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pro vyhledávání: '"Will Lake"'
Autor:
Ryan A. Koppes, Will Lake, Abigail N. Koppes, Shashi K. Murthy, David T. Breault, Eric Stas, Sanjin Hosic
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: The intestinal epithelium contains specialized cells including enterocytes, goblet, Paneth, enteroendocrine, and stem cells. Impaired barrier integrity in Inflammatory Bowel Disease is characterized by elevated levels of pro-inflammator
Autor:
Will Lake, David T. Breault, Shashi K. Murthy, Adam J. Bindas, Marissa Puzan, Sanjin Hosic, Abigail N. Koppes, Fanny Zhou, Ryan A. Koppes, Jonathan R. Soucy
Publikováno v:
ACS Biomater Sci Eng
Microfluidic organs-on-chips aim to realize more biorelevant in vitro experiments compared to traditional two-dimensional (2D) static cell culture. Often such devices are fabricated via poly(dimethylsiloxane) (PDMS) soft lithography, which offers ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f36fe66e516f7de05fc890a6a4be037
https://europepmc.org/articles/PMC8290094/
https://europepmc.org/articles/PMC8290094/
Autor:
Shashi K. Murthy, Ryan A. Koppes, David T. Breault, Abigail N. Koppes, Sanjin Hosic, Marissa Puzan, Fanny Zhou, Will Lake
Here we report benchtop fabrication of multilayer thermoplastic organs-on-chips via laser cut and assembly of double sided adhesives. Biocompatibility was evaluated with Caco-2 cells and primary human intestinal organoids. Chips with Luer fluidic int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd6a3e8c02b5cec3cf737d7cf0dd78a