Intradialytic Complement Activation Precedes the Development of Cardiovascular Events in Hemodialysis Patients

Autor: Felix Poppelaars, Mariana Gaya da Costa, Bernardo Faria, Stefan P. Berger, Solmaz Assa, Mohamed R. Daha, José Osmar Medina Pestana, Willem J. van Son, Casper F. M. Franssen, Marc A. Seelen

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. However, HD patients have markedly increased rates of cardiovascular morbidity and mortality. Previously, a link between the complement system and car

Externí odkaz: https://doaj.org/article/2a55b90e353d4e32b9bf457e79e8b293

Longitudinal monitoring of BKPyV miRNA levels in kidney transplant recipients with BKPyV-related pathology reflects viral DNA levels and remain high in viremia patients after clearance of viral DNA

Autor: Willem B. van Doesum, Lilli Gard, Laura W. D. Knijff, Hubert G. M. Niesters, Willem J. van Son, Coen A. Stegeman, Anke van den Berg, Henk Groen, Jacob van den Born, Annelies Riezebos‐Brilman, Jan Stephan Sanders

Publikováno v: Transplant Infectious Disease, 24(6):e13927. Wiley-Blackwell

Introduction: It is unclear whether polyomavirus BK (BKPyV) microribonucleic acid (miRNA) measurement has additional diagnostic and predictive value in kidney transplant recipients (KTR) as compared to current methods of monitoring BKPyV DNA loads. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4961f4f33ed5cd31883287a84f542de5
https://research.rug.nl/en/publications/57b3df3c-de7c-41cd-8069-dfa96b13185c

High human cytomegalovirus DNAemia early post-transplantation associates with irreversible and progressive loss of renal function - a retrospective study

Autor: Arjan Diepstra, Annelies Riezebos-Brilman, Willem van Doesum, Lilli Rurenga-Gard, Jacob van den Born, Rik van Bergen, Willem J. van Son, Wouter T Lollinga, Jan-Stephan F. Sanders, Hubert G. M. Niesters, Judith M. Vonk

Publikováno v: Transplant International. 30:817-826

Transplant recipients are prone to viral infections, which could affect renal transplantation outcome. Our aim was to assess the effects of early human cytomegalovirus (CMV) DNAemia on transplant renal function. A total of 264 (age 50.9 ± 13.5; male

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ceb629f49f42122ccc0bf5bc4dd7dc
https://doi.org/10.1111/tri.12972

Assessment of Cotinine Reveals a Dose-Dependent Effect of Smoking Exposure on Long-term Outcomes After Renal Transplantation

Autor: Stephan J. L. Bakker, Douwe Postmus, Willem J. van Son, Merel E. Hellemons, Gerjan Navis, Anneke C. Muller Kobold, Rijk O. B. Gans, Marc A. Seelen, Jan-Stephan F. Sanders

Publikováno v: Transplantation, 99(9), 1926-1932. LIPPINCOTT WILLIAMS & WILKINS

BACKGROUND: Smoking is a risk factor for poor late outcomes in renal transplant recipients (RTR). Smoking exposure can be assessed by self-report and cotinine measurements. We investigated whether use of cotinine as a biomarker for smoking exposure c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf35bd827141ed9c0dd8d3887da479ad
https://doi.org/10.1097/tp.0000000000000636

Human Cytomegalovirus-Encoded Receptor US28 Is Expressed in Renal Allografts and Facilitates Viral Spreading In Vitro

Autor: Martine J. Smit, Jan-Luuk Hillebrands, Arjan Diepstra, Afsar Rahbar, Belghis Davoudi, Cecilia Söderberg-Nauclér, Martin C. Harmsen, Jacob van den Born, Jan-Stephan F. Sanders, Wouter T Lollinga, Gwenda F Vasse, Raymond H. de Wit, Willem J. van Son, Annelies Riezebos-Brilman

Publikováno v: Transplantation, 101(3), 531-540. LIPPINCOTT WILLIAMS & WILKINS
Transplantation, 101(3), 531-540. Lippincott Williams and Wilkins
Lollinga, W T, de Wit, R H, Rahbar, A, Vasse, G F, Davoudi, B, Diepstra, A, Riezebos-Brilman, A, Harmsen, M C, Hillebrands, J-L, Söderberg-Naucler, C, van Son, W J, Smit, M J, Sanders, J-S & van den Born, J 2017, ' Human cytomegalovirus-encoded receptor US28 is expressed in renal allografts and facilitates viral spreading in vitro. ', Transplantation, vol. 101, no. 3, pp. 531-540 . https://doi.org/10.1097/TP.0000000000001289

BACKGROUND: Renal transplantation is the preferred treatment for patients with end-stage renal disease. Human cytomegalovirus (HCMV) activation is associated with decreased renal graft function and survival. Human cytomegalovirus encodes several immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004c9f292adb5917021d945226c8d4a7
https://research.rug.nl/en/publications/519fd4ec-0935-4e55-968a-c5f3cf28e304