Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Willem T. Peppler"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The gastrointestinal tract participates in maintaining metabolic homeostasis in part through nutrient-sensing and subsequent gut-brain signalling. Here the authors review the role of small intestinal nutrient-sensing in regulation of energy intake an
Externí odkaz:
https://doaj.org/article/a95c8ae22f0042f1b3ef962d4051972d
Autor:
Logan K. Townsend, Kyle D. Medak, Willem T. Peppler, Grace M. Meers, R. Scott Rector, Paul J. LeBlanc, David C. Wright
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1236-1249 (2019)
The relationship between liver interleukin-6 (IL-6) resistance following high-fat diet (HFD)-induced obesity and glucose intolerance is unclear. The purpose of this study was to assess the temporal development of hepatic IL-6 resistance and the role
Externí odkaz:
https://doaj.org/article/90a209a65e0742428bfa9d696f4d8b68
Autor:
Daniel M. Marko, Michael S. Finch, Alex J. T. Yang, Laura N. Castellani, Willem T. Peppler, David C. Wright, Rebecca E. K. MacPherson
Publikováno v:
Journal of Applied Physiology. 134:1115-1123
It is becoming evident that exercise modulates APP processing and can reduce amyloid-beta (Aβ) peptide production. Our data help to explain this phenomenon by highlighting IL-6 as an exercise-induced factor that lowers pathological APP processing. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c8dce3d069816314330f57855e37143
https://doi.org/10.1152/japplphysiol.00520.2022
https://doi.org/10.1152/japplphysiol.00520.2022
Autor:
Carly M. Knuth, David C. Wright, Hesham Shamshoum, Logan K. Townsend, Willem T. Peppler, Kyle D. Medak, Greg L. McKie
Publikováno v:
The Journal of Physiology. 597:4581-4600
Key points Mice are commonly housed at room temperatures below their thermoneutral zone meaning they are exposed to chronic thermal stress. Endurance exercise induces browning and mitochondrial biogenesis in white adipose tissue of rodents, but there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07bb29ed732c4a0d80d6c285f6fa14c
https://doi.org/10.1113/jp278221
https://doi.org/10.1113/jp278221
Autor:
David C. Wright, R. Scott Rector, Logan K. Townsend, Paul J. LeBlanc, Willem T. Peppler, Grace M. Meers, Kyle D. Medak
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1236-1249 (2019)
J Lipid Res
J Lipid Res
The relationship between liver interleukin-6 (IL-6) resistance following high-fat diet (HFD)-induced obesity and glucose intolerance is unclear. The purpose of this study was to assess the temporal development of hepatic IL-6 resistance and the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ec8df8685f450fcdc4dd63eb2b81c4
https://doi.org/10.1194/jlr.m092510
https://doi.org/10.1194/jlr.m092510
Autor:
Scott Frendo-Cumbo, Logan K. Townsend, Jared Root-McCaig, David C. Wright, Maureen J. Charron, Laura Castellani, Charles D. Sutton, Kyle D. Medak, Willem T. Peppler, Rebecca E. K. MacPherson
Publikováno v:
Medicine & Science in Sports & Exercise. 51:1116-1125
Introduction Follistatin (FST) is a protein with numerous biological roles and was recently identified as an exercise-inducible hepatokine; however, the signals that regulate this are not well understood. The purpose of this study was to delineate po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672ad8381b4b4426d97451e6929fe0ca
https://doi.org/10.1249/mss.0000000000001893
https://doi.org/10.1249/mss.0000000000001893
Autor:
David C. Wright, Willem T. Peppler, Kyle D. Medak, Logan K. Townsend, Maureen J. Charron, Carly M. Knuth
Publikováno v:
The FASEB Journal. 33:4824-4835
Various endocrine factors contribute to cold-induced white adipose tissue (WAT) browning, but glucagon has largely been ignored. The purpose of the current investigation was to determine if glucagon was required for the effects of cold on WAT brownin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0998b9d6b2f79d35e52cf494a344cd
https://doi.org/10.1096/fj.201802048rr
https://doi.org/10.1096/fj.201802048rr
Autor:
Logan K. Townsend, Matthew R. Panasevich, Grace M. Meers, Willem T. Peppler, R. Scott Rector, Rebecca E. K. MacPherson, David C. Wright
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 316:G166-G178
Obesity can lead to impairments in hepatic glucose and insulin homeostasis, and although exercise is an effective treatment, the molecular targets remain incompletely understood. As IL-6 is an exercise-inducible cytokine, we aimed to identify whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33060457a44db69182f291469e56ee4
https://doi.org/10.1152/ajpgi.00097.2018
https://doi.org/10.1152/ajpgi.00097.2018
Autor:
Rebecca E. K. MacPherson, Willem T. Peppler, Michael S. Finch, Laura Castellani, Daniel M. Marko, David C. Wright
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34f0077533d2ef7b58f27afa80ba3f75
https://doi.org/10.1096/fasebj.2021.35.s1.03304
https://doi.org/10.1096/fasebj.2021.35.s1.03304
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The gastrointestinal tract maintains energy and glucose homeostasis, in part through nutrient-sensing and subsequent signaling to the brain and other tissues. In this review, we highlight the role of small intestinal nutrient-sensing in metabolic hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82aaf79cd0f3caa889304954a277b489
https://doi.org/10.1038/s41467-021-21235-y
https://doi.org/10.1038/s41467-021-21235-y