Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Willcyn Tang"'
Autor:
Willcyn Tang, John Thundyil, Grace Gui Yin Lim, Teddy J W Tng, Sean Qing Zhang Yeow, Aditya Nair, Chou Chai, Tso-Pang Yao, Kah-Leong Lim
Publikováno v:
Human Molecular Genetics. 32:1466-1482
Abnormal lipid homeostasis has been observed in the brain of Parkinson's disease (PD) patients and experimental models, although the mechanism underlying this phenomenon is unclear. Notably, previous studies have reported that the PD-linked protein P
Lithium is a mood stabilizer broadly used to prevent and treat symptoms of mania and depression in people with bipolar disorder (BD). Little is known, however, about its mode of action. Here, we analyzed the impact of lithium on synaptic vesicle (SV)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb37be2df5a4dae9ee3b9ab02e8b4b3
https://doi.org/10.21203/rs.3.rs-1805872/v1
https://doi.org/10.21203/rs.3.rs-1805872/v1
Autor:
Adrian Röllin, Jagadish Sankaran, Thorsten Wohland, Xue Wen Ng, Harikrushnan Balasubramanian, Willcyn Tang
Super-resolution microscopy and single molecule fluorescence spectroscopy require mutually exclusive experimental strategies optimizing either time or spatial resolution. To achieve both, we implement a GPU-supported, camera-based measurement strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9aa0079c80f78faa41918c9af615a4b
Autor:
Loo Chin Wong, Bo Lu, Jervis Vermal Thevathasan, Lynette Lim, Fang Ji, Willcyn Tang, Kenrick An Fu Yap, Marc Fivaz, George J. Augustine, Shou Yu Poon, James J. Mancuso, Gisela Garcia-Alvarez, Kia Wee Tan
Publikováno v:
Molecular Biology of the Cell
STIMs (STIM1 and STIM2 in mammals) are transmembrane proteins that reside in the endoplasmic reticulum and regulate store-operated Ca2+ entry. STIM2 mediates cAMP/PKA-dependent phosphorylation of the AMPA receptor subunit GluA1 in excitatory neurons.
Autor:
Jervis Vermal Thevathasan, Willcyn Tang, Qingshu Lin, Kozo Kaibuchi, Tuck Wah Soong, Marc Fivaz, Kim Buay Lim, Keisuke Kuroda, Marcel Bilger
Publikováno v:
Frontiers in Synaptic Neuroscience
Lesions and mutations of the DISC1 (Disrupted-in-schizophrenia-1) gene have been linked to major depression, schizophrenia, bipolar disorder and autism, but the influence of DISC1 on synaptic transmission remains poorly understood. Using two independ