Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Willemijn M. Gommans"'
Autor:
Hamid el Azzouzi, Andreia P. Vilaça, Dries A. M. Feyen, Willemijn M. Gommans, Roel A. de Weger, Pieter A. F. Doevendans, Joost P. G. Sluijter
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Background: Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA-editing enzyme that is involved in several functions including the deamination of adenosine to inosine, RNA interference (RNAi) mechanisms and microRNA (miRNA) processin
Externí odkaz:
https://doaj.org/article/66d621fa95dc42239d8bdc45ae357a35
Autor:
Jos B. Poell, Rick J. van Haastert, Thijs de Gunst, Iman J. Schultz, Willemijn M. Gommans, Mark Verheul, Francesco Cerisoli, Andre A.F.L. van Puijenbroek, Paula I. van Noort, Gregoire P. Prevost, Roel Q. J. Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1 (2013)
PLoS ONE, Vol 8, Iss 1 (2013)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1081e862857698711587d6c6254b4a8
https://pubmed.ncbi.nlm.nih.gov/22927992
https://pubmed.ncbi.nlm.nih.gov/22927992
Autor:
Willemijn M. Gommans
Publikováno v:
Seminars in Cell & Developmental Biology. 23:251-257
An important epigenetic mechanism in mammals is adenosine deamination, which generates transcriptome variety through the conversion of single adenosines into inosines in RNA molecules. Inosine is interpreted as guanosine by the translational machiner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a338b5854bc4df36b5049adc0f5075a8
https://doi.org/10.1016/j.semcdb.2011.09.018
https://doi.org/10.1016/j.semcdb.2011.09.018
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 822
Our understanding of the importance of noncoding RNA molecules is steadily growing. One such important class of RNA molecules are microRNAs (miRNAs). These tiny RNAs fulfill important functions in cellular behavior by influencing the protein output l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c3fe4e35082dbb2aeaa64f20aa1dc35
https://pubmed.ncbi.nlm.nih.gov/22144188
https://pubmed.ncbi.nlm.nih.gov/22144188
Autor:
Jos B, Poell, Rick J, van Haastert, Thijs, de Gunst, Iman J, Schultz, Willemijn M, Gommans, Mark, Verheul, Francesco, Cerisoli, Andre A F L, van Puijenbroek, Paula I, van Noort, Gregoire P, Prevost, Roel Q J, Schaapveld, Edwin, Cuppen
Publikováno v:
PLoS ONE
PLoS One, 7(8). Public Library of Science
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
PLoS One, 7(8). Public Library of Science
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ca73bb2d5645163f919233ba9b9703
https://pubmed.ncbi.nlm.nih.gov/29364961
https://pubmed.ncbi.nlm.nih.gov/29364961
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 786
High-throughput sequencing has allowed for a comprehensive small RNA (sRNA) expression analysis of numerous tissues in a diverse set of organisms. The computational analysis of the millions of generated sequencing reads has led to the discovery of no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1065a3f4860501ddb046e515567f6a3c
https://pubmed.ncbi.nlm.nih.gov/21938626
https://pubmed.ncbi.nlm.nih.gov/21938626
Autor:
Astrid E, Visser, Pernette J, Verschure, Willemijn M, Gommans, Hidde J, Haisma, Marianne G, Rots
Publikováno v:
Advances in genetics. 56
Increasing knowledge about the influence of dysregulated gene expression in causing numerous diseases opens up new possibilities for the development of innovative therapeutics. In this chapter, we first describe different mechanisms of misregulated g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a17cefe35d611d10ef8a00eb66625f9
https://pubmed.ncbi.nlm.nih.gov/16735157
https://pubmed.ncbi.nlm.nih.gov/16735157
Publikováno v:
Encyclopedia of Medical Genomics and Proteomics ISBN: 0203997352
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63454cf45a3f9d92be475f193904e15e
https://doi.org/10.3109/9780203997352.006
https://doi.org/10.3109/9780203997352.006
Autor:
Francesco Cerisoli, R.Q.J. Schaapveld, Grégoire Pierre André Prevost, P.I. van Noort, Raymond M. Schiffelers, Negar Babae, M. Bouraüai, J.R. van Beijnum, A.W. Griffioen, Willemijn M. Gommans
Publikováno v:
European Journal of Cancer. 48:S251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37843b4840c5bf866aafbc534478a08d
https://doi.org/10.1016/s0959-8049(12)71654-4
https://doi.org/10.1016/s0959-8049(12)71654-4
Autor:
Paula I. van Noort, Negar Babae, Jos B. Poell, Meriem Bourajjaj, Suzana Vidic, Judy R. van Beijnum, Rick J. van Haastert, Iman Schultz, Thijs de Gunt, Onno van Hooij, Gerald W. Verhaegh, Willemijn M. Gommans, Francesco Cerisoli, Mark Verheul, Raymond M. Schiffelers, Arjan W. Griffioen, Jack A. Schalken, Eugene Berezikov, Edwin Cuppen, Roel QJ Schaapveld, Gregoire P. Prevost
Publikováno v:
Cancer Research. 72:1112-1112
microRNA (miRNA) genes transcribed by RNA polymerase II generate small noncoding miRNAs of 18 to 24 nucleotides after maturation process. The mature miRNAs and their associated isomirs specifically bind to different mRNA transcripts, resulting in dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68d541876cd121ed78b947f634925e91
https://doi.org/10.1158/1538-7445.am2012-1112
https://doi.org/10.1158/1538-7445.am2012-1112