Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Willa D, Brenowitz"'
Autor:
Willa D. Brenowitz, Yang Xiang, Claire T. McEvoy, Cui Yang, Kristine Yaffe, Wei-Dong Le, Yue Leng, Yuan-Yuan Ji
Publikováno v:
Chinese Medical Journal, Vol 134, Iss 18, Pp 2150-2159 (2021)
Abstract. Alzheimer disease (AD) is the most common type of dementia characterized by the progressive cognitive and social decline. Clinical drug targets have heavily focused on the amyloid hypothesis, with amyloid beta (Aβ), and tau proteins as key
Externí odkaz:
https://doaj.org/article/376c46cda8294ba7a2f49e00a951d4e5
Autor:
Sarah F. Ackley, Eleanor Hayes-Larson, Willa D. Brenowitz, Kaitlin Swinnerton, Dan Mungas, Evan Fletcher, Baljeet Singh, Rachel A. Whitmer, Charles DeCarli, M. Maria Glymour
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102713- (2021)
Background: Amyloid β (Aβ) is thought to initiate a cascade of pathology culminating in Alzheimer’s disease-related cognitive decline. Aβ accumulation in brain tissues may begin one to two decades prior to clinical diagnosis of Alzheimer’s dis
Externí odkaz:
https://doaj.org/article/c7a1f022e308495dad77034c563cbdfc
Autor:
Willa D. Brenowitz, Myriam Fornage, Lenore J. Launer, Mohamad Habes, Christos Davatzikos, Kristine Yaffe
Publikováno v:
Annals of Neurology. 93:629-634
We examined associations of an AD genetic risk score (AD-GRS) and midlife cognitive and neuroimaging outcomes in 1,252 middle-aged participants (311 with brain MRI). A higher AD-GRS based on 25 previously identified loci (excluding APOE) was associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c6d7ea8aa10cfc6fcf9d3dbb75a916
https://doi.org/10.1002/ana.26569
https://doi.org/10.1002/ana.26569
Autor:
Fang Han, Tyler Bonnett, Willa D Brenowitz, Merilee A Teylan, Lilah M Besser, Yen-Chi Chen, Gary Chan, Ke-Gang Cao, Ying Gao, Xiao-Hua Zhou
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227924 (2020)
IntroductionPrevious studies have provided equivocal evidence of antidepressant use on subsequent cognitive impairment; this could be due to inconsistent modeling approaches. Our goals are methodological and clinical. We evaluate the impact of statis
Externí odkaz:
https://doaj.org/article/830a0b5dd5c8420f830bafdda6d656eb
Autor:
Phillip H. Hwang, W.T. Longstreth Jr, Willa D. Brenowitz, Stephen M. Thielke, Oscar L. Lopez, Courtney E. Francis, Steven T. DeKosky, Annette L. Fitzpatrick
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Hearing and vision loss are independently associated with dementia, but the impact of dual sensory impairment (DSI) on dementia risk is not well understood. Methods Self‐reported measures of hearing and vision were taken from
Externí odkaz:
https://doaj.org/article/ab123c2739ab423a9ac5bc6854d35e9e
Autor:
Nicole M. Armstrong, Camila Vieira Ligo Teixeira, Colby Gendron, Willa D. Brenowitz, Frank R. Lin, Bonnelin Swenor, Jennifer A. Deal, Eleanor M. Simonsick, Richard N. Jones
Publikováno v:
J Am Geriatr Soc
BACKGROUND: There is a dearth of studies examining the associations of objectively measured dual sensory impairment (DSI) with incident mobility and activities of daily life (ADL) difficulty longitudinally. METHODS: Cox proportional hazards models we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b60e37d405ef481aea8ad96b4b87db7
https://doi.org/10.1111/jgs.17764
https://doi.org/10.1111/jgs.17764
Autor:
Peter Buto, Kaitlin N. Swinnerton, Renaud La Joie, Scott C Zimmerman, M. Maria Glymour, Sarah F Ackley, Willa D Brenowitz
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b625a2784bc36ecdf6bd09452950a03c
https://doi.org/10.1002/alz.066409
https://doi.org/10.1002/alz.066409
Autor:
Willa D. Brenowitz, Kristine Yaffe
Publikováno v:
Nature reviews. Neurology. 18(12)
Recent high-profile failures of Alzheimer disease treatments at the clinical trial stage have led to renewed efforts to identify and test novel interventions for Alzheimer disease and related dementias (ADRD). In this Perspective, we highlight the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ff7482e2d2f23cb8700e504815592c
https://pubmed.ncbi.nlm.nih.gov/36316487
https://pubmed.ncbi.nlm.nih.gov/36316487
Autor:
Benjamin K.J. Tan, Tien Y Wong, Alfred Tau Liang Gan, Preeti Gupta, Varshini Varadaraj, Greta Rait, Christopher Chen, Felipe A. Medeiros, Sigrid Mueller-Schotte, Carlos A. Reyes-Ortiz, Willa D. Brenowitz, Virginie Nael, Jacobijn Gussekloo, Kaavya Narasimhalu, Allen T C Lee, Ryan E. K. Man, Ecosse L. Lamoureux, Tai Anh Vu, Yih Chung Tham, Stella Trompet, Bonnielin K. Swenor, Eva K Fenwick, Ching-Yu Cheng, Kam Chun Ho, Joan M. O'Brien
Publikováno v:
Ophthalmology. 128:981-992
Topic Visual impairment (VI) and cognitive impairment (CIM) are prevalent age-related conditions that impose substantial burden on the society. Findings on the hypothesized bidirectional association of VI and CIM remains equivocal. Hence, we conducte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0dfc91a2381af4801e5101a32c96076
https://doi.org/10.1016/j.ophtha.2020.12.010
https://doi.org/10.1016/j.ophtha.2020.12.010
Autor:
Monica Ospina-Romero, Willa D. Brenowitz, M. Maria Glymour, Ashly Westrick, Rebecca E. Graff, Eleanor Hayes-Larson, Elizabeth Rose Mayeda, Sarah F. Ackley, Lindsay C. Kobayashi
Publikováno v:
Journal of Geriatric Oncology. 14:101530
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea06e7d03984cbe1bebff741c6573f0a
https://doi.org/10.1016/j.jgo.2023.101530
https://doi.org/10.1016/j.jgo.2023.101530