Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Willard J, Costain"'
Autor:
Caroline, Sodja, Deborah, Callaghan, Arsalan S, Haqqani, Danica B, Stanimirovic, Willard J, Costain, Anna, Jezierski
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2549
Automated high-throughput immunoassays are emerging as reliable analytic techniques for the quantitative detection of proteins from a variety of sample types. Herein, we describe a method using the Protein Simple Wes capillary-based automated immunoa
Autor:
Willard J. Costain, Salma Alasmar, Umberto Banderali, Maria Ribecco-Lutkiewicz, Caroline Sodja, Marzia Martina, Slavisa Corluka, Amy Aylsworth, Anna Jezierski, Ewa Baumann, Joseph S. Tauskela
Publikováno v:
Stem cell reviews and reports. 18(1)
Human induced pluripotent stem cell (iPSC)-derived neurons are of interest for studying neurological disease mechanisms, developing potential therapies and deepening our understanding of the human nervous system. However, compared to an extensive his
Publikováno v:
Histology and histopathology. 34(5)
The esophagus is a muscular tube which transports swallowed content from the oral cavity and the pharynx to the stomach. Early in mouse development, an entire layer of the esophagus, the muscularis externa, consists of differentiated smooth muscle ce
Autor:
Carol Ann Lirette, Jenna Day, Willard J. Costain, Linda J. Johnston, Robert Bittman, Young Ah Kim
Publikováno v:
Chemistry and Physics of Lipids. 194:117-124
Caged ceramide analogues (C6-, C16-, C18-, C22- and C24-Cer) have been prepared by introducing a hydrophilic coumarin-based cage bearing a short polyethylene glycol (PEG) chain. (6-Bromo-7-mTEGylated-coumarin-4-yl)methyl (Btc) caged ceramide showed e
Autor:
Julie Haukenfrers, Caroline Sodja, Fahar Merchant, Mahmud Bani-Yaghoub, Willard J. Costain, Maria Ribecco-Lutkiewicz
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 92:1001-1011
S-nitrosoglutathione (GSNO) is an endogenously produced S-nitrosylating compound that controls the function of various proteins. While a number of rodent cell lines have been used to study GSNO-induced apoptosis, the mechanisms of action remain to be
Autor:
Melissa Hewitt, Amy Aylsworth, Tanya Comas, Vincent Marleau, Yanouchka Rouleau, Evelyn C. Soo, Willard J. Costain, Ingrid Rasquinha, Joseph S. Tauskela
Publikováno v:
European journal of pharmacology. 823
Synthetic cannabinoids are marketed as legal alternatives to Δ9-THC, and are a growing worldwide concern as these drugs are associated with severe adverse effects. Unfortunately, insufficient information regarding the physiological and pharmacologic
Autor:
Willard J. Costain, Marzia Martina, Melissa Hewitt, Amy Aylsworth, Tanya Comas, Xigeng Zhao, Joseph S. Tauskela
Publikováno v:
European journal of pharmacology. 786
Activation of cannabinoid receptor 1 (CB1) inhibits synaptic transmission in hippocampal neurons. The goal of this study was to evaluate the ability of benchmark and emerging synthetic cannabinoids to suppress neuronal activity in vitro using two com
Publikováno v:
Histology and histopathology. 31(7)
The current paper is a continuation of our work most recently described in Kablar, 2011. Here, we show lists of up- and down-regulated genes obtained by a cDNA microarray analysis that compared developing mouse MyoD-/- limb musculature (MyoD-dependen
Autor:
Nadia L. Caram-Salas, Willard J. Costain, Carl I. Webster, Eric Brunette, Alvaro Yogi, Danica Stanimirovic, George Thom, Lee Brown, Kerry Rennie, Arsalan S. Haqqani
Receptor mediated transcytosis harnessing the cellular uptake and transport of natural ligands across the blood-brain barrier (BBB) has been identified as a means for antibody delivery to the CNS. In this study, we characterized bispecific antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9154178617133eed45019af6eebcbfd
https://doi.org/10.1096/fj.201500078
https://doi.org/10.1096/fj.201500078