Zobrazeno 1 - 10
of 472
pro vyhledávání: '"Willa A Hsueh"'
Autor:
Dharti Shantaram, Rebecca Hoyd, Alecia M. Blaszczak, Linda Antwi, Anahita Jalilvand, Valerie P. Wright, Joey Liu, Alan J. Smith, David Bradley, William Lafuse, YunZhou Liu, Nyelia F. Williams, Owen Snyder, Caroline Wheeler, Bradley Needleman, Stacy Brethauer, Sabrena Noria, David Renton, Kyle A. Perry, Prabha Nagareddy, Daniel Wozniak, Sahil Mahajan, Pranav S. J. B. Rana, Maciej Pietrzak, Larry S. Schlesinger, Daniel J. Spakowicz, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Neutrophils are increasingly implicated in chronic inflammation and metabolic disorders. Here, we show that visceral adipose tissue (VAT) from individuals with obesity contains more neutrophils than in those without obesity and is associated
Externí odkaz:
https://doaj.org/article/9193f2df0d714844a1ba35b032ffb441
Autor:
Xiyan Liao, Qin Zeng, Limin Xie, Haowei Zhang, Wanyu Hu, Liuling Xiao, Hui Zhou, Fanqi Wang, Wanqin Xie, Jianfeng Song, Xiaoxiao Sun, Dandan Wang, Yujin Ding, Yayi Jiao, Wuqian Mai, Wufuer Aini, Xiaoyan Hui, Wei Liu, Willa A. Hsueh, Tuo Deng
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113963- (2024)
Summary: T cell infiltration into white adipose tissue (WAT) drives obesity-induced adipose inflammation, but the mechanisms of obesity-induced T cell infiltration into WAT remain unclear. Our single-cell RNA sequencing reveals a significant impact o
Externí odkaz:
https://doaj.org/article/57fce9b83d8041aeb1c2f03a6252fef2
Autor:
Joshua J. Joseph, Susan Langan, Joseph Lunyera, Bjorn Kluwe, Amaris Williams, Haiying Chen, Michael C. Sachs, Kristin G. Hairston, Alain G. Bertoni, Willa A. Hsueh, Sherita H. Golden
Publikováno v:
Nutrition & Diabetes, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Background Incident diabetes risk is inversely proportional to 25-hydroxyvitamin D [25(OH)D] levels among non-Hispanic white but is unclear among African American (AA) populations. Serum 25(OH)D2 may be an important component of total 25(OH)
Externí odkaz:
https://doaj.org/article/390e5611ace044cd81c7cd7ee4344b65
Autor:
David Bradley, Alan J. Smith, Alecia Blaszczak, Dharti Shantaram, Stephen M. Bergin, Anahita Jalilvand, Valerie Wright, Kathleen L. Wyne, Revati S. Dewal, Lisa A. Baer, Katherine R. Wright, Kristin I. Stanford, Bradley Needleman, Stacy Brethauer, Sabrena Noria, David Renton, Joshua J. Joseph, Amy Lovett-Racke, Joey Liu, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Murine models of obesity suggest that decreases in the adipose tissue regulatory T cell compartment may contribute to insulin resistance, but how this corresponds in the human clinical context is less well understood. Here the authors propose a role
Externí odkaz:
https://doaj.org/article/5cf60e1c6bd444d5a39e474ea1128c55
Autor:
Joshua J. Joseph, Bjorn Kluwe, Songzhu Zhao, David Kline, Divya Nedungadi, Guy Brock, Willa A. Hsueh, Sherita H. Golden
Publikováno v:
Endocrine and Metabolic Science, Vol 11, Iss , Pp 100128- (2023)
Introduction: African Americans (AAs) have the highest prevalence of hypertension among United States racial/ethnic groups. Regulators of blood pressure, such as aldosterone and endothelin-1, impact glucose regulation. The relationship between these
Externí odkaz:
https://doaj.org/article/275e44f64e8c4d569c95f28adc97072a
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/a0df6cf60c6f494998faedf71d6259fc
Autor:
Joshua J. Joseph, Bjorn Kluwe, Justin B. Echouffo‐Tcheugui, Songzhu Zhao, Guy Brock, David Kline, James B. Odei, Rita R. Kalyani, David P. Bradley, Willa A. Hsueh, Mario Sims, Sherita H. Golden
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)
Background The prognostic value of anthropometric, adipokine, and computed tomography measures of adiposity to predict diabetes in Black, specifically by normoglycemia versus prediabetes, remains incompletely understood. Methods and Results Among Bla
Externí odkaz:
https://doaj.org/article/361e82dc99314656bf329e3654d9b759
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The role of adipose tissue (AT) inflammation in obesity and its multiple related-complications is a rapidly expanding area of scientific interest. Within the last 30 years, the role of the adipocyte as an endocrine and immunologic cell has been progr
Externí odkaz:
https://doaj.org/article/0140dc6987484bafa598cd46b803f439
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Autor:
Tuo Deng, Joey Liu, Yanru Deng, Laurie Minze, Xiang Xiao, Valerie Wright, Richeng Yu, Xian C. Li, Alecia Blaszczak, Stephen Bergin, David DiSilvestro, Ryan Judd, David Bradley, Michael Caligiuri, Christopher J. Lyon, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Obesity is associated with inflammation in adipose tissue, characterized by a shift in local T cell subsets. Here the authors show that loss of MHCII expression on adipocytes increases levels of immunosuppressive regulatory T cells in adipose tissue,
Externí odkaz:
https://doaj.org/article/f06d437e5dce45deabca2a777dc8a491