Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease

Autor: Lapperre, T. S., Snoeck-Stroband, J. B., Gosman, M. M. E., Jansen, D. F., Schadewijk, A., Thiadens, H. A., Vonk, J. M., Boezen, H. M., Ten Hacken, N. H. T., Sont, J. K., Rabe, K. F., Kerstjens, H. A. M., Hiemstra, P. S., Wim Timens, Postma, D. S., Sterk, P. J., Kauffman, H. F., Reus, D., Barentsen, M. D. W., Zeinstra-Smit, M., Luteijn, A. J., Molen, T., Ter Veen, G., Maaren, M. S., Veltman, C. A., Verbokkem, A., Verhage, I., Vink-Klooster, H. K., Gast-Strookman, J., Janssen, K., Schrumpf, J. A., Smit-Bakker, J., Stolk, J., Tiré, A. C. J. A., Veen, H., Wijffels, M. M. E., Willems, L. N. A., Mauad, T.

Publikováno v: Annals of internal medicine
Scopus-Elsevier
Annals of Internal Medicine, 151(8), 517-527. American College of Physicians
Annals of internal medicine, 151(8), 517-527. American College of Physicians

Background: Inhaled corticosteroids (ICSs) and long-acting β2-agonists (LABAs) are used to treat moderate to severe chronic obstructive pulmonary disease (COPD). Objective: To determine whether long-term ICS therapy, with and without LABAs, reduces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400201d08417b35cd94e9c5b9b5e6356
http://www.scopus.com/inward/record.url?scp=70350219119&partnerID=8YFLogxK

Smoking cessation and bronchial epithelial remodelling in COPD

Autor: Lapperre, Therese, Sont, Jacob K., van Schadewijk, Annemarie, Gosman, Margot M. E., Postma, Dirkje S., Bajema, Ingeborg M., Timens, Wim, Mauad, Thais, Hiemstra, Pieter S., Kauffman, H. F., de Reus, D., Boezen, H. M., Jansen, D. F., Vonk, J., Barentsen, M. D. W., Timens, W., Zeinstra-Smit, M., Luteijn, A. J., van der Molen, T., ter Veen, G., Gosman, M. M. E., ten Hacken, N. H. T., Kerstjens, H. A. M., van Maaren, M. S., Postma, D. S., Veltman, C. A., Verbokkem, A., Verhage, I., Vink-Kloosters, H. K., Snoeck-Stroband, J. B., Thiadens, H., Sont, J. K., Bajema, I., Gast-Strookman, J., Hiemstra, P. S., Janssen, K., Lapperre, T. S., Rabe, K. F., van Schadewijk, A., Schrumpf, J. A., Smit-Bakker, J., Stolk, J., Tire, A. C. J. A., van der Veen, H., Wijffels, M. M. E., Willems, L. N. A., Sterk, P. J., Mauad, T.

Publikováno v: Respiratory Research
Respiratory Research, 8:85. BioMed Central Ltd.
Respiratory research
Respiratory Research, Vol 8, Iss 1, p 85 (2007)

Background Chronic Obstructive Pulmonary Disease (COPD) is associated with bronchial epithelial changes, including squamous cell metaplasia and goblet cell hyperplasia. These features are partially attributed to activation of the epidermal growth fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de870a46914d9bd86964e62b8ad734e
https://hdl.handle.net/11370/88b66f0f-3773-4477-8902-477f5a7db8d1

Clinical control and histopathologic outcome of asthma when using aireway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL study Group

Autor: Sont, J. K., Willems, L. N., Bel, E. H., van Krieken, J. H., Vandenbroucke, J. P., Sterk, P. J.

Publikováno v: American Journal of Respiratory and Critical Care Medicine, 159, pp. 1043-1051
American Journal of Respiratory and Critical Care Medicine, 159, 1043-1051
American journal of respiratory and critical care medicine, 159(4 Part 1), 1043-1051. American Thoracic Society

According to international guidelines, the level and adjustment of antiinflammatory treatment for asthma are based solely on symptoms and lung function. We investigated whether a treatment strategy aimed at reducing airway hyperresponsiveness (AHR st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c48b32fc7c2f9a6f8397ea52ec9f44d5
https://hdl.handle.net/2066/185993

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Pretreatment serum lactate dehydrogenase as additional staging parameter in patients with small-cell lung carcinoma.

Autor: Stokkel, M. P. M., van Eck-Smit, B. L. F., Zwinderman, A. H., Willems, L. N. A., Pauwels, E. K. J.

Publikováno v: Journal of Cancer Research & Clinical Oncology; Apr1998, Vol. 124 Issue 3/4, p215-219, 5p