Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Will Goth"'
Autor:
Coinneach Mackenzie Dover, Will Goth, Christian Goodbrake, James W. Tunnell, Michael S. Sacks
Publikováno v:
Annals of Biomedical Engineering. 50:253-277
In the present study, we demonstrate that soft tissue fiber architectural maps captured using polarized spatial frequency domain imaging (pSFDI) can be utilized as an effective texture source for DIC-based planar surface strain analyses. Experimental
Autor:
Treshayla Brown, Aislinn Hurley, James W. Tunnell, Matthew C. Fox, Andrew C. Stier, Jason S. Reichenberg, Pengyu Ren, Will Goth, Mia K. Markey, Katherine R. Sebastian, Yao Zhang, Xu Feng, Fabiana C.P.S. Lopes
Publikováno v:
Journal of Biomedical Optics
Significance: Sub-diffuse optical properties may serve as useful cancer biomarkers, and wide-field heatmaps of these properties could aid physicians in identifying cancerous tissue. Sub-diffuse spatial frequency domain imaging (sd-SFDI) can reveal su
Autor:
Matthew C. Fox, Yao Zhang, Xu Feng, Mia K. Markey, Aislinn Hurley, Jason S. Reichenberg, Will Goth, James W. Tunnell, Katherine R. Sebastian, Andrew C. Stier, Fabiana C.P.S. Lopes
Publikováno v:
Molecular-Guided Surgery: Molecules, Devices, and Applications VII.
Analyzing Spatial Frequency Domain Images (SFDI) of tissue in the sub-diffuse domain can reveal optical properties (μs’, γ) of the tissue related to its microstructural composition and shows potential for use in image-guided cancer removal. Howev
Autor:
Andrew C. Stier, Mia K. Markey, Jason S. Reichenberg, Will Goth, Matthew C. Fox, Yao Zhang, James W. Tunnell, Fabiana C.P.S. Lopes, Katherine R. Sebastian
Publikováno v:
Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN).
We demonstrate a machine learning approach that renders real-time subdiffuse optical property (γ) maps from spatial frequency domain images, laying the foundation for use in surgical guidance.
Autor:
Michael S. Sacks, Janet Zoldan, Will Goth, Alicia C.B. Allen, Samuel Potter, James W. Tunnell
Publikováno v:
Ann Biomed Eng
Collagen fibers are the primary structural elements that define many soft-tissue structure and mechanical function relationships, so that quantification of collagen organization is essential to many disciplines. Current tissue-level collagen fiber im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ceeaad06e586761eb3146aac1b2a9e
https://europepmc.org/articles/PMC6456388/
https://europepmc.org/articles/PMC6456388/
Publikováno v:
SPIE Proceedings.
Polarized light is commonly used to detect optical anisotropies, such as birefringence, in tissues. This optical anisotropy is often attributed to underlying structural anisotropy in tissue, which may originate from regularly aligned collagen fibers.
Fibrous structures are an integral and dynamic feature of soft biological tissues that are directly related to the tissues’ condition and function. A greater understanding of mechanical tissue behavior can be gained through quantitative analyses of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af399360416f54a4ca312c033d00534c
https://europepmc.org/articles/PMC5537381/
https://europepmc.org/articles/PMC5537381/
Publikováno v:
SPIE Proceedings.
Our group previously introduced Polarized Spatial Frequency Domain Imaging (PSFDI), a wide-field, reflectance imaging technique which we used to empirically map fiber direction in porcine pulmonary heart valve leaflets (PHVL) without optical clearing
Publikováno v:
SPIE Proceedings.
Biocompatible Optical Needle Array (BONA) is showing to be a powerful tool complementing the novel antibacterial blue light therapy. BONA is able to deliver light to deeper skin tissue layers successfully as shown in experiments. In this study, we wi
Publikováno v:
Journal of biomedical optics. 19(10)
The sampling depth of light for diffuse reflectance spectroscopy is analyzed both experimentally and computationally. A Monte Carlo (MC) model was used to investigate the effect of optical properties and probe geometry on sampling depth. MC model est