Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Willemijn B. Breunis"'
Autor:
Silvia Pomella, Sara G. Danielli, Rita Alaggio, Willemijn B. Breunis, Ebrahem Hamed, Joanna Selfe, Marco Wachtel, Zoe S. Walters, Beat W. Schäfer, Rossella Rota, Janet M. Shipley, Simone Hettmer
Publikováno v:
Cancers, Vol 15, Iss 10, p 2823 (2023)
Rhabdomyosarcoma (RMS), the most common soft-tissue sarcoma in children and adolescents, represents an aberrant form of skeletal muscle differentiation. Both skeletal muscle development, as well as regeneration of adult skeletal muscle are governed b
Externí odkaz:
https://doaj.org/article/27e4946284454140834217ad2d8b7fa9
Autor:
Gabriele Manzella, Leonie D. Schreck, Willemijn B. Breunis, Jan Molenaar, Hans Merks, Frederic G. Barr, Wenyue Sun, Michaela Römmele, Luduo Zhang, Joelle Tchinda, Quy A. Ngo, Peter Bode, Olivier Delattre, Didier Surdez, Bharat Rekhi, Felix K. Niggli, Beat W. Schäfer, Marco Wachtel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Patient-specific precision medicine approaches are important for future cancer therapies. Here, the authors show that functional drug profiling with Rhabdomyosarcoma cells isolated from PDX and primary patient tumors uncovers patient-specific vulnera
Externí odkaz:
https://doaj.org/article/e1a776112ff34407a13275f886ecd3a9
Autor:
Sietse Q. Nagelkerke, Carline E. Tacke, Willemijn B. Breunis, Michael W. T. Tanck, Judy Geissler, Eileen Png, Long T. Hoang, Joris van der Heijden, Ahmad N. M. Naim, Rae S. M. Yeung, Michael L. Levin, Victoria J. Wright, David P. Burgner, Anne-Louise Ponsonby, Justine A. Ellis, Rolando Cimaz, Chisato Shimizu, Jane C. Burns, Karin Fijnvandraat, C. Ellen van der Schoot, Timo K. van den Berg, Martin de Boer, Sonia Davila, Martin L. Hibberd, Taco W. Kuijpers, The International Kawasaki Disease Genetics Consortium, Nagib Dahdah, Isabelle Kone-Paut
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The human Fc-gamma receptors (FcγRs) link adaptive and innate immunity by binding immunoglobulin G (IgG). All human low-affinity FcγRs are encoded by the FCGR2/3 locus containing functional single nucleotide polymorphisms (SNPs) and gene copy numbe
Externí odkaz:
https://doaj.org/article/d7250016b76748308206a393860e611b
Autor:
Christoph Bauer, Meret Quante, Willemijn B. Breunis, Carla Regina, Michaela Schneider, Geoffroy Andrieux, Oliver Gorka, Olaf Groß, Melanie Boerries, Bernd Kammerer, Simone Hettmer
Publikováno v:
Cancers, Vol 13, Iss 3, p 412 (2021)
Amino acids are integral components of cancer metabolism. The non-essential amino acid asparagine supports the growth and survival of various cancer cell types. Here, different mass spectrometry approaches were employed to identify lower aspartate le
Externí odkaz:
https://doaj.org/article/c249bd9822f3450a8c71c5a7ff1364ae
Autor:
Roelof van Ewijk, Bas Vaarwerk, Willemijn B. Breunis, Reineke A. Schoot, Simone A. J. ter Horst, Rick R. van Rijn, Johanna H. van der Lee, Johannes H. M. Merks
Publikováno v:
Cancers, Vol 13, Iss 3, p 510 (2021)
Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood. Results of clinical trials, with three-year event-free and overall survival as primary outcomes, often take 7 to 10 years. Identification of an early surrogate biomarker, predictiv
Externí odkaz:
https://doaj.org/article/2a0cb3dba9c64517aba9eb0f97279c10
Autor:
Frank C. P. Holstege, Jarno Drost, Ruben van Boxtel, Marc van de Wetering, Jan J. Molenaar, Patrick Kemmeren, Jayne Y. Hehir-Kwa, Bastiaan B. J. Tops, Max M. van Noesel, Johannes H. M. Merks, Uta Flucke, Laura S. Hiemcke-Jiwa, Sheila Terwisscha van Scheltinga, Rutger R. G. Knops, Marc van Tuil, Karin P. S. Langenberg, Selma Eising, M. Emmy M. Dolman, Alex Janse, Hinri H. D. Kerstens, Camilla Calandrini, Freek Manders, Jeff DeMartino, Mariël Brok, Ewa Frazer-Mendelewska, Willemijn B. Breunis, Terezinha de Souza, Marian J. A. Groot Koerkamp, Michael T. Meister
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d6c1a1dd7c26ccd4397c1f88597b5e
https://doi.org/10.15252/rc.2022721694
https://doi.org/10.15252/rc.2022721694
Autor:
Bas Vaarwerk, Willemijn B Breunis, Lianne M Haveman, Bart de Keizer, Nina Jehanno, Lise Borgwardt, Rick R van Rijn, Henk van den Berg, Jérémie F Cohen, Elvira C van Dalen, Johannes HM Merks
Publikováno v:
The Cochrane Library
Cochrane Database Syst Rev
Cochrane Database Syst Rev
BACKGROUND: Rhabdomyosarcoma (RMS) is the most common paediatric soft‐tissue sarcoma and can emerge throughout the whole body. For patients with newly diagnosed RMS, prognosis for survival depends on multiple factors such as histology, tumour site,
Autor:
Henk van den Berg, Willemijn B. Breunis, Lianne M. Haveman, Leontien C. M. Kremer, Uta Dirksen, Elvira C. van Dalen, Roelof van Ewijk, Johannes Hm Merks
Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
Background Ewing sarcomas are solid tumours of the bone and soft tissue, that usually affect children, adolescents, and young adults. The incidence is about three cases per million a year, with a peak incidence at 12 years of age. Metastatic disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75626b2ad7e6b5ae781132f112ee10b1
https://europepmc.org/articles/PMC8428235/
https://europepmc.org/articles/PMC8428235/
Autor:
Henk van den Berg, Willemijn B. Breunis, Uta Dirksen, Elvira C. van Dalen, J.H.M. Merks, Heribert Jürgens, Leontien C. M. Kremer, Lianne M. Haveman
Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
BACKGROUND: Ewing sarcoma is a solid tumour, which is the second most common primary bone malignancy in children, often occurring in the long bones and pelvis. An incidence rate of 4.5 per million a year is reported, with a peak incidence of 11 per m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854cc5c5f3fe9cd2cc89f87e34f5156d
https://doi.org/10.5167/uzh-212918
https://doi.org/10.5167/uzh-212918
Autor:
Bas Vaarwerk, Simone A. J. ter Horst, Roelof van Ewijk, Rick R. van Rijn, Reineke A. Schoot, Johannes H. M. Merks, Willemijn B. Breunis, Johanna H. van der Lee
Publikováno v:
Cancers
Cancers, Vol 13, Iss 510, p 510 (2021)
Cancers, Vol 13, Iss 510, p 510 (2021)
Simple Summary Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood. At diagnosis, tumor and patient characteristics determine the prognosis and subsequent treatment stratification. There are currently no early biomarkers that identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8f75d7ebfd748913d34d6fa82c70ac
https://doi.org/10.5167/uzh-212920
https://doi.org/10.5167/uzh-212920