Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Willem A. van Gool"'
Autor:
Jakob L. Schroevers, Marieke P. Hoevenaar-Blom, Wim B. Busschers, Monika Hollander, Willem A. Van Gool, Edo Richard, Jan Willem Van Dalen, Eric P. Moll van Charante
Publikováno v:
The Lancet Regional Health. Europe, Vol 42, Iss , Pp 100927- (2024)
Summary: Background: Hypertension is a modifiable risk factor for dementia affecting over 70% of individuals older than 60. Lowering dementia risk through preferential treatment with antihypertensive medication (AHM) classes that are otherwise equiva
Externí odkaz:
https://doaj.org/article/986038d5becf47d0adfe10fa948904ca
Autor:
Inge C. M. Hoogland, Jutka Yik, Dunja Westhoff, Joo-Yeon Engelen-Lee, Merche Valls Seron, Wing Kit Man, Judith H. P. M. Houben-Weerts, Michael W. T. Tanck, David J. van Westerloo, Tom van der Poll, Willem A. van Gool, Diederik van de Beek
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background Development of neurodegeneration in older people has been associated with microglial cell activation triggered by systemic infection. We hypothesize that α7 nicotinic acetylcholine receptor (α7nAChR) plays an important role in r
Externí odkaz:
https://doaj.org/article/63bb8819a83d44c1a3250a713782a01a
Autor:
Letty Oudewortel, Willem A. van Gool
Publikováno v:
Tijdschrift voor Gerontologie en Geriatrie, Iss 4 (2020)
Samenvatting Delier is een veel voorkomende ernstige complicatie bij dementie, die gepaard gaat met een slechte prognose en grote belasting van zowel mantelzorger als professionele zorgverleners. Tijdige en goede zorg voor patiënten met delier bij d
Externí odkaz:
https://doaj.org/article/676bed9715b944ed9752ac836b646cb2
Autor:
Tessa van Middelaar, Marieke P. Hoevenaar-Blom, Willem A. van Gool, Eric P. Moll van Charante, Jan-Willem van Dalen, Kay Deckers, Sebastian Köhler, Edo Richard
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Selecting high-risk participants for dementia prevention trials based on a modifiable dementia risk score may be advantageous, as it increases the opportunity for intervention. We studied whether a multi-domain intervention can pr
Externí odkaz:
https://doaj.org/article/9c0b0d106d9a402ea4200867095850ca
Autor:
Inge C.M. Hoogland, Dunja Westhoff, Joo-Yeon Engelen-Lee, Mercedes Valls Seron, Judith H.M.P. Houben-Weerts, David J. van Westerloo, Tom van der Poll, Willem A. van Gool, Diederik van de Beek
Publikováno v:
Cells, Vol 10, Iss 2, p 279 (2021)
Systemic infection is an important risk factor for the development cognitive impairment and neurodegeneration in older people. Animal experiments show that systemic challenges with live bacteria cause a neuro-inflammatory response, but the effect of
Externí odkaz:
https://doaj.org/article/f35ea60cceef4810827047b0630fb17a
Autor:
Inge C. M. Hoogland, Dunja Westhoff, Joo-Yeon Engelen-Lee, Jeroen Melief, Mercedes Valls Serón, Judith H. M. P. Houben-Weerts, Inge Huitinga, David J. van Westerloo, Tom van der Poll, Willem A. van Gool, Diederik van de Beek
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Background: Microglial activation after systemic infection has been suggested to mediate sepsis-associated delirium. A systematic review of animal studies suggested distinct differences between microglial activation after systemic challenge with live
Externí odkaz:
https://doaj.org/article/91a8d9dfa4fe468c8723a19ba8fe8c93
Severe, Persistent and Fatal Delirium in Psychogeriatric Patients Admitted to a Psychiatric Hospital
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 5, Iss 2, Pp 253-264 (2015)
Background/Aims: Although delirium is generally regarded as a transient syndrome, persistence of delirium in patients with cognitive impairment - even with fatal outcome - has been reported as well. This study aims to describe the clinical features a
Externí odkaz:
https://doaj.org/article/b836de5e3e174d54834604404be0ea52
Autor:
Hans Wouters, Bregje Appels, Jos Van Campen, Robert Lindeboom, Maarten Buiter, Aeilko H. Zwinderman, Willem A. van Gool, Ben Schmand
Publikováno v:
Behavioural Neurology, Vol 23, Iss 4, Pp 181-183 (2010)
Externí odkaz:
https://doaj.org/article/543630f4182842ba8bd485dd2edcebad
Autor:
Chantal J. Slor, Joost Witlox, Dimitrios Adamis, David J. Meagher, Tjeerd van der Ploeg, Rene W. M. M. Jansen, Mireille F. M. van Stijn, Alexander P. J. Houdijk, Willem A. van Gool, Piet Eikelenboom, Jos F. M. de Jonghe
Publikováno v:
Current Gerontology and Geriatrics Research, Vol 2013 (2013)
Background. Features that may allow early identification of patients at risk of prolonged delirium, and therefore of poorer outcomes, are not well understood. The aim of this study was to determine if preoperative delirium risk factors and delirium s
Externí odkaz:
https://doaj.org/article/7d638c4f20b14dc992080e1ceef9bb7b