Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Willa A Hsueh"'
Autor:
Artak Labadzhyan, Jinrui Cui, Miklós Péterfy, Xiuqing Guo, Yii-Der I Chen, Willa A Hsueh, Jerome I Rotter, Mark O Goodarzi
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166263 (2016)
Reduction in insulin clearance plays an important role in the compensatory response to insulin resistance. Given the importance of this trait to the pathogenesis of diabetes, a deeper understanding of its regulation is warranted. Our goal was to iden
Externí odkaz:
https://doaj.org/article/34ae990c24314f3593e31ad96437a02c
Autor:
Dharti Shantaram, Rebecca Hoyd, Alecia M. Blaszczak, Linda Antwi, Anahita Jalilvand, Valerie P. Wright, Joey Liu, Alan J. Smith, David Bradley, William Lafuse, YunZhou Liu, Nyelia F. Williams, Owen Snyder, Caroline Wheeler, Bradley Needleman, Stacy Brethauer, Sabrena Noria, David Renton, Kyle A. Perry, Prabha Nagareddy, Daniel Wozniak, Sahil Mahajan, Pranav S. J. B. Rana, Maciej Pietrzak, Larry S. Schlesinger, Daniel J. Spakowicz, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Neutrophils are increasingly implicated in chronic inflammation and metabolic disorders. Here, we show that visceral adipose tissue (VAT) from individuals with obesity contains more neutrophils than in those without obesity and is associated
Externí odkaz:
https://doaj.org/article/9193f2df0d714844a1ba35b032ffb441
Autor:
Charlene T Lichtash, Jinrui Cui, Xiuqing Guo, Yii-Der I Chen, Willa A Hsueh, Jerome I Rotter, Mark O Goodarzi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65954 (2013)
The worldwide prevalence of obesity mandates a widely accessible tool to categorize adiposity that can best predict associated health risks. The body adiposity index (BAI) was designed as a single equation to predict body adiposity in pooled analysis
Externí odkaz:
https://doaj.org/article/7e1df8a8bc7944aea648263a4b384282
Autor:
Marcelo Vizoná Liberato, Alessandro S Nascimento, Steven D Ayers, Jean Z Lin, Aleksandra Cvoro, Rodrigo L Silveira, Leandro Martínez, Paulo C T Souza, Daniel Saidemberg, Tuo Deng, Angela Angelica Amato, Marie Togashi, Willa A Hsueh, Kevin Phillips, Mário Sérgio Palma, Francisco A R Neves, Munir S Skaf, Paul Webb, Igor Polikarpov
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36297 (2012)
Thiazolidinediones (TZDs) act through peroxisome proliferator activated receptor (PPAR) γ to increase insulin sensitivity in type 2 diabetes (T2DM), but deleterious effects of these ligands mean that selective modulators with improved clinical profi
Externí odkaz:
https://doaj.org/article/a609d0a8ff1a460d97ac8adf04ce50fa
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13748 (2010)
Gene network information has been used to improve gene selection in microarray-based studies by selecting marker genes based both on their expression and the coordinate expression of genes within their gene network under a given condition. Here we pr
Externí odkaz:
https://doaj.org/article/f21055bab854499b973e95fc9a6d94f9
Autor:
Xiyan Liao, Qin Zeng, Limin Xie, Haowei Zhang, Wanyu Hu, Liuling Xiao, Hui Zhou, Fanqi Wang, Wanqin Xie, Jianfeng Song, Xiaoxiao Sun, Dandan Wang, Yujin Ding, Yayi Jiao, Wuqian Mai, Wufuer Aini, Xiaoyan Hui, Wei Liu, Willa A. Hsueh, Tuo Deng
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113963- (2024)
Summary: T cell infiltration into white adipose tissue (WAT) drives obesity-induced adipose inflammation, but the mechanisms of obesity-induced T cell infiltration into WAT remain unclear. Our single-cell RNA sequencing reveals a significant impact o
Externí odkaz:
https://doaj.org/article/57fce9b83d8041aeb1c2f03a6252fef2
Autor:
Joshua J. Joseph, Bjorn Kluwe, Songzhu Zhao, David Kline, Divya Nedungadi, Guy Brock, Willa A. Hsueh, Sherita H. Golden
Publikováno v:
Endocrine and Metabolic Science, Vol 11, Iss , Pp 100128- (2023)
Introduction: African Americans (AAs) have the highest prevalence of hypertension among United States racial/ethnic groups. Regulators of blood pressure, such as aldosterone and endothelin-1, impact glucose regulation. The relationship between these
Externí odkaz:
https://doaj.org/article/275e44f64e8c4d569c95f28adc97072a
Autor:
Xin He, Andrea Cardona, Aaron O'Brien, Matthew C Bernier, Arpad Somogyi, Vicki H Wysocki, Suzanne Smart, Giuseppe Ambrosio, Willa Ann Hsueh, Subha V Raman
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 7, Iss 1 (2019)
Introduction Type 2 diabetes mellitus (T2D) confers high atherosclerotic cardiovascular disease (ASCVD) risk. The metabolite trimethylamine N-oxide (TMAO) derived via gut flora has been linked to excess ASCVD.Research design and methods We analyzed d
Externí odkaz:
https://doaj.org/article/404c52bf2ae34fd28c9740273a4cd472
Autor:
Joshua J. Joseph, Susan Langan, Joseph Lunyera, Bjorn Kluwe, Amaris Williams, Haiying Chen, Michael C. Sachs, Kristin G. Hairston, Alain G. Bertoni, Willa A. Hsueh, Sherita H. Golden
Publikováno v:
Nutrition & Diabetes. 12
BackgroundIncident diabetes risk is inversely proportional to 25-hydroxyvitamin D [25(OH)D] levels among non-Hispanic white but is unclear among African American (AA) populations. Serum 25(OH)D2 may be an important component of total 25(OH)D among AA
Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL
Autor:
Esteban J. Parra, Craig L. Hanis, Lisa Sanchez-Johnsen, Kristin L. Young, Misa Graff, Yujie Wang, Adán Valladares, Lauren E. Petty, Yii-Der Ida Chen, Xiuqing Guo, Mark O. Goodarzi, Miguel Cruz, Kari E. North, Anny H. Xiang, Leslie J. Raffel, Matthew A. Allison, Tamar Sofer, Yann C. Klimentidis, Shelly Ann Love, Anne E. Justice, Stephanie M. Gogarten, Fernando Pires Hartwig, Thomas A. Buchanan, Jennifer E. Below, Jingyi Tan, Jie Yao, Jerome I. Rotter, Willa A. Hsueh, Eli Ipp, Walter Palmas, Kent D. Taylor, Heather M. Highland, Carmen R. Isasi
Publikováno v:
Human Molecular Genetics
Author(s): Justice, Anne E; Young, Kristin; Gogarten, Stephanie M; Sofer, Tamar; Graff, Misa; Love, Shelly Ann M; Wang, Yujie; Klimentidis, Yann C; Cruz, Miguel; Guo, Xiuqing; Hartwig, Fernando; Petty, Lauren; Yao, Jie; Allison, Matthew A; Below, Jen