Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Will McDonough"'
Autor:
Abigail Boyd, Ileana V. Aragon, Justin Rich, Will McDonough, Marianna Oditt, Daniel Irelan, Edward Fiedler, Lina Abou Saleh, Wito Richter
Publikováno v:
Biology, Vol 10, Iss 12, p 1355 (2021)
Treatment with PAN-PDE4 inhibitors has been shown to produce hypothermia in multiple species. Given the growing body of evidence that links nausea and emesis to disturbances in thermoregulation in mammals, we explored PDE4 inhibitor-induced hypotherm
Externí odkaz:
https://doaj.org/article/68a9b275b8504172a7584ff248764bbd
Autor:
Daniel Irelan, Abigail Boyd, Edward Fiedler, Peter Lochmaier, Will McDonough, Ileana V. Aragon, Lyudmila Rachek, Lina Abou Saleh, Wito Richter
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3260
Volume 24
Issue 4
Pages: 3260
cAMP-phosphodiesterase 4 (PDE4) inhibitors are currently approved for the treatment of inflammatory diseases. There is interest in expanding the therapeutic application of PDE4 inhibitors to metabolic disorders, as their chronic application induces w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9ad739c068a74d6019a8c5f1824571
https://doi.org/10.3390/ijms24043260
https://doi.org/10.3390/ijms24043260
Autor:
Abigail Boyd, Ileana V. Aragon, Will McDonough, Wito Richter, Justin Rich, Anna Koloteva, Lina Abou Saleh
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502c9f289dfe829ccb084f4a52c1bd2b
https://doi.org/10.1096/fasebj.2021.35.s1.00153
https://doi.org/10.1096/fasebj.2021.35.s1.00153
Autor:
Will McDonough, Justin Rich, Ileana V. Aragon, Wito Richter, Lina Abou Saleh, Abigail Boyd, Anna Koloteva
Publikováno v:
Biochem Pharmacol
Despite major advances, there remains a need for novel anesthetic drugs or drug combinations with improved efficacy and safety profiles. Here, we show that inhibition of cAMP-phosphodiesterase 4 (PDE4), while not inducing anesthesia by itself, potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec796406741d1f0bb0cd20438b3854a
https://pubmed.ncbi.nlm.nih.gov/33609559
https://pubmed.ncbi.nlm.nih.gov/33609559
Autor:
Ileana V. Aragon, Wito Richter, Justin Rich, Lina Abou Saleh, Aris Richter, Will McDonough, Anna Koloteva, Abigail Boyd
Publikováno v:
Biochem Pharmacol
Inhibitors of Type 4 cAMP-phosphodiesterases (PDE4s) exert a number of promising therapeutic benefits, including potent anti-inflammatory, memory- and cognition-enhancing, metabolic, and antineoplastic effects. We report here that treatment with a nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dac0eb2b4e6de5f0a0dfe8799db8668
https://doi.org/10.1016/j.bcp.2020.114158
https://doi.org/10.1016/j.bcp.2020.114158
Autor:
Abigail Boyd, Ileana V. Aragon, Will McDonough, Lina Abou Saleh, Wadad Mneimneh, Wito Richter, Robert A. Barrington, Domenico Spadafora, Anna Koloteva
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b70ce3b5195f8af161b6156f7bae25
https://doi.org/10.1096/fasebj.2020.34.s1.05664
https://doi.org/10.1096/fasebj.2020.34.s1.05664
Autor:
Will McDonough, Abigail Boyd, Justin Rich, Ileana V. Aragon, Wito Richter, James M. Murphy, Anna Koloteva, Lina Abou Saleh
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee402bfcfb23e2f144b56347f693ffde
https://doi.org/10.1096/fasebj.2020.34.s1.05105
https://doi.org/10.1096/fasebj.2020.34.s1.05105
Autor:
Aris Richter, Lina Abou Saleh, Justin Rich, Anna Koloteva, Abigail Boyd, Will McDonough, Ileana V. Aragon, Wito Richter
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe1d233d13296b13c1f6672856cebd47
https://doi.org/10.1096/fasebj.2020.34.s1.04497
https://doi.org/10.1096/fasebj.2020.34.s1.04497