Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Willemina R. R. Geurts-Giele"'
Autor:
Martine Dumont, Nana Weber-Lassalle, Charles Joly-Beauparlant, Corinna Ernst, Arnaud Droit, Bing-Jian Feng, Stéphane Dubois, Annie-Claude Collin-Deschesnes, Penny Soucy, Maxime Vallée, Frédéric Fournier, Audrey Lemaçon, Muriel A. Adank, Jamie Allen, Janine Altmüller, Norbert Arnold, Margreet G. E. M. Ausems, Riccardo Berutti, Manjeet K. Bolla, Shelley Bull, Sara Carvalho, Sten Cornelissen, Michael R. Dufault, Alison M. Dunning, Christoph Engel, Andrea Gehrig, Willemina R. R. Geurts-Giele, Christian Gieger, Jessica Green, Karl Hackmann, Mohamed Helmy, Julia Hentschel, Frans B. L. Hogervorst, Antoinette Hollestelle, Maartje J. Hooning, Judit Horváth, M. Arfan Ikram, Silke Kaulfuß, Renske Keeman, Da Kuang, Craig Luccarini, Wolfgang Maier, John W. M. Martens, Dieter Niederacher, Peter Nürnberg, Claus-Eric Ott, Annette Peters, Paul D. P. Pharoah, Alfredo Ramirez, Juliane Ramser, Steffi Riedel-Heller, Gunnar Schmidt, Mitul Shah, Martin Scherer, Antje Stäbler, Tim M. Strom, Christian Sutter, Holger Thiele, Christi J. van Asperen, Lizet van der Kolk, Rob B. van der Luijt, Alexander E. Volk, Michael Wagner, Quinten Waisfisz, Qin Wang, Shan Wang-Gohrke, Bernhard H. F. Weber, Genome of the Netherlands Project, GHS Study Group, Peter Devilee, Sean Tavtigian, Gary D. Bader, Alfons Meindl, David E. Goldgar, Irene L. Andrulis, Rita K. Schmutzler, Douglas F. Easton, Marjanka K. Schmidt, Eric Hahnen, Jacques Simard
Publikováno v:
Cancers, Vol 14, Iss 14, p 3363 (2022)
Rare variants in at least 10 genes, including BRCA1, BRCA2, PALB2, ATM, and CHEK2, are associated with increased risk of breast cancer; however, these variants, in combination with common variants identified through genome-wide association studies, e
Externí odkaz:
https://doaj.org/article/5080cce8aedf47dfa6606539b6a2f607
Autor:
Ellis L. Eikenboom, Helena C. van Doorn, Winand N. M. Dinjens, Hendrikus J. Dubbink, Willemina R. R. Geurts-Giele, Manon C. W. Spaander, Carli M. J. Tops, Anja Wagner, Anne Goverde
Publikováno v:
Cancers, Vol 13, Iss 3, p 459 (2021)
Lynch syndrome (LS) is caused by pathogenic germline variants in DNA mismatch repair (MMR) genes, predisposing female carriers for endometrial cancer (EC) and ovarian cancer (OC). Since gynecological LS surveillance guidelines are based on little evi
Externí odkaz:
https://doaj.org/article/0a4492573895450ea9916954b0ada76e
Autor:
Paul Roepman, Danielle Cohen, Stephen P. Finn, Cathal O'Brien, Hein F.B.M. Sleddens, Kim Monkhorst, Karin Weijers, Guido M.J.M. Roemen, Isabelle C. Meijssen, Ernst-Jan M. Speel, Tom van Wezel, Winand N.M. Dinjens, Mirjam C. Boelens, H.J. Dubbink, Willemina R. R. Geurts-Giele, Jan H. von der Thüsen, Kris G. Samsom, Erik Thunnissen, Teodora Radonic
Publikováno v:
Radonic, T, Geurts-Giele, W R R, Samsom, K G, Roemen, G M J M, von der Thüsen, J H, Thunnissen, E, Meijssen, I C, Sleddens, H F B M, Dinjens, W N M, Boelens, M C, Weijers, K, Speel, E J M, Finn, S P, O'Brien, C, van Wezel, T, Cohen, D, Monkhorst, K, Roepman, P & Dubbink, H J 2021, ' RET Fluorescence In Situ Hybridization Analysis Is a Sensitive but Highly Unspecific Screening Method for RET Fusions in Lung Cancer ', Journal of Thoracic Oncology, vol. 16, no. 5, pp. 798-806 . https://doi.org/10.1016/j.jtho.2021.01.1619
Journal of Thoracic Oncology, 16(5), 798-806. Elsevier Science
Journal of Thoracic Oncology, 16(5), 798-806. International Association for the Study of Lung Cancer
Journal of Thoracic Oncology, 16(5), 798-806. Elsevier Science
Journal of Thoracic Oncology, 16(5), 798-806. International Association for the Study of Lung Cancer
Introduction: RET gene fusions are established oncogenic drivers in 1% of NSCLC. Accurate detection of advanced patients with RET fusions is essential to ensure optimal therapy choice. We investigated the performance of fluorescence in situ hybridiza
