Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Willem A. Dik"'
Autor:
Ikhwanuliman Putera, Benjamin Schrijver, P. Martijn Kolijn, Astrid C. van Stigt, Josianne C. E. M. ten Berge, Hanna IJspeert, Nicole M. A. Nagtzaam, Sigrid M. A. Swagemakers, Jan A. M. van Laar, Rupesh Agrawal, Saskia M. Rombach, P. Martin van Hagen, Rina La Distia Nora, Willem A. Dik
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Sarcoidosis and tuberculosis (TB) are two granulomatous diseases that often share overlapping clinical features, including uveitis. We measured 368 inflammation-related proteins in serum in both diseases, with and without uveitis from two di
Externí odkaz:
https://doaj.org/article/b0b00741299f4ad784a9dd558f407960
Autor:
Gijsbert J. Hötte, Maaike de Bie, Ronald O.B. de Keizer, P. Martijn Kolijn, Roosmarijn C. Drexhage, Sharon Veenbergen, Marjan A. Versnel, P. Martin van Hagen, Dion Paridaens, Willem A. Dik
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundFor the selective detection of thyroid-stimulating hormone receptor antibodies with stimulating properties (thyroid-stimulating immunoglobulins; TSI), a novel and rapid bioassay (Turbo TSI) has been introduced. We evaluate the clinical perf
Externí odkaz:
https://doaj.org/article/b885507448394a0dab78dc9868995ab0
Autor:
Benjamin Schrijver, Jens Göpfert, Rina La Distia Nora, Ikhwanuliman Putera, Nicole M.A.N. Nagtzaam, Marja A.W. Smits te Nijenhuis, Angelique L.C.T. van Rijswijk, Josianne C.E.M. ten Berge, Jan A.M. van Laar, P. Martin van Hagen, Willem A. Dik
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37103- (2024)
Objectives: In this study, we measured serum interferon (IFN) levels and activity in patients with sarcoidosis and tuberculosis (TB) with and without uveitis. We aimed to understand the role of IFN in the pathophysiology of both conditions and explor
Externí odkaz:
https://doaj.org/article/0ddcaff611204b618990b61e43e75b0c
Autor:
Sopita Visamol, Tanapat Palaga, Preamjit Saonanon, Vannakorn Pruksakorn, Nattiya Hirankarn, P. Martin van Hagen, Willem A. Dik, Sita Virakul
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Graves’ ophthalmopathy (GO) is an extra-thyroidal complication of Graves’ disease which can lead to vision loss in severe cases. Currently, treatments of GO are not sufficiently effective, so novel therapeutic strategies are needed. As p
Externí odkaz:
https://doaj.org/article/8dd7fca722344457ab37162a3d76d16f
Autor:
Rute M.S.M. Pedrosa, Johan M. Kros, Benjamin Schrijver, Cor Berrevoets, Rute B. Marques, Casper C.H.J. van Eijck, Reno Debets, PieterJ.M. Leenen, Willem A. Dik, DanaA.M. Mustafa
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e36598- (2024)
The appearance of brain metastasis is the most serious complication of breast cancer with mostly fatal outcomes. To reach the brain, tumor cells need to pass the blood-brain barrier (BBB). The molecular mechanisms underlying penetration of the BBB ar
Externí odkaz:
https://doaj.org/article/91b48a283cba4dc88e4fa1450d84f079
Bioinformatic meta-analysis reveals novel differentially expressed genes and pathways in sarcoidosis
Autor:
Rogier T. A. van Wijck, Hari S. Sharma, Sigrid M. A. Swagemakers, Willem A. Dik, Hanna IJspeert, Virgil A. S. H. Dalm, Paul L. A. van Daele, P. Martin van Hagen, Peter J. van der Spek
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionSarcoidosis is a multi-system inflammatory disease of unknown origin with heterogeneous clinical manifestations varying from a single organ non-caseating granuloma site to chronic systemic inflammation and fibrosis. Gene expression studie
Externí odkaz:
https://doaj.org/article/f8a6d8e6b3d74c478ef8b365b23c0637
Autor:
Gijsbert J. Hötte, P. Martijn Kolijn, Maaike de Bie, Ronald O. B. de Keizer, Marco Medici, Kim van der Weerd, P. Martin van Hagen, Dion Paridaens, Willem A. Dik
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThyroid stimulating immunoglobulins (TSI) play a central role in the pathogenesis of Graves’ orbitopathy (GO), while soluble interleukin-2 receptor (sIL-2R) is a marker for T-cell activity. We investigated TSI and sIL-2R levels in relatio
Externí odkaz:
https://doaj.org/article/c24e1427c5c140548ce1631ce50c68a4
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22468- (2023)
Background: Graves’ disease (GD) is caused by the production of TSH-receptor (TSHR) stimulating auto-antibodies. Over the years various TSHR-antibody (TRAb) detection assays have been developed. Most clinical laboratories use competitive TSH-bindin
Externí odkaz:
https://doaj.org/article/f0ea85efbe11468d851be8dd3a129ade
Autor:
Thomas J. P. Mangnus, Maaike Dirckx, Krishna D. Bharwani, Sara J. Baart, Theodora A. M. Siepman, Ken Redekop, Willem A. Dik, Cecile C. de Vos, Frank J. P. M. Huygen
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Complex regional pain syndrome (CRPS) is a chronic pain condition of an extremity. While achieving pain relief in CRPS is challenging, esketamine infusions can accomplish pain relief for several weeks post-infusion in a subgroup o
Externí odkaz:
https://doaj.org/article/262a96d8ef984b4eb97e07f5d3605abb
Autor:
Zhengzheng Zhang, Naama Karu, Alida Kindt, Madhulika Singh, Lieke Lamont, Adriaan J. van Gammeren, Anton A. M. Ermens, Amy C. Harms, Lutzen Portengen, Roel C. H. Vermeulen, Willem A. Dik, Anton W. Langerak, Vincent H. J. van der Velden, Thomas Hankemeier
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 296 (2024)
The severity of COVID-19 is linked to an imbalanced immune response. The dysregulated metabolism of small molecules and bioactive lipids has also been associated with disease severity. To promote understanding of the disease biochemistry and provide
Externí odkaz:
https://doaj.org/article/0adcf97b6f124302ab3467c687420a55