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pro vyhledávání: '"Will Laird"'
Autor:
Austin Stoner, Li Fu, LaShae Nicholson, Chao Zheng, Takuya Toyonaga, Joshua Spurrier, Will Laird, Zhengxin Cai, Stephen M. Strittmatter
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Progression of Alzheimer’s disease leads to synapse loss, neural network dysfunction and cognitive failure. Accumulation of protein aggregates and brain immune activation have triggering roles in synaptic failure but the neurona
Externí odkaz:
https://doaj.org/article/3623c85b0dce469790d861d7fd59b683
Autor:
Austin Stoner, Li Fu, LaShae Nicholson, Chao Zheng, Takuya Toyonaga, Joshua Spurrier, Will Laird, Zhengxin Cai, Stephen M. Strittmatter
BackgroundCellular prion protein (PrPC) is a high-affinity cell-surface receptor for Amyloid-β oligomers (Aßo). In certain overexpression models of Alzheimer’s Disease (AD), pharmacology and genetics demonstrate its essential role for synaptic pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10d0f08040ec898788ae47320e6d3f0
https://doi.org/10.1101/2023.02.15.528700
https://doi.org/10.1101/2023.02.15.528700