Autor:
Cindy Leeijen, Anne J. M. Loonen, Cornelis J. J. Huijsmans, Willemina R. R. Geurts-Giele, Johannes C van der Linden, Adriaan J. C. van den Brule
Publikováno v:
APMIS, 128(8), 497-505. Blackwell Publishing
Primary high-risk human papillomavirus (hrHPV) DNA testing has been introduced in several countries worldwide, including The Netherlands. The objective of this study was to compare three automated workflow procedures for hrHPV testing of which the hr
Autor:
Thüsen J.H. von der, Melinda A. Pruis, A-M.C. Dingemans, Willemina R. R. Geurts-Giele, Isabelle C. Meijssen, W. Dinjens, Marthe S. Paats, Hendrikus J. Dubbink, Martijn P. Lolkema, Joachim G.J.V. Aerts
Publikováno v:
Lung Cancer, 140, 46-54. Elsevier Ireland Ltd
Objectives The oncogenic MET exon 14 skipping mutation (METex14del) is described to drive 1.3 %–5.7 % of non-small-cell lung cancer (NSCLC) and multiple studies with cMET inhibitors show promising clinical responses. RNA-based analysis seems most o
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 16(7)
Autor:
Edwin Cuppen, Stef van Lieshout, Hendrikus J. Dubbink, Paul Roepman, Marloes Steehouwer, Manon M. H. Huibers, Jacobus J.M. van der Hoeven, Kim Monkhorst, Lieke Schoenmaker, Willemina R. R. Geurts-Giele, Mariëtte E.G. Kranendonk, Bauke Ylstra, Mirjam C. Boelens, Floris H. Groenendijk, Alexander Hoischen, Wendy W.J. de Leng, Ewart de Bruijn, Margaretha G. M. Roemer, Kris G. Samsom
Publikováno v:
Roepman, P, de Bruijn, E, van Lieshout, S, Schoenmaker, L, Boelens, M C, Dubbink, H J, Geurts-Giele, W R R, Groenendijk, F H, Huibers, M M H, Kranendonk, M E G, Roemer, M G M, Samsom, K G, Steehouwer, M, de Leng, W W J, Hoischen, A, Ylstra, B, Monkhorst, K, van der Hoeven, J J M & Cuppen, E 2021, ' Clinical Validation of Whole Genome Sequencing for Cancer Diagnostics ', Journal of Molecular Diagnostics, vol. 23, no. 7, pp. 816-833 . https://doi.org/10.1016/j.jmoldx.2021.04.011
Journal of Molecular Diagnostics, 23, 7, pp. 816-833
Journal of Molecular Diagnostics, 23, 816-833
Journal of Molecular Diagnostics, 23(7), 816-833. Association of Molecular Pathology
Journal of Molecular Diagnostics, 23, 7, pp. 816-833
Journal of Molecular Diagnostics, 23, 816-833
Journal of Molecular Diagnostics, 23(7), 816-833. Association of Molecular Pathology
Whole genome sequencing (WGS) using fresh frozen tissue and matched blood samples from cancer patients is becoming in reach as the most complete genetic tumor test. With a trend towards the availability of small biopsies and the need to screen an inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e77afd0b0074d49a789ea249d925a6
https://doi.org/10.1101/2020.10.29.20222091
https://doi.org/10.1101/2020.10.29.20222091
Autor:
Gerrit A. Meijer, Flora E. van Leeuwen, Johan Hoeksel, Willemina R. R. Geurts-Giele, Winand N.M. Dinjens, Peggy N. Atmodimedjo, Petur Snaebjornsson, Efraim H. Rosenberg, Berthe M.P. Aleman, Jelle ten Hoeve, Hein te Riele, Thomas W. van Ravesteyn, Monique E. van Leerdam, Lisanne S. Rigter
Publikováno v:
Gut, 67(3), 447-455. BMJ Publishing Group
Gut, 67, 447-455
Rigter, L S, Snaebjornsson, P, Rosenberg, E H, Atmodimedjo, P N, Aleman, B M, ten Hoeve, J, Geurts-Giele, W R, van Ravesteyn, T W, Hoeksel, J, Meijer, G A, te Riele, H, van Leeuwen, F E, Dinjens, W N & van Leerdam, M E 2018, ' Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment ', Gut, vol. 67, no. 3, pp. 447-455 . https://doi.org/10.1136/gutjnl-2016-312608
Gut, 67, 3, pp. 447-455
Gut, 67, 447-455
Rigter, L S, Snaebjornsson, P, Rosenberg, E H, Atmodimedjo, P N, Aleman, B M, ten Hoeve, J, Geurts-Giele, W R, van Ravesteyn, T W, Hoeksel, J, Meijer, G A, te Riele, H, van Leeuwen, F E, Dinjens, W N & van Leerdam, M E 2018, ' Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment ', Gut, vol. 67, no. 3, pp. 447-455 . https://doi.org/10.1136/gutjnl-2016-312608
Gut, 67, 3, pp. 447-455
