Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wilhelm Salmen"'
Autor:
Wilhelm Salmen, Liya Hu, Marina Bok, Natthawan Chaimongkol, Khalil Ettayebi, Stanislav V. Sosnovtsev, Kaundal Soni, B. Vijayalakshmi Ayyar, Sreejesh Shanker, Frederick H. Neill, Banumathi Sankaran, Robert L. Atmar, Mary K. Estes, Kim Y. Green, Viviana Parreño, B. V. Venkataram Prasad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral drugs. The GII.4 HuNoV causes most epidemics worldwide. This virus undergoes epochal
Externí odkaz:
https://doaj.org/article/486d0a138c0d4e78a9136004a332e7a2
Autor:
B. Vijayalakshmi Ayyar, Khalil Ettayebi, Wilhelm Salmen, Umesh C. Karandikar, Frederick H. Neill, Victoria R. Tenge, Sue E. Crawford, Erhard Bieberich, B. V. Venkataram Prasad, Robert L. Atmar, Mary K. Estes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Culture methods for studying human norovirus infection have been recently established. Here, Ayyar and colleagues use human intestinal enteroids to dissect viral entry mechanisms and show that CLIC-mediated endocytosis and wound repair pathways are e
Externí odkaz:
https://doaj.org/article/030cb570a98e4a098d6918d65d76b4f4
Autor:
Liya Hu, Wilhelm Salmen, Banumathi Sankaran, Yi Lasanajak, David F. Smith, Sue E. Crawford, Mary K. Estes, B. V. Venkataram Prasad
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
Group B rotaviruses have a unique fold in the glycan-binding domain specific for N- acetyllactosamine that potentially diverged from folds conserved in group A and C rotaviruses.
Externí odkaz:
https://doaj.org/article/ef78f4b9ef334254aa32a56da24343b0
Autor:
Liya Hu, Wilhelm Salmen, Rong Chen, Yi Zhou, Frederick Neill, James E. Crowe, Robert L. Atmar, Mary K. Estes, B. V. Venkataram Prasad
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
GII.4 variants of human noroviruses cause pandemic viral gastroenteritis. The atomic structure of GII.4 virus-like particles reveal novel insights into capsid stability, dynamics and antigenic presentation potentially useful for ongoing vaccine devel
Externí odkaz:
https://doaj.org/article/7c91c7eecd954bb198f4edea648f725b
Autor:
Gabriela Alvarado, Wilhelm Salmen, Khalil Ettayebi, Liya Hu, Banumathi Sankaran, Mary K. Estes, B. V. Venkataram Prasad, James E. Crowe
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Noroviruses can cause gastroenteritis and there is currently no licensed vaccine or specific treatment available. Here, the authors isolate human monoclonal antibodies and characterize one antibody (NORO-320) with broad reactivity to genogroup I and
Externí odkaz:
https://doaj.org/article/33925668740440828a0fc9a2f93f6e1b
Autor:
Khalil Ettayebi, Wilhelm Salmen, Kaoru Imai, Akifumi Hagi, Frederick H. Neill, Robert L. Atmar, B. V. Venkataram Prasad, Mary K. Estes
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Human norovirus (HuNoV) is the leading cause of epidemic and sporadic acute gastroenteritis worldwide. HuNoV transmission occurs predominantly by direct person-to-person contact, and its health burden is associated with poor hand hygiene and
Externí odkaz:
https://doaj.org/article/5a7b95a093b246958ba68ecfc5dd2196
Autor:
Liya Hu, Banumathi Sankaran, Daniel R. Laucirica, Ketki Patil, Wilhelm Salmen, Allan Chris M Ferreon, Phoebe S. Tsoi, Yi Lasanajak, David F. Smith, Sasirekha Ramani, Robert L. Atmar, Mary K. Estes, Josephine C. Ferreon, B. V. Venkataram Prasad
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Human rotaviruses (RV) bind to histo-blood group antigens (HBGA) for attachment, but how different viral genotypes interact with HBGA isn’t known. Here, Hu et al. report crystal structures of a prevalent and a neonate-specific RV in complex with HB
Externí odkaz:
https://doaj.org/article/226e37b8d4144a7d953870719068de7d
Autor:
Gabriela Alvarado, Wilhelm Salmen, Khalil Ettayebi, Liya Hu, Banumathi Sankaran, Mary K. Estes, B. V. Venkataram Prasad, James E. Crowe
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/74a2da5edb124e3abcc88612b0e1e394
Autor:
Victoria R. Tenge, Kosuke Murakami, Wilhelm Salmen, Shih-Ching Lin, Sue E. Crawford, Frederick H. Neill, B. V. Venkataram Prasad, Robert L. Atmar, Mary K. Estes
Publikováno v:
Viruses, Vol 13, Iss 6, p 998 (2021)
Laboratory cultivation of viruses is critical for determining requirements for viral replication, developing detection methods, identifying drug targets, and developing antivirals. Several viruses have a history of recalcitrance towards robust replic
Externí odkaz:
https://doaj.org/article/5309d0eb5c394148b88e0254ebe4eb92
Autor:
Banumathi Sankaran, Wilhelm Salmen, Liya Hu, Khalil Ettayebi, B. V. Venkataram Prasad, James E. Crowe, Gabriela Alvarado, Mary K. Estes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
The rational development of norovirus vaccine candidates requires a deep understanding of the antigenic diversity and mechanisms of neutralization of the virus. Here, we isolate and characterize a panel of broadly cross-reactive naturally occurring h