Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Willemijn M. Gommans"'
Autor:
Hamid el Azzouzi, Andreia P. Vilaça, Dries A. M. Feyen, Willemijn M. Gommans, Roel A. de Weger, Pieter A. F. Doevendans, Joost P. G. Sluijter
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Background: Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA-editing enzyme that is involved in several functions including the deamination of adenosine to inosine, RNA interference (RNAi) mechanisms and microRNA (miRNA) processin
Externí odkaz:
https://doaj.org/article/66d621fa95dc42239d8bdc45ae357a35
Autor:
Jos B Poell, Rick J van Haastert, Thijs de Gunst, Iman J Schultz, Willemijn M Gommans, Mark Verheul, Francesco Cerisoli, Andre A F L van Puijenbroek, Paula I van Noort, Gregoire P Prevost, Roel Q J Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE, Vol 8, Iss 1 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0043569.].
Externí odkaz:
https://doaj.org/article/809690cb2b36494aae39d53295789ec4
Autor:
Jos B Poell, Rick J van Haastert, Thijs de Gunst, Iman J Schultz, Willemijn M Gommans, Mark Verheul, Francesco Cerisoli, Andre A F L van Puijenbroek, Paula I van Noort, Gregoire P Prevost, Roel Q J Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Externí odkaz:
https://doaj.org/article/d40c736567e848e5920930dd9625597e
Autor:
Stefan Maas, Willemijn M Gommans
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4225 (2009)
The post-transcriptional processing of pre-mRNAs by RNA editing contributes significantly to the complexity of the mammalian transcriptome. RNA editing by site-selective A-to-I modification also regulates protein function through recoding of genomica
Externí odkaz:
https://doaj.org/article/6a93b5a74a474cadbe446e360969eb62
Autor:
Jos B. Poell, Rick J. van Haastert, Thijs de Gunst, Iman J. Schultz, Willemijn M. Gommans, Mark Verheul, Francesco Cerisoli, Andre A.F.L. van Puijenbroek, Paula I. van Noort, Gregoire P. Prevost, Roel Q. J. Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1 (2013)
PLoS ONE, Vol 8, Iss 1 (2013)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Autor:
Willemijn M. Gommans
Publikováno v:
Seminars in Cell & Developmental Biology. 23:251-257
An important epigenetic mechanism in mammals is adenosine deamination, which generates transcriptome variety through the conversion of single adenosines into inosines in RNA molecules. Inosine is interpreted as guanosine by the translational machiner
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 822
Our understanding of the importance of noncoding RNA molecules is steadily growing. One such important class of RNA molecules are microRNAs (miRNAs). These tiny RNAs fulfill important functions in cellular behavior by influencing the protein output l
Autor:
Jos B, Poell, Rick J, van Haastert, Thijs, de Gunst, Iman J, Schultz, Willemijn M, Gommans, Mark, Verheul, Francesco, Cerisoli, Andre A F L, van Puijenbroek, Paula I, van Noort, Gregoire P, Prevost, Roel Q J, Schaapveld, Edwin, Cuppen
Publikováno v:
PLoS ONE
PLoS One, 7(8). Public Library of Science
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
PLoS One, 7(8). Public Library of Science
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 786
High-throughput sequencing has allowed for a comprehensive small RNA (sRNA) expression analysis of numerous tissues in a diverse set of organisms. The computational analysis of the millions of generated sequencing reads has led to the discovery of no
Autor:
Astrid E, Visser, Pernette J, Verschure, Willemijn M, Gommans, Hidde J, Haisma, Marianne G, Rots
Publikováno v:
Advances in genetics. 56
Increasing knowledge about the influence of dysregulated gene expression in causing numerous diseases opens up new possibilities for the development of innovative therapeutics. In this chapter, we first describe different mechanisms of misregulated g