Acute resistance exercise and training reduce desmin phosphorylation at serine 31 in human skeletal muscle, making the protein less prone to cleavage

Autor: Daniel Jacko, Kirill Schaaf, Thorben Aussieker, Lukas Masur, Jonas Zacher, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Desmin intermediate filaments play a crucial role in stress transmission and mechano-protection. The loss of its integrity triggers myofibril breakdown and muscle atrophy for which desmin phosphorylation (pDes) is a priming factor. We invest

Externí odkaz: https://doaj.org/article/a0f26e8a77b749ea947bbed1382c151c

Whole‐body‐electro‐myostimulation for the care of inclusion body myositis—A case report

Autor: Nils Freitag, Boris Dragutinovic, Hannah L. Notbohm, Andre Filipovic, Thorsten Schiffer, Wilhelm Bloch, Moritz Schumann

Publikováno v: Clinical Case Reports, Vol 12, Iss 11, Pp n/a-n/a (2024)

Key Clinical Message External muscle stimulation, possibly combined with active muscle contraction, could improve physical functioning and performance in inclusion body myositis. Abstract Inclusion body myositis (IBM) is a chronic, progressive inflam

Externí odkaz: https://doaj.org/article/428242f269754dacbf9857e19936cb1c

Red Blood Cell Morphology Is Associated with Altered Hemorheological Properties and Fatigue in Patients with Long COVID

Autor: Marijke Grau, Alena Presche, Anna-Lena Krüger, Wilhelm Bloch, Björn Haiduk

Publikováno v: Biology, Vol 13, Iss 11, p 948 (2024)

Background: SARS-CoV-2 infection adversely affects rheological parameters, particularly red blood cell (RBC) aggregation and deformability, but whether these changes persist in patients suffering from Long-COVID (LC) and whether these changes are rel

Externí odkaz: https://doaj.org/article/c1880ab19b0047f3b656f734b942d7dd

Resistance training does not increase myocellular garbage dumps: A pilot study on lipofuscin in skeletal muscle fibers of resistance trained young men

Autor: Daniel Jacko, Lukas Masur, Kirill Schaaf, Jonas Zacher, Käthe Bersiner, Markus deMarées, Wilhelm Bloch, Sebastian Gehlert

Publikováno v: Physiological Reports, Vol 12, Iss 3, Pp n/a-n/a (2024)

Abstract Lipofuscin (LF) is an intracellular aggregate associated with proteostatic impairments, especially prevalent in nondividing skeletal muscle fibers. Reactive oxygen species (ROS) drive LF‐formation. Resistance training (RT) improves muscle

Externí odkaz: https://doaj.org/article/9de2453f360d4e1a83e0ee1c69311207

Global Alliance for the Promotion of Physical Activity: the Hamburg Declaration

Autor: Christian Gerloff, Sebastien Racinais, Mats Borjesson, Erich Müller, Hashel Al Tunaiji, Andrea Ermolao, Lars Engebretsen, Wilhelm Bloch, Richard Budgett, David Hughes, Dina Christina Janse van Rensburg, Hans Hauner, Susi Kriemler, Boris Gojanovic, Martin Scherer, Martine Duclos, Claus Reinsberger, Uğur Erdener, Mark Fulcher, Willem van Mechelen, Benedict Tan, Romain Seil, Luigi Di Luigi, Bernd Wolfarth, Jeroen Swart, Victoriya Badtieva, Theodora Papadopoulou, Maurizio Casasco, Norbert Bachl, Fabio Pigozzi, Jürgen M Steinacker, Anca Ionescu, Mike Miller, Yannis P Pitsiladis, Martin Halle, Robert Sallis, Natasha Jones, Luis B Sardinha, Matthew Payton Herring, Arno Schmidt-Trucksäss, Svitlana Drozdovska, Demitri Constantinou, Sandra Rozenštoka, Bülent Ülkar, Naama Constantini, Yiannis Koutedakis, Cheri A Blauwet, Daniel Neunhäuserer, Jasper Schipperijn, German Clénin, Janine Wendt, Anna Jegier, Sheng Zeng, Chiara Fossati, Roberto Vettor, Jane Thornton, Elin Kolle, Hans-Georg Predel, Winfried März, Dietrich Andresen, Pedro Manonelles Marqueta, Christian Kuhn, Eleanor Tillet, Melita Moore, Carolin Knoke, Olena Andrieieva, Friedhelm J Beucher, Jose-Antonio Casajus Mallen, Ju-Ho Chang, Lukas Declercq, Stephane Doutreleau, Thomas Fischbach, Anastasia N Fischer, Jeorge Franchella, Jan C Galle, Evelina Georgiades, Marcela González Gross, Andy Grote, Mikio Hiura, Kerstin Holze, Gerhard Huber, Mark R. Hutchinson, Kirsten Kappert-Gonther, Monika Kellerer, Yutaka Kimura, Agrita Kiopa, Bernd Kladny, Gerhard Koch, Greg Kolt, Stephan Kress, Jens Kröger, Roman Laszlo, Ralph Lehnert, François J Lhuissier, Kerstin Lüdtke, Shigeru Makita, Kirill Micallef-Stafrace, I. Renay Onur, Vahur Ööpik, Malgorzata Perl, Anastassios Philippou, Algirdas Raslanas, Ruediger Reer, Klaus Reinhardt, Nils Schumacher, Bernhard Schwaab, Ansgar Schwirtz, Masato Suzuki, Ralph Tiesler, Ulf Tippelt, Eve Unt, Thomas Weikert

Publikováno v: BMJ Open Sport & Exercise Medicine, Vol 9, Iss 3 (2023)

Non-communicable diseases (NCDs), including coronary heart disease, stroke, hypertension, type 2 diabetes, dementia, depression and cancers, are on the rise worldwide and are often associated with a lack of physical activity (PA). Globally, the level

Externí odkaz: https://doaj.org/article/dde24881880247e9948e2a63ef6703e6