Treatment of mild to moderate Graves' ophthalmopathy with sodium diclofenac: a pilot study

Autor: Walter Bloise, Lidia Yuri Mimura, Wilian Nicolau, Janete Moura

Publikováno v: Arquivos Brasileiros de Endocrinologia & Metabologia v.55 n.9 2011
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM

OBJECTIVE: To report the use of sodium diclofenac, an antagonist of PPAR-gamma and cyclooxigenase-2 (COX-2) inhibitor in the treatment of mild to moderate Graves' ophthalmopathy. SUBJECTS AND METHODS: Thirteen patients with clinical activity score (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9d322b9d169584d57c06b484d7b40d
https://doi.org/10.1590/s0004-27302011000900004

Growth Hormone Receptor Messenger Ribonucleic Acid in Normal and Pathologic Human Adrenocortical Tissues—An Analysis by Quantitative Polymerase Chain Reaction Technique1

Autor: Antonio Marmo Lucon, Chin Jia Lin, Isabel Guazzelli, Berenice B. Mendonca, Wilian Nicolau, Sandra M.F. Villares

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 82:2671-2676

GH receptor (GHR) has been reported to express in both normal rat and human adrenals. However, no study examined GHR expression in diseased human adrenal cortex. We quantitated, with RT-PCR, GHR messenger RNA (mRNA) in both normal and diseased human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79cb1eb7a5e4b1cacd10b1ac5c210f87
https://doi.org/10.1210/jcem.82.8.4159

Pulsatile Release and Circadian Rhythms of Thyrotropin and Prolactin in Children with Growth Hormone Deficiency

Autor: Luiz Roberto Salgado, Bernardo Liberman, Amilton Faria, William S. Evans, Bernardo Léo Wajchenberg, Mirta Knoepfelmacher, Sandra M.F. Villares, Wilian Nicolau

Publikováno v: Pediatric Research. 39:1006-1011

We have measured mean concentrations and have appraised the pulsatile nature of thyrotropin (TSH) and prolactin (PRL) release in children with classical GH deficiency (GHD; n = 4) and neurosecretory GH dysfunction (NSD; n = 4) and have compared the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c8de60b6a826281ada4633e620f346
https://doi.org/10.1203/00006450-199606000-00013

Lack of reduction in body fat after treatment with insulin-like growth factor-I in two children with growth hormone gene deletions

Autor: Berenice B. Mendonca, I J P Arnhold, Wilian Nicolau, Antonio C. Bianco, S. B. Oliveira, M G F Osorio, Alexandre J. F. Carrilho

Publikováno v: Journal of endocrinological investigation. 23(4)

Two patients with growth hormone (GH) gene deletions were treated with recombinant insulin-like growth factor-I (IGF-I) (80-240 (microg/kg/day) and the effects on bone mass and body composition were compared to administration of GH (0.075 U/kg/day) t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441525f625c4c717fb5247745be08066
https://pubmed.ncbi.nlm.nih.gov/10853714

Calcium and prolactin secretion in humans: effects of the channel blocker, verapamil, in the spontaneous and drug-induced hyperprolactinemia

Autor: A. C. Lerário, Mirta Knoepfelmacher, Wilian Nicolau, Bernardo Leo Wajchenberg, Bernardo Liberman, Sandra M.F. Villares, O. O. Germek

Publikováno v: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 26(10)

The effects of the intravenous administration of a calcium channel blocker, verapamil (0.0833 mg/min for 2-3 h after a 5 mg bolus) on prolactin (PRL) and thyrotropin (TSH) circulating levels were assessed in 7 normal subjects and in 17 patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e006d41634e91e72b3f6f0e6f66488
https://pubmed.ncbi.nlm.nih.gov/7851873