Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Willemina Foppen"'
Autor:
Ofer Levy, Simon D. van Haren, Robert M. Hershberg, Peter Andersen, Lindsey R. Baden, Steven G. Reed, David J. Dowling, Dennis Christensen, Willemina Foppen
Publikováno v:
J Immunol
Due to functionally distinct cell-mediated immunity, newborns and infants are highly susceptible to infection with intracellular pathogens. Indeed, neonatal Ag-presenting dendritic cells (DCs) demonstrate impaired Th1 responses to many candidate adju
Autor:
Al Ozonoff, Raina N. Fichorova, Joe M. Beaurline, Dhohyung Kim, John P. Vasilakos, Cecily C. Midkiff, Willemina Foppen, Simon D. van Haren, Lynn Fresh, Terese B. Theriot, James Blanchard, Christy J. Mancuso, Mark A. Tomai, Annette Scheid, Dmitri Smirnov, David J. Dowling, Andrew A. Lackner, Margaret H. Gilbert, Xavier Alvarez, Ofer Levy, Pyone P. Aye, Ilana Bergelson
Publikováno v:
JCI insight. 2(6)
Infection is the most common cause of mortality in early life, and immunization is the most promising biomedical intervention to reduce this burden. However, newborns fail to respond optimally to most vaccines. Adjuvantation is a key approach to enha
Publikováno v:
The Journal of Immunology. 192:204.5-204.5
Due to impairments in cell-mediated immunity, newborns are markedly susceptible to infection with intracellular pathogens. Impaired newborn immunity includes a reduced response to Toll-like Receptor agonists (TLRAs) by dendritic cells (DCs), placing