Altered whole blood thrombin generation and hyperresponsive platelets in patients with pancreatic cancer.

Autor: Willems RAL; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Thrombosis Expert Center Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Internal Medicine, Division of Vascular Medicine, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Internal Medicine, Division of Medical Oncology, Maastricht University Medical Center, Maastricht, The Netherlands; Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, Maastricht, The Netherlands. Electronic address: ruth.willems@mumc.nl., Konings J; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, The Netherlands., Huskens D; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, The Netherlands., Middelveld H; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, The Netherlands., Pepels-Aarts N; Department of Internal Medicine, Division of Medical Oncology, Maastricht University Medical Center, Maastricht, The Netherlands., Verbeet L; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, The Netherlands., de Groot PG; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, Maastricht, The Netherlands., Heemskerk JWM; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, Maastricht, The Netherlands; Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, The Netherlands., Ten Cate H; Thrombosis Expert Center Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Internal Medicine, Division of Vascular Medicine, Maastricht University Medical Center, Maastricht, The Netherlands; Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, Maastricht, The Netherlands; Center of Thrombosis and Haemostasis, Gutenberg University Medical Center, Mainz, Germany., de Vos-Geelen J; Department of Internal Medicine, Division of Medical Oncology, Maastricht University Medical Center, Maastricht, The Netherlands; GROW, Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, The Netherlands., de Laat B; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, Maastricht, The Netherlands; Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, The Netherlands., Roest M; Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands; Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, The Netherlands.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Apr; Vol. 22 (4), pp. 1132-1144. Date of Electronic Publication: 2024 Jan 17.

Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis.

Autor: Akbulut AC; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Arisz RA; Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Baaten CCFMJ; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Institute for Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Aachen, Germany., Baidildinova G; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Barakzie A; Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Bauersachs R; Cardioangiologisches Centrum Bethanien - CCB, Gefäß-Centrum, Frankfurt am Main, Germany., Ten Berg J; Department of Cardio-Thoracic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., van den Broek WWA; Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands., de Boer HC; Department of Internal Medicine (Nephrology) and the Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands., Bonifay A; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France.; Department of Hematology and Vascular Biology, CHU La TIMONE, APHM, Marseille, France., Bröker V; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Buka RJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, United Kingdom., Ten Cate H; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany.; Thrombosis Expertise Center, Maastricht University Medical Center, Maastricht, The Netherlands., Ten Cate-Hoek AJ; Thrombosis Expertise Center, Maastricht University Medical Center, Maastricht, The Netherlands., Cointe S; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France.; Department of Hematology and Vascular Biology, CHU La TIMONE, APHM, Marseille, France., De Luca C; Laboratory of Morphology of Neuronal Networks and Systems Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania 'Luigi Vanvitelli,' Napoli, Italy., De Simone I; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Diaz RV; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany.; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France., Dignat-George F; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France.; Department of Hematology and Vascular Biology, CHU La TIMONE, APHM, Marseille, France., Freson K; Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium., Gazzaniga G; Department of Cardio-Thoracic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.; Department of Clinical-Surgical, Diagnostic and Pediatric Science, University of Pavia, Pavia, Italy., van Gorp ECM; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands., Habibi A; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Henskens YMC; Central Diagnostic Laboratory, Unit for Hemostasis and Transfusion, Maastricht University Medical Centre + , Maastricht, The Netherlands., Iding AFJ; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Thrombosis Expertise Center, Maastricht University Medical Center, Maastricht, The Netherlands., Khan A; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, United Kingdom.; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine and National Institute of Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom., Koenderink GH; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, The Netherlands., Konkoth A; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France., Lacroix R; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France.; Department of Hematology and Vascular Biology, CHU La TIMONE, APHM, Marseille, France., Lahiri T; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany.; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France., Lam W; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, United States., Lamerton RE; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, United Kingdom., Lorusso R; Department of Cardio-Thoracic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., Luo Q; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Maas C; CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., McCarty OJT; Department of Biomedical Engineering, Oregon Health and Science University, Portland, Oregon, United States., van der Meijden PEJ; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Thrombosis Expertise Center, Maastricht University Medical Center, Maastricht, The Netherlands., Meijers JCM; Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands.; Department of Experimental Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, The Netherlands., Mohapatra AK; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Institute for Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Aachen, Germany.; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France., Nevo N; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.; Department of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Robles AP; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Poncelet P; R and T Department, BioCytex, Marseille, France., Reinhardt C; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Ruf W; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Saraswat R; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany.; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France., Schönichen C; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Schutgens R; Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, UMC Utrecht, University Utrecht, Utrecht, The Netherlands., Simioni P; General Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padua University Hospital and University of Padua Medical School, Padua, Italy., Spada S; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Spronk HMH; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Thrombosis Expertise Center, Maastricht University Medical Center, Maastricht, The Netherlands., Tazhibayeva K; Cancer Center of Shymkent, Al-Farabi Kazakh National University, Almaty, Kazakhstan., Thachil J; Department of Haematology, Manchester University Hospitals, Manchester, United Kingdom., Diaz RV; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany.; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France., Vallier L; Aix-Marseille University, C2VN, INSERM 1263, INRAE 1260, Marseille, France., Veninga A; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Verhamme P; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Visser C; Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Watson SP; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, United Kingdom., Wenzel P; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., Willems RAL; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Willers A; Department of Cardio-Thoracic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., Zhang P; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany.; Leibniz Institute for Analytical Sciences - ISAS-e.V., Dortmund, Germany., Zifkos K; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, Mainz, Germany., van Zonneveld AJ; Department of Internal Medicine (Nephrology) and the Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands.

