Výsledky vyhledávání

Akademický článek

Two-year change in cognitive function is associated with changes in vascular function in a diverse cohort of middle-aged adults at-risk for Alzheimer's disease

Autor: Brittany Butts, William Hu, Arshed Quyyumi, Monica Parker, Sonum Tharwani, Harry Huang, Danielle Verble, Whitney Wharton

Publikováno v: Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100275- (2024)

Introduction: The rate of Alzheimer's disease (AD) for Black Americans (BAs) is 64% higher than for non-Hispanic White Americans (NHWs). Vascular dysfunction may directly contribute to pathologies related to AD and cognitive decline. The purpose of t

Externí odkaz: https://doaj.org/article/2c1384904cca465e8a1df6404458d69b

Zobrazit plný text záznamu

Akademický článek

Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27

Autor: Xiuye Wang, Thomas Hennig, Adam W. Whisnant, Florian Erhard, Bhupesh K. Prusty, Caroline C. Friedel, Elmira Forouzmand, William Hu, Luke Erber, Yue Chen, Rozanne M. Sandri-Goldin, Lars Dölken, Yongsheng Shi

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

Herpes simplex virus-1 (HSV-1) infection disrupts transcription termination (DoTT) of host genes, but underlying mechanisms are unclear. Here, Wang et al. show that the HSV-1 immediate early protein ICP27 induces DoTT through interaction with the mRN

Externí odkaz: https://doaj.org/article/86795a19df404ef6a9b5cb941f4f5451

Zobrazit plný text záznamu

Akademický článek

A Pilot randomized clinical trial of adapted tango to improve cognition and psychosocial function in African American women with family history of Alzheimer's disease (ACT trial)

Autor: Whitney Wharton, Leanne Jeong, Liang Ni, Allison A. Bay, Ryan J. Shin, Lauren E. McCullough, Hayley Silverstein, Ariel R. Hart, Dominika Swieboda, William Hu, Madeleine E. Hackney

Publikováno v: Cerebral Circulation - Cognition and Behavior, Vol 2, Iss , Pp 100018- (2021)

Alzheimer's disease (AD) is a devastating, progressive neurodegenerative disease resulting in memory loss and a severe reduction in the ability to perform activities of daily living. Ethnicity-related genetic factors promoting the development of deme

Externí odkaz: https://doaj.org/article/89ec6cac9a244ed9bd6ab27fbf5aa7f6

Zobrazit plný text záznamu

Supplementary Figures S1 to S11 from Tumor Cells Chronically Treated with a Trastuzumab–Maytansinoid Antibody–Drug Conjugate Develop Varied Resistance Mechanisms but Respond to Alternate Treatments

Supplementary Figures S1 to S11. Supplementary Figure S1: Schematic illustration of the approach used to create trastuzumab-maytansinoid ADC resistant cell lines. Supplementary Figure S2: Structures of payloads and ADCs. Supplementary Figure S3: 361-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79603999d612f532f7eea3bb1f02469
https://doi.org/10.1158/1535-7163.22500637.v1

Zobrazit plný text záznamu

Supplementary Methods, Table S1 S2, and Figure Legends from Tumor Cells Chronically Treated with a Trastuzumab–Maytansinoid Antibody–Drug Conjugate Develop Varied Resistance Mechanisms but Respond to Alternate Treatments

Supplementary Methods, Table S1 S2, and Figure Legends. Supplementary Table S1: Properties of cell lines made resistant to TM-conjugate. Supplementary Table S2: Relative resistance of selected free payloads and Cys-capped-released species in H69 (no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030c02d31cd9136288d63c1ed31908a5
https://doi.org/10.1158/1535-7163.22500634.v1

Zobrazit plný text záznamu

Potential Multiple Myeloma Therapeutic Strategies through Targeting Macrophages and Mesenchymal Stromal Cells

Autor: William Hu

Publikováno v: Journal of Student Research. 12

Multiple Myeloma (MM), a bone marrow plasma cell hematopoietic cancer, remains a critical but incurable hematological malignancy, prone to deadly relapses even after existing treatment. In this review, I describe the origins of pro-tumor myeloma-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9230c65573490c07cdbb9b09928532df
https://doi.org/10.47611/jsr.v12i1.1870

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání