ef864d92a59ab1d7e8
https://doi.org/10.1021/jm9009857
https://doi.org/10.1021/jm9009857
Autor:
Celestine T. O'Shaughnessy, Gerard Martin Paul Giblin, Brian Peter Slingsby, Carl Haslam, Alan Naylor, Andrew John Eatherton, Alex W. Wilson, and Andrew R. Wittington, Nick M. Clayton, Richard D. Green, Paul Goldsmith, William L. Mitchell, D. Anthony Rawlings, Andrew J. Brown, Iain P. Chessell
Publikováno v:
Journal of Medicinal Chemistry. 50:2597-2600
Selective CB2 receptor agonists are promising potential therapeutic agents for the treatment of inflammatory and neuropathic pain. A focused screen identified a pyrimidine ester as a partial agonist at the CB2 receptor with micromolar potency. Subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a29c61610207cdd4903eac8b50295f34
https://doi.org/10.1021/jm061195+
https://doi.org/10.1021/jm061195+
Autor:
Leticia Toledo-Sherman, Catherine M. O'Connell, Christopher John Yarnold, Michael Prime, Suganathan Selvaratnam, Ignacio Munoz-Sanjuan, Ladislav Mrzljak, Arash Rassoulpour, Kimberly L Matthews, Patricia Wheelan, Laura Reed, Wolfgang Reindl, Alan Beresford, Estelle Hamelin-Flegg, Derek Alexander Weddell, William L. Mitchell, Dawn Yates, Maria Beconi, Weslyn Ward Friley, Christopher John Brown, Christin Winkler, Stephen Martin Courtney, Valerie Kempf, John Wityak, Naomi Went, Celia Dominguez, Isabell Cardaun, Kendall D. Powell, Ulrike Dijkman, Peter Johnson, Frederick Arthur Brookfield, Dirk Winkler, De Aguiar Pena Paula C, Kathy Lyons
Publikováno v:
Journal of medicinal chemistry. 58(3)
We report on the development of a series of pyrimidine carboxylic acids that are potent and selective inhibitors of kynurenine monooxygenase and competitive for kynurenine. We describe the SAR for this novel series and report on their inhibition of K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699f24106f0a18d2d3d4ac5e1d3ff8ca
https://pubmed.ncbi.nlm.nih.gov/25590515
https://pubmed.ncbi.nlm.nih.gov/25590515
Publikováno v:
Collection of Czechoslovak Chemical Communications. 68:907-916
The title compound 7 has been synthesized in a racemic form, using Suzuki coupling (8 + 15 → 16) as the key step. Pure enantiomer (S)-(-)-7 has been obtained by carbonylation of the known bromide (S)-(+)-12 followed by reduction of the resulting me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d67da3aa2b5254caae87ab1e76141e77
https://doi.org/10.1135/cccc20030907
https://doi.org/10.1135/cccc20030907