Výsledky vyhledávání - "Willems, P.H.G.M."

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Integrated High-Content Quantification of Intracellular ROS Levels and Mitochondrial Morphofunction

Autor: Sieprath, T., Corne, T.D., Willems, P.H.G.M., Koopman, W.J.H., Vos, W.H. De

Publikováno v: Advances in Anatomy Embryology and Cell Biology, 219, pp. 149-77
Advances in Anatomy Embryology and Cell Biology, 219, 149-77

Item does not contain fulltext Oxidative stress arises from an imbalance between the production of reactive oxygen species (ROS) and their removal by cellular antioxidant systems. Especially under pathological conditions, mitochondria constitute a re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::10ebb7afb9c2ed810b03cfe641f6004c
https://hdl.handle.net/2066/172829

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Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

Autor: Cheng, S.-C. Scicluna, B.P. Arts, R.J.W. Gresnigt, M.S. Lachmandas, E. Giamarellos-Bourboulis, E.J. Kox, M. Manjeri, G.R. Wagenaars, J.A.L. Cremer, O.L. Leentjens, J. Van Der Meer, A.J. Van De Veerdonk, F.L. Bonten, M.J. Schultz, M.J. Willems, P.H.G.M. Pickkers, P. Joosten, L.A.B. Van Der Poll, T. Netea, M.G.

The acute phase of sepsis is characterized by a strong inflammatory reaction. At later stages in some patients, immunoparalysis may be encountered, which is associated with a poor outcome. By transcriptional and metabolic profiling of human patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::4d6b2907c8b326e9efb4dbe7a21f5f9d
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3003750

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Live-cell assessment of mitochondrial reactive oxygen species using dihydroethidine

Autor: Forkink, M., Willems, P.H.G.M., Koopman, W.J.H., Grefte, S.

Publikováno v: Methods in Molecular Biology, 1264, pp. 161-9
Methods in Molecular Biology, 1264, 161-9

Item does not contain fulltext Reactive oxygen species (ROS) play an important role in both physiology and pathology. Mitochondria are an important source of the primary ROS superoxide. However, accurate detection of mitochondrial superoxide especial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4faca3c0ad2c3816069f901a65ddcdfa
https://hdl.handle.net/2066/153290

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Simultaneous quantification of oxidative stress and cell spreading using 5-(and-6)-chloromethyl-2',7'-dichlorofluorescein

Autor: Koopman, W.J.H., Verkaart, S.A.J., Emst-de Vries, S.E. van, Grefte, S., Smeitink, J.A.M., Willems, P.H.G.M.

Publikováno v: Cytometry. Part A, 69, 1184-92
Cytometry. Part A, 69, 12, pp. 1184-92

Contains fulltext : 50403.pdf (Publisher’s version ) (Closed access) BACKGROUND: Mitochondrial dysfunction may lead to increased oxidative stress and consequent changes in cell spreading. Here, we describe and validate a novel method for simultaneo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f2c20bd137c7f184962edb71c1639605
https://hdl.handle.net/2066/50403

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Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties

Autor: Nikolaisen, J., Nilsson, L.I., Pettersen, I.K., Willems, P.H.G.M., Lorens, J.B., Koopman, W.J.H., Tronstad, K.J.

Publikováno v: PLoS One, 9
PLoS One, 9, 7

Contains fulltext : 133871.pdf (Publisher’s version ) (Open Access) Mitochondrial morphology and function are coupled in healthy cells, during pathological conditions and (adaptation to) endogenous and exogenous stress. In this sense mitochondrial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::39f5ec8658f801b251e6215ebc2feb66
https://hdl.handle.net/2066/133871

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Akademický článek

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Effect of the aminosteroid, U73122, on Ca2+ uptake and release properties of rat liver microsomes

Autor: Moel, M.P. de, Put, F.H.M.M. van de, Vermegen, T.M.J.A., Pont, J.J.H.H.M. de, Willems, P.H.G.M.

Publikováno v: European Journal of Biochemistry, 234, 626-631. Springer verlag
European Journal of Biochemistry, 234, 626-631
European Journal of Biochemistry, 234, 2, pp. 626-631
European Journal of Biochemistry, 234, pp. 626-631

Contains fulltext : 21901___.PDF (Publisher’s version ) (Open Access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::32b4dd1acf3b58973be817cf6769aa55
https://hdl.handle.net/2066/264642

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Chapter 16 The use of fluorescence correlation spectroscopy to probe mitochondrial mobility and intramatrix protein diffusion

Autor: Willems, P.H.G.M., Swarts, H.G.P., Hink, M.A., Koopman, W.J.H.

Publikováno v: Methods in Enzymology . New York, 456, 287-302
Methods in Enzymology . New York, 456, pp. 287-302

Item does not contain fulltext Within cells, functional changes in mitochondrial metabolic state are associated with alterations in organelle mobility, shape, and configuration of the mitochondrial matrix. Fluorescence correlation spectroscopy (FCS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ee3ab3836a7514206812b8ab4311113d
http://hdl.handle.net/2066/80059

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