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Autor:
Markku Laakso, Gromoslaw A. Smolen, Eric L. Allen, Abhishek K. Jha, Qi Wang, Luke L. Miller, Prashanth T. Bhaskar, Krushna C. Patra, Zebin Wang, Nissim Hay, R. Brooks Robey, Navdeep S. Chandel, Michelle Clasquin, William J. Muller, Will Wheaton
Publikováno v:
Cancer Cell. (2):213-228
SummaryAccelerated glucose metabolism is a common feature of cancer cells. Hexokinases catalyze the first committed step of glucose metabolism. Hexokinase 2 (HK2) is expressed at high level in cancer cells, but only in a limited number of normal adul