Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Willem P. de Lange"'
Autor:
Kai-Chun Yang, MD, Astrid Breitbart, MD, Willem J. De Lange, PhD, Peter Hofsteen, PhD, Akiko Futakuchi-Tsuchida, BS, Joy Xu, MSE, Cody Schopf, BS, Maria V. Razumova, PhD, Alex Jiao, PhD, Robert Boucek, MD, Lil Pabon, PhD, Hans Reinecke, PhD, Deok-Ho Kim, PhD, J. Carter Ralphe, MD, Michael Regnier, PhD, Charles E. Murry, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 728-740 (2018)
Summary: A novel myosin heavy chain 7 mutation (E848G) identified in a familial cardiomyopathy was studied in patient-specific induced pluripotent stem cell–derived cardiomyocytes. The cardiomyopathic human induced pluripotent stem cell–derived c
Externí odkaz:
https://doaj.org/article/55e66573abed49ff8e6ea65cc4f0d1b0
Autor:
Emily Farrell, Annie E. Armstrong, Adrian C. Grimes, Francisco J. Naya, Willem J. de Lange, J. Carter Ralphe
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Rationale: With a prevalence of 1 in 200 individuals, hypertrophic cardiomyopathy (HCM) is thought to be the most common genetic cardiac disease, with potential outcomes that include severe hypertrophy, heart failure, and sudden cardiac death (SCD).
Externí odkaz:
https://doaj.org/article/aa5f89a96b0e415887f32229e9a503f7
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Rationale: Hypertrophic cardiomyopathy (HCM) occurs in ~0.5% of the population and is a leading cause of sudden cardiac death (SCD) in young adults. Cardiomyocyte hypertrophy has been the accepted mechanism for cardiac enlargement in HCM, but the ear
Externí odkaz:
https://doaj.org/article/9f39d2ae1b2b4d36b124aec904b277e3
Autor:
Willem P. de Lange, Karin R. Bryan, Conrad A. Pilditch, Dorothea Seeger, Kai Bischof, Daniel R. Pratt, Janet F. Bornman, Mariana Coppede Cussioli
Publikováno v:
Geo-Marine Letters. 40:217-225
The underwater light regime is fundamental to the ecological health of aquatic systems because it is a limiting factor for photosynthesis in marine plants such as seagrasses. Although seagrass meadows are a key component of coastal systems, their sur
Autor:
Stefan Kreiter, Tobias Mörz, Max Oke Kluger, M. Ehsan Jorat, Willem P. de Lange, Thomas Robertson, David J. Lowe, Vicki G. Moon
Publikováno v:
Landslides. 17:267-281
Rainfall is one of the most important triggers of slope failure. Weathered pyroclastic (tephra) deposits are especially vulnerable to slope failure because they commonly form slopes of high porosity and high clay content. Empirically derived threshol
Publikováno v:
Geo-Marine Letters. 40:227-241
Based on the analysis of 14 short sediment cores, we present new insights into the distribution of surficial sediments in the central Hauraki Gulf, a semi-enclosed coastal embayment on the northeast coast of New Zealand’s North Island. We identify
Autor:
Mariana Coppede Cussioli, Willem P. de Lange, Karin R. Bryan, Kai Bischof, Conrad A. Pilditch
Publikováno v:
Ocean & Coastal Management. 174:25-37
Benthic plants such as seagrasses rely on light availability, which is controlled by light attenuation in the water column. Elevated suspended sediment within estuaries strongly influences light attenuation and is governed by the recent history of na
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3128 (2008)
Value estimates of ecosystem goods and services are useful to justify the allocation of resources towards conservation, but inconclusive estimates risk unsustainable resource allocations. Here we present replacement costs as a more accurate value est
Externí odkaz:
https://doaj.org/article/a79152e906cd4864a5d2e33b1279213d
Publikováno v:
New Zealand Journal of Geology and Geophysics. 60:392-409
Tauranga Harbour is a major economic centre and home to New Zealand’s largest port. Despite the importance of the harbour basin, and especially of the shipping channel, the subsurface stratigraphy ...
Autor:
Willem P. de Lange, Tobias Kulgemeyer, Karin R. Bryan, Tilo von Dobeneck, Hendrik Müller, Christopher N. Battershill
Publikováno v:
Marine Geology. 383:78-98
Magnetic susceptibility and electric conductivity within the uppermost meter of the seafloor were measured with high resolution along 33 coast-normal profiles in the Bay of Plenty (New Zealand), using the recently developed electromagnetic benthic pr