Zobrazeno 1 - 10
of 93
pro vyhledávání: '"William, J John"'
Autor:
Jonathan W. Goldman, Julien Mazieres, Fabrice Barlesi, Konstantin H. Dragnev, Marianna Koczywas, Tuncay Göskel, Alexis B. Cortot, Nicolas Girard, Claas Wesseler, Helge Bischoff, Ernest Nadal, Keunchil Park, Shun Lu, Alvaro Taus, Manuel Cobo, Shawn T. Estrem, Sameera R. Wijayawardana, Kellie Turner, Gerard Joseph Oakley, Karla C. Hurt, Alan Y. Chiang, Anwar M. Hossain, William J. John, Luis Paz-Ares
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
IntroductionJUNIPER compared the efficacy and safety of abemaciclib, a selective cyclin-dependent kinase 4 and 6 inhibitor, with erlotinib in patients with non-small cell lung cancer (NSCLC) harboring a Kirsten rat sarcoma (KRAS) mutation.MethodsJUNI
Externí odkaz:
https://doaj.org/article/4c938db73a4443b18e2317f0a0f304fd
Autor:
Rebecca Ellen Goulding, Matthew Chenoweth, Gebra Cuyun Carter, Mark Ernest Boye, Kristin M Sheffield, William J John, Mark Steven Leusch, Catherine Elizabeth Muehlenbein, Li Li, Min-Hua Jen, Adina Rojubally, Jeroen Jansen, Eric Druyts
Publikováno v:
Cancer Treatment and Research Communications, Vol 24, Iss , Pp 100200- (2020)
KRAS (Kirsten Rat Sarcoma) is the most common oncogenic mutation detected in patients with non-small cell lung cancer (NSCLC). However, the role of KRAS as either a prognostic factor or predictive factor (modifier of treatment effects) in NSCLC is no
Externí odkaz:
https://doaj.org/article/8d4a2489397e4e478a6287ecb9ffb2ec
Autor:
Jonathan W. Goldman, William J. John, Anwar Hossain, Richard Beckmann, Siva Rama Prasad Kambhampati, P. Kellie Turner, Erica L. Johnston, Monte Shaheen, Eric Schaefer, Mariano Provencio, Martin Gutierrez, Daruka Mahadevan, Shadia Jalal, Pilar Garrido, Luis G. Paz-Ares, Karen Kelly, Edward S. Kim
First part of the appendix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cd31f5d7f6762afe34223c2a1cdecd
https://doi.org/10.1158/1078-0432.22470777
https://doi.org/10.1158/1078-0432.22470777
Autor:
Jonathan W. Goldman, William J. John, Anwar Hossain, Richard Beckmann, Siva Rama Prasad Kambhampati, P. Kellie Turner, Erica L. Johnston, Monte Shaheen, Eric Schaefer, Mariano Provencio, Martin Gutierrez, Daruka Mahadevan, Shadia Jalal, Pilar Garrido, Luis G. Paz-Ares, Karen Kelly, Edward S. Kim
Third part of the appendix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242623715c2e35989bbd2a74c402090e
https://doi.org/10.1158/1078-0432.22470783.v1
https://doi.org/10.1158/1078-0432.22470783.v1
Autor:
Jonathan W. Goldman, William J. John, Anwar Hossain, Richard Beckmann, Siva Rama Prasad Kambhampati, P. Kellie Turner, Erica L. Johnston, Monte Shaheen, Eric Schaefer, Mariano Provencio, Martin Gutierrez, Daruka Mahadevan, Shadia Jalal, Pilar Garrido, Luis G. Paz-Ares, Karen Kelly, Edward S. Kim
Purpose: Abemaciclib, a dual inhibitor of cyclin-dependent kinases 4 and 6, has demonstrated preclinical activity in non–small cell lung cancer (NSCLC). A multicenter, nonrandomized, open-label phase Ib study was conducted to test safety, MTD, phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247771de316daddf898dbc0b82a5449e
https://doi.org/10.1158/1078-0432.c.6527679
https://doi.org/10.1158/1078-0432.c.6527679
Autor:
Luis Paz-Ares, Irene Ferrer, Gerald Schmid-Bindert, Stephan Herbertz, William J. John, Jon Zugazagoitia
Publikováno v:
Lung Cancer. 124:53-64
In patients with non-small cell lung cancer (NSCLC), the most frequent oncogene driver mutation in Western countries is Kirsten rat sarcoma viral oncogene homolog (KRAS), and KRAS-mutant NSCLC is associated with smoking. There are various sources of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d43ad1245d30ff4ef6d4a15227331b1
https://doi.org/10.1016/j.lungcan.2018.07.013
https://doi.org/10.1016/j.lungcan.2018.07.013
Publikováno v:
Clinical Lung Cancer. 18:607-614
Brain metastases (BRM) occur frequently in non-small-cell lung cancer (NSCLC) and present a substantial unmet medical need. Previous literature on global BRM prevalence, treatment patterns, costs, and outcomes typically has described a subset of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dde5059624b83d4c83093a0d0a0d763
https://doi.org/10.1016/j.cllc.2017.04.011
https://doi.org/10.1016/j.cllc.2017.04.011
Publikováno v:
Current Medical Research and Opinion. 33:931-936
Pemetrexed plus carboplatin (PCb) is a frequently used first-line treatment in advanced non-small cell lung cancer (NSCLC). This study examined the characteristics and safety profile of a NSCLC population treated with PCb area under the concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86090a0de350acd53e3266f44d7a659
https://doi.org/10.1080/03007995.2017.1297700
https://doi.org/10.1080/03007995.2017.1297700
Autor:
William J. John, Tudor Ciuleanu, Luis Paz-Ares, Belen San Antonio, Jonathan Denne, Nancy Iturria, Giorgio V. Scagliotti, Annamaria Zimmermann, Paul A. Bunn
Publikováno v:
Lung Cancer. 104:45-51
In clinical practice, elderly patients are often undertreated relative to younger patients. This meta-analysis was designed to determine whether older patients with non-squamous non-small cell lung cancer (NSCLC) could derive an overall survival (OS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2419470db992bb706e7def5566025eb2
https://doi.org/10.1016/j.lungcan.2016.12.007
https://doi.org/10.1016/j.lungcan.2016.12.007
Publikováno v:
Journal of thoracic disease. 11(11)
Background: We analyzed the treatment patterns and safety outcomes of the most common first-line platinum-based regimens initiated on or after non-small cell lung cancer (NSCLC) diagnosis in a real-world setting. Methods: Based on a United States onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19c9e6f10d025dafaadedba1591c3d7
https://pubmed.ncbi.nlm.nih.gov/31903235
https://pubmed.ncbi.nlm.nih.gov/31903235