ObjectiveHodgkin's lymphoma survivors who were treated with infradiaphragmatic radiotherapy or procarbazine-containing chemotherapy have a fivefold increased risk of developing colorectal cancer (CRC). This study aims to provide insight into the deve
Autor:
Tom van Wezel, Hendrikus J. Dubbink, Carel J. M. van Noesel, Judith W. M. Jeuken, Arja ter Elst, Leonie I. Kroeze, Daniëlle A M Heideman, Patricia J. T. A. Groenen, Ernst-Jan M. Speel, Bastiaan B J Tops, Cornelis J. J. Huijsmans, Astrid Eijkelenboom, Manon M. H. Huibers, Adrianus Johannes Christiaan van den Brule, Maartje J Vogel, Wendy W.J. de Leng, Esther Korpershoek, Anke van den Berg, Willemina R. R. Geurts-Giele, Floris H. Groenendijk, Winand N.M. Dinjens, Léon C van Kempen, Ed Schuuring, Marjolijn J. L. Ligtenberg, Petra M. Nederlof
Publikováno v:
Virchows Archiv, 474(6), 673-680. Springer, Cham
Virchows Archiv. An International Journal of Pathology, 474(6), 673-680. Springer-Verlag
Virchows Archives, 474, 673. Springer Verlag
Virchows Archiv. Springer Verlag
Virchows Archiv, 474(6), 673-680. SPRINGER
Virchows Archiv, 474, 673-680
Virchows Archiv, 474, 673-680. Springer Verlag
Virchows Archiv, 474, 6, pp. 673-680
Eijkelenboom, A, Tops, B B J, van den Berg, A, van den Brule, A J C, Dinjens, W N M, Dubbink, H J, Ter Elst, A, Geurts-Giele, W R R, Groenen, P J T A, Groenendijk, F H, Heideman, D A M, Huibers, M M H, Huijsmans, C J J, Jeuken, J W M, van Kempen, L C, Korpershoek, E, Kroeze, L I, de Leng, W W J, van Noesel, C J M, Speel, E-J M, Vogel, M J, van Wezel, T, Nederlof, P M, Schuuring, E & Ligtenberg, M J L 2019, ' Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics ', Virchows Archiv, vol. 474, pp. 673-680 . https://doi.org/10.1007/s00428-019-02555-3
Virchows Archiv
Virchows Archiv : an International Journal of Pathology, 474(6), 673-680. SPRINGER
Virchows Archiv. An International Journal of Pathology, 474(6), 673-680. Springer-Verlag
Virchows Archives, 474, 673. Springer Verlag
Virchows Archiv. Springer Verlag
Virchows Archiv, 474(6), 673-680. SPRINGER
Virchows Archiv, 474, 673-680
Virchows Archiv, 474, 673-680. Springer Verlag
Virchows Archiv, 474, 6, pp. 673-680
Eijkelenboom, A, Tops, B B J, van den Berg, A, van den Brule, A J C, Dinjens, W N M, Dubbink, H J, Ter Elst, A, Geurts-Giele, W R R, Groenen, P J T A, Groenendijk, F H, Heideman, D A M, Huibers, M M H, Huijsmans, C J J, Jeuken, J W M, van Kempen, L C, Korpershoek, E, Kroeze, L I, de Leng, W W J, van Noesel, C J M, Speel, E-J M, Vogel, M J, van Wezel, T, Nederlof, P M, Schuuring, E & Ligtenberg, M J L 2019, ' Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics ', Virchows Archiv, vol. 474, pp. 673-680 . https://doi.org/10.1007/s00428-019-02555-3
Virchows Archiv
Virchows Archiv : an International Journal of Pathology, 474(6), 673-680. SPRINGER
Next-generation sequencing (NGS) panel analysis on DNA from formalin-fixed paraffin-embedded (FFPE) tissue is increasingly used to also identify actionable copy number gains (gene amplifications) in addition to sequence variants. While guidelines for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb34cb11dbb64cc21ab611bcf3b6f06
https://dspace.library.uu.nl/handle/1874/392203
https://dspace.library.uu.nl/handle/1874/392203
Autor:
Anja van Rens, Willemina R. R. Geurts-Giele, Efraim H. Rosenberg, Fonnet E. Bleeker, Winand N.M. Dinjens, Monique E. van Leerdam
Publikováno v:
Molecular genetics & genomic medicine, 7(7):UNSP e699. John Wiley & Sons Inc.
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine, Vol 7, Iss 7, Pp n/a-n/a (2019)
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine, Vol 7, Iss 7, Pp n/a-n/a (2019)
textabstractBackground: Lynch syndrome (LS) is caused by germline mismatch repair (MMR) gene mutations. De novo MMR gene mutations are rare, and somatic mosaicism in LS is thought to be infrequent. We describe the first case of somatic mosaicism by a