Publikováno v: Thrombosis and haemostasis [Thromb Haemost] 2023 Aug; Vol. 123 (8), pp. 808-839. Date of Electronic Publication: 2023 Mar 13.

Evolving data on cardiovascular complications in cancer.

Autor: Willems RAL; Thrombosis Expert Center Maastricht and Department of Internal Medicine, Section Vascular Medicine, Maastricht University Medical Center, Maastricht, the Netherlands., Winckers K; Thrombosis Expert Center Maastricht and Department of Internal Medicine, Section Vascular Medicine, Maastricht University Medical Center, Maastricht, the Netherlands; Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, Maastricht, the Netherlands., Biesmans C; Department of Internal Medicine, Section Medical Oncology, Maastricht University Medical Center, Maastricht, the Netherlands., de Vos-Geelen J; Department of Internal Medicine, Section Medical Oncology, Maastricht University Medical Center, Maastricht, the Netherlands; GROW, School for Oncology and Developmental Biology, Maastricht, the Netherlands., Ten Cate H; Thrombosis Expert Center Maastricht and Department of Internal Medicine, Section Vascular Medicine, Maastricht University Medical Center, Maastricht, the Netherlands; Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, Maastricht, the Netherlands. Electronic address: h.tencate@maastrichtuniversity.nl.

Publikováno v: Thrombosis research [Thromb Res] 2022 May; Vol. 213 Suppl 1, pp. S87-S94. Date of Electronic Publication: 2022 May 26.

Co-administration of Anti microRNA-124 and -137 Oligonucleotides Prevents Hippocampal Neural Stem Cell Loss Upon Non-convulsive Seizures.

Autor: Bielefeld P; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Schouten M; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Meijer GM; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Breuk MJ; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Geijtenbeek K; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Karayel S; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Tiaglik A; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Vuuregge AH; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Willems RAL; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Witkamp D; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Lucassen PJ; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands., Encinas JM; Achucarro Basque Center for Neuroscience, Bizkaia Science and Technology Park, Zamudio, Spain.; Ikerbasque Foundation, Bilbao, Spain.; University of the Basque Country (UPV/EHU), Leioa, Spain., Fitzsimons CP; Neuroscience Program, Swammerdam Institute for Life Sciences, Faculty of Sciences, University of Amsterdam, Amsterdam, Netherlands.

Publikováno v: Frontiers in molecular neuroscience [Front Mol Neurosci] 2019 Feb 19; Vol. 12, pp. 31. Date of Electronic Publication: 2019 Feb 19 (Print Publication: 2019).