Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Willi Dr Diederen"'
Autor:
Annerose Mauz, Joanne van Ryn, Ray Winquist, Michel Pairet, Hans Schierok, Michael P. Pieper, Alexander Walland, Willi Dr Diederen, Brian Guth, Kozo Kanai
Publikováno v:
Drug Development Research. 42:57-62
The objectives of general pharmacology (GP) studies from the point of view of pharmacologists working in the pharmaceutical industry are presented and compared with the requirements of regulatory authorities, using the Japanese Guidelines as an examp
Autor:
Michel Pairet, J. Van Ryn, Willi Dr Diederen, Guenther Dr Engelhardt, Hans Schierok, D. Türck, Annerose Mauz
Publikováno v:
Selective COX-2 Inhibitors ISBN: 9789401060417
Since the discovery of a second isoenzyme of cyclooxygenase (COX), COX-21,2, it has been hypothesized that the anti-inflammatory effects of non-steroid anti-inflammatory drugs (NSAIDs) are achieved through a mechanism different from that underlying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9cf5587109b2a6d1bb96fbb980e9508
https://doi.org/10.1007/978-94-011-4872-6_3
https://doi.org/10.1007/978-94-011-4872-6_3
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 351(6)
Recent data show that UD-CG 212 in nanomolar concentrations increases myofibrillar Ca++ responsiveness of chemically skinned cardiac preparations in the presence of elevated inorganic phosphate. We studied the effects of UD-CG 212 on cell shortening
Autor:
Michel Pairet, Henri Doods, Willi Dr Diederen, Marco Turconi, Wolfgang Wienen, Van Meel Jacques, Robert M. Haigh
Publikováno v:
European journal of pharmacology. 233(2-3)
The 5-HT4 receptor antagonist action of DAU 6285 was investigated in vivo in anesthetized pigs. DAU 6285 (0.3–3 mg/kg i.v.) dose dependently antagonized 5-hydroxytryptamine (5-HT)-induced tachycardiac responses. In contrast, the 5-HT3 receptor anta
Publikováno v:
Journal of Cardiovascular Pharmacology. 13:508
We investigated the effect of the new cardiotonic drug pimobendan on survival of hereditary cardiomyopathic hamsters. Untreated cardiomyopathic hamsters served as controls. A 50% mortality was observed after 280 days for the control group and after 3