Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Willem, van Eden"'
Autor:
Jacob M van Laar, Anna de Goede, Gerty Schreibelt, Arie Jan Stoppelenburg, I Jolanda M de Vries, Paco Welsing, Bouke Koeneman, Evert-Jan Breman, Laureen Lammers, Tjitske Duiveman-de Boer, Willem van Eden, Paul Leufkens, Femke Broere
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction In rheumatoid arthritis (RA), immunosuppressive therapies may achieve symptomatic relief, but do not induce long-term, drug-free remission. Meanwhile, the lifelong use of immunosuppressive drugs confers increased risk for malignancy and
Externí odkaz:
https://doaj.org/article/048d163ecbc2444592ca57a8e33b4efc
Autor:
Qingkang Lyu, Edwin J A Veldhuizen, Irene S Ludwig, Victor P M G Rutten, Willem van Eden, Alice J A M Sijts, Femke Broere
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0292757 (2023)
Macrophages can reversibly polarize into multiple functional subsets depending on their micro-environment. Identification and understanding the functionality of these subsets is relevant for the study of immune‑related diseases. However, knowledge
Externí odkaz:
https://doaj.org/article/55841ebcdbeb4b8caad922416e3ff8cd
Autor:
Robin H. G. A. van den Biggelaar, Larissa van der Maas, Hugo D. Meiring, Jeroen L. A. Pennings, Willem van Eden, Victor P. M. G. Rutten, Christine A. Jansen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Inactivated poultry vaccines are subject to routine potency testing for batch release, requiring large numbers of animals. The replacement of in vivo tests for cell-based alternatives can be facilitated by the identification of biomarkers fo
Externí odkaz:
https://doaj.org/article/14a48ada534443fc9c1e168d1b014e78
Autor:
Willem van Eden
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 2, Pp 228-232 (2020)
Biologicals, e.g. TNF inhibitors, have improved dramatically the efficacy of medical interventions in autoimmune diseases, such as in rheumatoid arthritis (RA). However, although progressive inflammation can be halted in this way, no drug-free remiss
Externí odkaz:
https://doaj.org/article/3701e951694e4688bb8bad14a69cde3f
Autor:
Rachel Spiering, Manon A. A. Jansen, Matthew J. Wood, Anshorulloh A. Fath, Oliver Eltherington, Amy E. Anderson, Arthur G. Pratt, Willem van Eden, John D. Isaacs, Femke Broere, Catharien M. U. Hilkens
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Autologous tolerogenic dendritic cells (tolDC) are a promising therapeutic strategy for inflammatory arthritis (IA) as they can regulate autoantigen-specific T cell responses. Here, we investigated two outstanding priorities for c
Externí odkaz:
https://doaj.org/article/755e2b1899d548a39883bf1a0343da09
Autor:
Josep Bassaganya-Riera, Elliot M. Berry, Ellen E. Blaak, Barbara Burlingame, Johannes le Coutre, Willem van Eden, Ahmed El-Sohemy, J. Bruce German, Dietrich Knorr, Christophe Lacroix, Maurizio Muscaritoli, David C. Nieman, Michael Rychlik, Andrew Scholey, Mauro Serafini
Publikováno v:
Frontiers in Nutrition, Vol 7 (2021)
Five years ago, with the editorial board of Frontiers in Nutrition, we took a leap of faith to outline the Goals for Nutrition Science – the way we see it (1). Now, in 2020, we can put ourselves to the test and take a look back. Without a doubt we
Externí odkaz:
https://doaj.org/article/813c3f80743a43aa823a59c4a8824bad
Autor:
Robin H. G. A. van den Biggelaar, Ger J. A. Arkesteijn, Victor P. M. G. Rutten, Willem van Eden, Christine A. Jansen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Research in chickens has been fundamental for the discovery of basic aspects of the immune system and has led to an interest in the in-depth characterization of avian immune cell types including dendritic cells (DCs). The in vitro generation and expa
Externí odkaz:
https://doaj.org/article/ff3e5fb454704d73a6613923e6a3e9fb
Publikováno v:
Frontiers in Nutrition, Vol 7 (2020)
Externí odkaz:
https://doaj.org/article/66defaef726f44509422a489b6eddb1e
Autor:
Anne Marit de Groot, Kaushik Thanki, Monique Gangloff, Emily Falkenberg, Xianghui Zeng, Djai C.J. van Bijnen, Willem van Eden, Henrik Franzyk, Hanne M. Nielsen, Femke Broere, Nick J. Gay, Camilla Foged, Alice J.A.M. Sijts
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 159-169 (2018)
Therapeutics based on small interfering RNA (siRNA) have promising potential as antiviral and anti-inflammatory agents. To deliver siRNA across cell membranes to reach the RNAi pathway in the cytosol of target cells, non-viral nanoparticulate deliver
Externí odkaz:
https://doaj.org/article/8b2e828dc91a4199a7135eccfe8c545c
Autor:
Manon A. A. Jansen, Rachel Spiering, Irene S. Ludwig, Willem van Eden, Catharien M. U. Hilkens, Femke Broere
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Tolerogenic dendritic cells (tolDCs) are a promising treatment modality for diseases caused by a breach in immune tolerance, such as rheumatoid arthritis. Current medication for these diseases is directed toward symptom suppression but no real cure i
Externí odkaz:
https://doaj.org/article/cfc8baf47ce4400e9b5bc2d06f8fdd6a